R
Radiochemical yield. See (RCY)
Radiofluorination with no-carrier-added, 267
Radiolabeled exosomes, 167
Radiolabeled graphene. See (Radio-Graphene)
Radiolabeled liposomes, 110
Radiolabeling, 144, 210, 241, 340
Radionanomedicine, 4
Radionanomedicine platform, 232, 245
Radionuclide imaging of EVs, 143
99 mTc Radiolabeled EVs, 145
Raman spectroscopy, 417
Reduced Graphene Oxides. See (ROGs)
Renal excretion, 348
RGD peptide, 235
Rhenium-186, 69
Rhenium-188, 69, 244
S
Secreted Protein, Acidic and Rich in Cysteine.
See (SPARC)
Selective cargo release, 188
Silica, 189
Silica nanoparticles, 27, 192, 315
Simplified Reference Tissue Model. See
(SRTM)
Single-Walled Carbon Nanotubes. See
(SWNTs)
Small molecules, 214
Specific trapping, 220
SPECT. See (Single-Photon Emission
Computed Tomography)
SPECT/CT, 282
SPECT/MR, 282
Spleen, 398
Stealth effect, 336
Streptavidin, 144
Superparamagnetic Iron Oxide Nanoparticles.
See (SPIONs)
Surface charge, 322
Surface modification, 186
Surface-Enhanced Raman Scattering. See
(SERS)
T
Targeted delivery, 2
Targeted drug delivery, 175
Target-mediated drug disposition. See (TMDD)
T-cell independent Mechanism. See (TI
Mechanism)
Technetium-99m, 61, 72
Technetium-99m-HMPAO, 145
Technetium-99m-HMPAO Labeled EVs, 147
Technetium-99m-HSA, 113
Technetium-99 m-labeled PEGylated
Liposomes, 380
Technetium-99m-tricarbonyl, 146
Tetrazine. See (Tz)
Th2 Activation, 397
Theranostic, 3, 56, 97, 167, 212, 284, 432
Theranostic dendrimer platform, 116
Theranostic use, 9
Therapeutic radionuclides, 212, 435
Therapeutic target, 169
Time–activity curves, 295
Tissue macrophages, 394, 396
Toll-like receptors. See (TLRs)
Toxicity, 2
Trace amount, 3
Tracer capability, 3
Tracer kinetic, 4, 294
Tracer principle, 7
Trans-cyclooctene. See (TCO)
Transitional metal dichalcogenides. See
(TMDCs)
Tropism of EVs, 158
Tumor clearance, 305
Tumor-specific binding, 305
Tunable degradability, 188
U
Ultrasmall fluorescent dye-encapsulated silica
PET-optical hybrid nanoparticles. See
(Cornell dots)
Upconversion nanoparticles. See (UCNPs)
V
Van der Vaals force, 186
X
XTEN, 383
Z
Zirconium-89, 243
ZnO nanoparticles, 33
Zwitterion, 383
Zwitterion coating, 336, 337
Zwitterionic modification, 8
446
Index
Radiochemical yield. See (RCY)
Radiofluorination with no-carrier-added, 267
Radiolabeled exosomes, 167
Radiolabeled graphene. See (Radio-Graphene)
Radiolabeled liposomes, 110
Radiolabeling, 144, 210, 241, 340
Radionanomedicine, 4
Radionanomedicine platform, 232, 245
Radionuclide imaging of EVs, 143
99 mTc Radiolabeled EVs, 145
Raman spectroscopy, 417
Reduced Graphene Oxides. See (ROGs)
Renal excretion, 348
RGD peptide, 235
Rhenium-186, 69
Rhenium-188, 69, 244
S
Secreted Protein, Acidic and Rich in Cysteine.
See (SPARC)
Selective cargo release, 188
Silica, 189
Silica nanoparticles, 27, 192, 315
Simplified Reference Tissue Model. See
(SRTM)
Single-Walled Carbon Nanotubes. See
(SWNTs)
Small molecules, 214
Specific trapping, 220
SPECT. See (Single-Photon Emission
Computed Tomography)
SPECT/CT, 282
SPECT/MR, 282
Spleen, 398
Stealth effect, 336
Streptavidin, 144
Superparamagnetic Iron Oxide Nanoparticles.
See (SPIONs)
Surface charge, 322
Surface modification, 186
Surface-Enhanced Raman Scattering. See
(SERS)
T
Targeted delivery, 2
Targeted drug delivery, 175
Target-mediated drug disposition. See (TMDD)
T-cell independent Mechanism. See (TI
Mechanism)
Technetium-99m, 61, 72
Technetium-99m-HMPAO, 145
Technetium-99m-HMPAO Labeled EVs, 147
Technetium-99m-HSA, 113
Technetium-99 m-labeled PEGylated
Liposomes, 380
Technetium-99m-tricarbonyl, 146
Tetrazine. See (Tz)
Th2 Activation, 397
Theranostic, 3, 56, 97, 167, 212, 284, 432
Theranostic dendrimer platform, 116
Theranostic use, 9
Therapeutic radionuclides, 212, 435
Therapeutic target, 169
Time–activity curves, 295
Tissue macrophages, 394, 396
Toll-like receptors. See (TLRs)
Toxicity, 2
Trace amount, 3
Tracer capability, 3
Tracer kinetic, 4, 294
Tracer principle, 7
Trans-cyclooctene. See (TCO)
Transitional metal dichalcogenides. See
(TMDCs)
Tropism of EVs, 158
Tumor clearance, 305
Tumor-specific binding, 305
Tunable degradability, 188
U
Ultrasmall fluorescent dye-encapsulated silica
PET-optical hybrid nanoparticles. See
(Cornell dots)
Upconversion nanoparticles. See (UCNPs)
V
Van der Vaals force, 186
X
XTEN, 383
Z
Zirconium-89, 243
ZnO nanoparticles, 33
Zwitterion, 383
Zwitterion coating, 336, 337
Zwitterionic modification, 8
446
Index
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