5. One of the features of BIGSdb is that the stored datasets have
been manually curated to provide researchers with more accurate results.
6. A BIGSdb manual for a detailed description of BIGSdb function is available (https://bigsdb.readthedocs.io/en/latest/).
Acknowledgments
This work was supported by a PTR grant (PTR30-17) from the
Institut Pasteur. We would like to thank to Julien Guglielmini
(Bioinformatics and Biostatistics Hub, Institut Pasteur, Paris,
France) for incorporation of the BIGSdb plug-ins.
References
1. Herrmann JL, Bellenger E, Perolat P,
Baranton G, Saint Girons I (1992) Pulsedfield gel electrophoresis of NotI digests of leptospiral DNA: a new rapid method of serovar
identification.
J
Clin
Microbiol
30
(7):1696–1702
2. Majed Z, Bellenger E, Postic D, Pourcel C,
Baranton G, Picardeau M (2005) Identification
Fig. 3 Identification of potential infection sources. A minimum spanning tree was created using GrapeTree for
visualization of core genomic relationships of all available L. interrogans strains (n ¼ 299) isolated from
different hosts around the globe. The numbers inside the tree nodes indicate the cgCGs, and colors signify the
origins of the samples
20
Linda Grillova ´ and Mathieu Picardeau
been manually curated to provide researchers with more accurate results.
6. A BIGSdb manual for a detailed description of BIGSdb function is available (https://bigsdb.readthedocs.io/en/latest/).
Acknowledgments
This work was supported by a PTR grant (PTR30-17) from the
Institut Pasteur. We would like to thank to Julien Guglielmini
(Bioinformatics and Biostatistics Hub, Institut Pasteur, Paris,
France) for incorporation of the BIGSdb plug-ins.
References
1. Herrmann JL, Bellenger E, Perolat P,
Baranton G, Saint Girons I (1992) Pulsedfield gel electrophoresis of NotI digests of leptospiral DNA: a new rapid method of serovar
identification.
J
Clin
Microbiol
30
(7):1696–1702
2. Majed Z, Bellenger E, Postic D, Pourcel C,
Baranton G, Picardeau M (2005) Identification
Fig. 3 Identification of potential infection sources. A minimum spanning tree was created using GrapeTree for
visualization of core genomic relationships of all available L. interrogans strains (n ¼ 299) isolated from
different hosts around the globe. The numbers inside the tree nodes indicate the cgCGs, and colors signify the
origins of the samples
20
Linda Grillova ´ and Mathieu Picardeau