3 Label-Free, Ultrahigh-Speed, Direct Imaging and Tracking …
83
18. H. Isojima et al., Direct observation of intermediate states during the stepping motion of
kinesin-1. Nat. Chem. Biol. 12, 290–297 (2016)
19. H. Ueno et al., Simple dark-field microscopy with nanometer spatial precision and microsecond
temporal resolution. Biophys. J. 98(9), 2014–2023 (2010)
20. J.L. Martin et al., Anatomy of F 1 -ATPase powered rotation. Proc. Natl. Acad. Sci. 111(10),
3715–3720 (2014)
21. S. Faez et al., Fast, label-free tracking of single viruses and weakly scattering nanoparticles in
a nanofluidic optical fiber. ACS Nano 9(12), 12349–12357 (2015)
22. S. Enoki et al., Label-free single-particle imaging of the influenza virus by objective-type total
internal reflection dark-field microscopy. PLoS ONE 7(11), e49208 (2012)
23. B. Agnarsson et al., Evanescent light-scattering microscopy for label-free interfacial imaging:
from single sub-100 nm vesicles to live cells. ACS Nano 9(12), 11849–11862 (2015)
24. E. McLeod et al., High-throughput and label-free single nanoparticle sizing based on timeresolved on-chip microscopy. ACS Nano 9(3), 3265–3273 (2015)
25. P. Kukura et al., High-speed nanoscopic tracking of the position and orientation of a single
virus. Nat. Methods 6, 923–927 (2009)
26. S.M. Scherr et al., Real-time capture and visualization of individual viruses in complex media.
ACS Nano 10(2), 2827–2833 (2016)
27. G.G. Daaboul et al., Digital detection of exosomes by interferometric imaging. Sci. Rep. 6,
37246 (2016)
28. H.-M. Wu et al., Nanoscopic substructures of raft-mimetic liquid-ordered membrane domains
revealed by high-speed single-particle tracking. Sci. Rep. 6, 20542 (2016)
29. Y.-H. Lin, W.-L. Chang, C.-L. Hsieh, Shot-noise limited localization of single 20 nm gold
particles with nanometer spatial precision within microseconds. Opt. Express 22(8), 9159–9170
(2014)
30. Y. Yang et al., Label-free tracking of single organelle transportation in cells with nanometer
precision using a plasmonic imaging technique. Small 11(24), 2878–2884 (2015)
31. Y.-F. Huang et al., Coherent brightfield microscopy provides the spatiotemporal resolution to
study early stage viral infection in live cells. ACS Nano 11(3), 2575–2585 (2017)
32. Y.-F. Huang et al., Label-free, ultrahigh-speed, 3D observation of bidirectional and correlated intracellular cargo transport by coherent brightfield microscopy. Nanoscale 9, 6567–6574
(2017)
33. C. Kural et al., Tracking melanosomes inside a cell to study molecular motors and their interaction. Proc. Natl. Acad. Sci. 104(13), 5378–5382 (2007)
34. J.-S. Park et al., Label-free and live cell imaging by interferometric scattering microscopy.
Chem. Sci. 9(10), 2690–2697 (2018)
35. C.-Y. Cheng, Y.-H. Liao, C.-L. Hsieh, High-speed imaging and tracking of very small single
nanoparticles by contrast enhanced microscopy. Nanoscale. 11, 568–577 (2019)
36. C.-L. Hsieh, Label-free, ultrasensitive, ultrahigh-speed scattering-based interferometric imaging. Opt. Commun. 422, 69–74 (2018)
37. J. Hwang, W.E. Moerner, Interferometry of a single nanoparticle using the Gouy phase of a
focused laser beam. Opt. Commun. 280(2), 487–491 (2007)
38. C.F. Bohren, D.R. Huffman, Absorption and Scattering of Light by Small Particles (WileyVCH, 2004)
39. M.K. Kim, Digital holographic microscopy, in Digital Holographic Microscopy: Principles,
Techniques, and Applications (Springer, New York, 2011), pp. 149–190
40. V. Mico, Z. Zalevsky, J. García, Common-path phase-shifting digital holographic microscopy:
a way to quantitative phase imaging and superresolution. Opt. Commun. 281(17), 4273–4281
(2008)
41. J. Garcia-Sucerquia et al., Digital in-line holographic microscopy. Appl. Opt. 45(5), 836–850
(2006)
42. J. Ortega-Arroyo, P. Kukura, Interferometric scattering microscopy (iSCAT): new frontiers in
ultrafast and ultrasensitive optical microscopy. Phys. Chem. Chem. Phys. 14(45), 15625–15636
