12.3 General Structure Models Interaction of Laser Radiation with a Biotissue
183
Experimental measurement:
I = I (n j , χ j , d j , σ, D, q) is reflected signal on simulated
biological structures.
Calculate:
I = I (n j , χ j , d j , σ, D, q)−the dependences of the laser radiation intensity
on the refractive index and absorption coefficient
for a system of blood vessels in
the outer layer of the dermis for various absorption
coefficients of the epidermis and dermis.
Light Scattering by Dielectric Bodies of Irregular Shape in a Layered Medium
for Case In vivo
Input parameters:
n j (λ) + iχ j (λ)is refractive index of the jth layer,
d j is thickness of the jth layer,
λ is the wavelength,
r
i
1 is the radius of the cell nucleus of the ith particle,
r
i
2 is the radius of the plasma membrane of the ith particle,
m
i
1 (λ) is refractive index of the cell nucleus of the ith particle,
m
i
2 (λ) is refractive index of the plasma membrane
of the ith particle,
H is the hematocrit in the capillary,
f is the volume concentration of hemoglobin in erythrocytes,
S is the degree of oxygenation of blood.
Output parameters:
I = I (n j , χ j , m
i
1 , m
i
2 , r
i
1 , r
i
2 , S, H, f, d j ) is the dependence of the laser radiation
intensity on the refractive index
epidermis, derma, blood corpuscles,
theoretical determination the function of size distribution for blood cells.
Experimental measurement:
I = I (n j , χ j , m
i
1 , m
i
2 , r
i
1 , r
i
2 , S, H, f, d j ) is reflected signal on simulated biological
structure
Calculate:
1. I = I (n j , χ j , m
i
1 , m
i
2 , r
i
1 , r
i
2 , S, H, f, d j ),
2. K HbO 2 is the normalized spectra of action of laser radiation on oxyhemoglobin,
3. K Hb is the normalized spectra of action of laser radiation on deoxyhemoglobin,
4. the function of size distribution for blood cells.