Chapter 8
Dynamics of Cerebrospinal Fluid: From
Theoretical Models to Clinical
Applications
Laurent Geregele, Olivier Baledent, Romain Manet, Afroditi Lalou,
Slawomir Barszcz, Magdalena Kasprowicz, Piotr Smielewski,
John D. Pickard, Marek Czosnyka, and Zofia Czosnyka
8.1 Introduction
Modelling of cerebrospinal fluid (CSF) circulation usually differs from models of
brain tissue deformation. Hydrodynamics of CSF and its links with cerebral blood
flow (CBF) are here of interest, as opposed to displacement of anatomical structures
L. Geregele
Neurosurgical Unit, University of Cambridge, Department of Clinical Neurosciences, Cambridge,
UK
Department of Intensive Care, Ramsay Générale de Santé, Hôpital privé de la Loire,
Saint Etienne, France
O. Baledent
Department of Imaging and Biophysics, Jules Verne University hospital, Amiens, France
R. Manet
Department of Neurosurgery B, Neurological Hospital Wertheimer, University of Lyon, Lyon,
France
A. Lalou · P. Smielewski · J. D. Pickard · Z. Czosnyka
Neurosurgical Unit, University of Cambridge, Department of Clinical Neurosciences, Cambridge,
UK
S. Barszcz
Department of Neurosurgery and Traumatology, Public Pediatric Teaching Clinical Hospital,
Medical University of Warsaw, Warsaw, Poland
M. Kasprowicz
Institute of Biomedical Engineering and Instrumentation, Wroclaw University of Technology,
Wrocław, Poland
M. Czosnyka ()
Neurosurgical Unit, University of Cambridge, Department of Clinical Neurosciences, Cambridge,
UK
Institute of Electronic Systems, Warsaw Univeristy of Technology, Warsaw, Poland
e-mail: mc141@medschl.cam.ac.uk
© Springer Nature Switzerland AG 2019
K. Miller (ed.), Biomechanics of the Brain, Biological and Medical Physics,
Biomedical Engineering, https://doi.org/10.1007/978-3-030-04996-6_8
181
Dynamics of Cerebrospinal Fluid: From
Theoretical Models to Clinical
Applications
Laurent Geregele, Olivier Baledent, Romain Manet, Afroditi Lalou,
Slawomir Barszcz, Magdalena Kasprowicz, Piotr Smielewski,
John D. Pickard, Marek Czosnyka, and Zofia Czosnyka
8.1 Introduction
Modelling of cerebrospinal fluid (CSF) circulation usually differs from models of
brain tissue deformation. Hydrodynamics of CSF and its links with cerebral blood
flow (CBF) are here of interest, as opposed to displacement of anatomical structures
L. Geregele
Neurosurgical Unit, University of Cambridge, Department of Clinical Neurosciences, Cambridge,
UK
Department of Intensive Care, Ramsay Générale de Santé, Hôpital privé de la Loire,
Saint Etienne, France
O. Baledent
Department of Imaging and Biophysics, Jules Verne University hospital, Amiens, France
R. Manet
Department of Neurosurgery B, Neurological Hospital Wertheimer, University of Lyon, Lyon,
France
A. Lalou · P. Smielewski · J. D. Pickard · Z. Czosnyka
Neurosurgical Unit, University of Cambridge, Department of Clinical Neurosciences, Cambridge,
UK
S. Barszcz
Department of Neurosurgery and Traumatology, Public Pediatric Teaching Clinical Hospital,
Medical University of Warsaw, Warsaw, Poland
M. Kasprowicz
Institute of Biomedical Engineering and Instrumentation, Wroclaw University of Technology,
Wrocław, Poland
M. Czosnyka ()
Neurosurgical Unit, University of Cambridge, Department of Clinical Neurosciences, Cambridge,
UK
Institute of Electronic Systems, Warsaw Univeristy of Technology, Warsaw, Poland
e-mail: mc141@medschl.cam.ac.uk
© Springer Nature Switzerland AG 2019
K. Miller (ed.), Biomechanics of the Brain, Biological and Medical Physics,
Biomedical Engineering, https://doi.org/10.1007/978-3-030-04996-6_8
181