(2012)
83
18. H. Isojima et al., Direct observation of intermediate states during the stepping motion of
kinesin-1. Nat. Chem. Biol. 12, 290–297 (2016)
19. H. Ueno et al., Simple dark-field microscopy with nanometer spatial precision and microsecond
temporal resolution. Biophys. J. 98(9), 2014–2023 (2010)
20. J.L. Martin et al., Anatomy of F 1 -ATPase powered rotation. Proc. Natl. Acad. Sci. 111(10),
3715–3720 (2014)
21. S. Faez et al., Fast, label-free tracking of single viruses and weakly scattering nanoparticles in
a nanofluidic optical fiber. ACS Nano 9(12), 12349–12357 (2015)
22. S. Enoki et al., Label-free single-particle imaging of the influenza virus by objective-type total
internal reflection dark-field microscopy. PLoS ONE 7(11), e49208 (2012)
23. B. Agnarsson et al., Evanescent light-scattering microscopy for label-free interfacial imaging:
from single sub-100 nm vesicles to live cells. ACS Nano 9(12), 11849–11862 (2015)
24. E. McLeod et al., High-throughput and label-free single nanoparticle sizing based on timeresolved on-chip microscopy. ACS Nano 9(3), 3265–3273 (2015)
25. P. Kukura et al., High-speed nanoscopic tracking of the position and orientation of a single
virus. Nat. Methods 6, 923–927 (2009)
26. S.M. Scherr et al., Real-time capture and visualization of individual viruses in complex media.
ACS Nano 10(2), 2827–2833 (2016)
27. G.G. Daaboul et al., Digital detection of exosomes by interferometric imaging. Sci. Rep. 6,
37246 (2016)
28. H.-M. Wu et al., Nanoscopic substructures of raft-mimetic liquid-ordered membrane domains
revealed by high-speed single-particle tracking. Sci. Rep. 6, 20542 (2016)
29. Y.-H. Lin, W.-L. Chang, C.-L. Hsieh, Shot-noise limited localization of single 20 nm gold
particles with nanometer spatial precision within microseconds. Opt. Express 22(8), 9159–9170
(2014)
30. Y. Yang et al., Label-free tracking of single organelle transportation in cells with nanometer
precision using a plasmonic imaging technique. Small 11(24), 2878–2884 (2015)
31. Y.-F. Huang et al., Coherent brightfield microscopy provides the spatiotemporal resolution to
study early stage viral infection in live cells. ACS Nano 11(3), 2575–2585 (2017)
32. Y.-F. Huang et al., Label-free, ultrahigh-speed, 3D observation of bidirectional and correlated intracellular cargo transport by coherent brightfield microscopy. Nanoscale 9, 6567–6574
(2017)
33. C. Kural et al., Tracking melanosomes inside a cell to study molecular motors and their interaction. Proc. Natl. Acad. Sci. 104(13), 5378–5382 (2007)
34. J.-S. Park et al., Label-free and live cell imaging by interferometric scattering microscopy.
Chem. Sci. 9(10), 2690–2697 (2018)
35. C.-Y. Cheng, Y.-H. Liao, C.-L. Hsieh, High-speed imaging and tracking of very small single
nanoparticles by contrast enhanced microscopy. Nanoscale. 11, 568–577 (2019)
36. C.-L. Hsieh, Label-free, ultrasensitive, ultrahigh-speed scattering-based interferometric imaging. Opt. Commun. 422, 69–74 (2018)
37. J. Hwang, W.E. Moerner, Interferometry of a single nanoparticle using the Gouy phase of a
focused laser beam. Opt. Commun. 280(2), 487–491 (2007)
38. C.F. Bohren, D.R. Huffman, Absorption and Scattering of Light by Small Particles (WileyVCH, 2004)
39. M.K. Kim, Digital holographic microscopy, in Digital Holographic Microscopy: Principles,
Techniques, and Applications (Springer, New York, 2011), pp. 149–190
40. V. Mico, Z. Zalevsky, J. García, Common-path phase-shifting digital holographic microscopy:
a way to quantitative phase imaging and superresolution. Opt. Commun. 281(17), 4273–4281
(2008)
41. J. Garcia-Sucerquia et al., Digital in-line holographic microscopy. Appl. Opt. 45(5), 836–850
(2006)
42. J. Ortega-Arroyo, P. Kukura, Interferometric scattering microscopy (iSCAT): new frontiers in
ultrafast and ultrasensitive optical microscopy. Phys. Chem. Chem. Phys. 14(45), 15625–15636
(2012)