Chapter 13
Computational Biomechanics of the
Brain in the Operating Theatre
Hadrien Courtecuisse, Fanny Morin, Ingerid Reinertsen, Yohan Payan,
and Matthieu Chabanas
13.1 Introduction
Surgical resection of a brain tumour is a precise and delicate procedure. It requires
to remove the entire tumour, in order to prevent recurrence, while preserving
as much as possible of surrounding healthy or eloquent tissues, to reduce the
probability of functional disorders. However, tumour borders, especially when
located deep into the parenchyma, are usually not clearly visible among healthy
tissues. In addition, important displacements and deformations may occur between
pre-operative images used for diagnosis and intra-operative configurations, which
raise significant difficulties for the treatment.
The brain-shift corresponds to an intra-operative deformation of soft tissues,
affecting the localisation of internal structures of the brain. Multiple factors can
impact the amplitude and direction of this nonlinear deformation: the loss of
cerebrospinal fluid (CSF), the positioning of the patient during surgery, the size
H. Courtecuisse
ICube, Strasbourg University, CNRS, Strasbourg, France
e-mail: hcourtecuisse@unistra.fr
F. Morin
ICube, Strasbourg University, CNRS, Strasbourg, France
University of Grenoble Alpes, CNRS, Grenoble, France
e-mail: Fanny.Morin@univ-grenoble-alpes.fr
I. Reinertsen
Department of Medical Technology, SINTEF, Trondheim, Norway
e-mail: Ingerid.Reinertsen@sintef.no
Y. Payan · M. Chabanas ()
University of Grenoble Alpes, CNRS, Grenoble, France
e-mail: Yohan.Payan@univ-grenoble-alpes.fr; Matthieu.Chabanas@univ-grenoble-alpes.fr
© Springer Nature Switzerland AG 2019
K. Miller (ed.), Biomechanics of the Brain, Biological and Medical Physics,
Biomedical Engineering, https://doi.org/10.1007/978-3-030-04996-6_13
321
Computational Biomechanics of the
Brain in the Operating Theatre
Hadrien Courtecuisse, Fanny Morin, Ingerid Reinertsen, Yohan Payan,
and Matthieu Chabanas
13.1 Introduction
Surgical resection of a brain tumour is a precise and delicate procedure. It requires
to remove the entire tumour, in order to prevent recurrence, while preserving
as much as possible of surrounding healthy or eloquent tissues, to reduce the
probability of functional disorders. However, tumour borders, especially when
located deep into the parenchyma, are usually not clearly visible among healthy
tissues. In addition, important displacements and deformations may occur between
pre-operative images used for diagnosis and intra-operative configurations, which
raise significant difficulties for the treatment.
The brain-shift corresponds to an intra-operative deformation of soft tissues,
affecting the localisation of internal structures of the brain. Multiple factors can
impact the amplitude and direction of this nonlinear deformation: the loss of
cerebrospinal fluid (CSF), the positioning of the patient during surgery, the size
H. Courtecuisse
ICube, Strasbourg University, CNRS, Strasbourg, France
e-mail: hcourtecuisse@unistra.fr
F. Morin
ICube, Strasbourg University, CNRS, Strasbourg, France
University of Grenoble Alpes, CNRS, Grenoble, France
e-mail: Fanny.Morin@univ-grenoble-alpes.fr
I. Reinertsen
Department of Medical Technology, SINTEF, Trondheim, Norway
e-mail: Ingerid.Reinertsen@sintef.no
Y. Payan · M. Chabanas ()
University of Grenoble Alpes, CNRS, Grenoble, France
e-mail: Yohan.Payan@univ-grenoble-alpes.fr; Matthieu.Chabanas@univ-grenoble-alpes.fr
© Springer Nature Switzerland AG 2019
K. Miller (ed.), Biomechanics of the Brain, Biological and Medical Physics,
Biomedical Engineering, https://doi.org/10.1007/978-3-030-04996-6_13
321