Chapter 1
Introduction
Dong Soo Lee
Abstract Radionanomedicine is a novel discipline of combined nuclear and
nanomedicine. Nuclear medicine has an almost one century of history since its birth
and has been successfully applied for clinical application. Clinical nuclear medicine
ranges from therapy with imaging theranostic to hybrid imaging such as positron
emission tomography/computed tomography (PET/CT), PET/magnetic resonance
imaging (PET/MRI), single photon emission computed tomography (SPECT)/CT
or gamma camera imaging. Theranostic application of nuclear medicine is recently
emphasized by the urgent needs raised by individualized or personalized medicine.
Radionanomedicine is a novel discipline of combined nuclear and nanomedicine.
Nuclear medicine has an almost one century of history since its birth and has been
successfully applied for clinical application. Clinical nuclear medicine ranges from
therapy with imaging theranostic to hybrid imaging such as positron emission
tomography/computed tomography (PET/CT), PET/magnetic resonance imaging
(PET/MRI), single photon emission computed tomography (SPECT)/CT or gamma
camera imaging. Theranostic application of nuclear medicine is recently emphasized by the urgent needs raised by individualized or personalized medicine.
Nuclear medicine is based on the tracer principle or tracer technology, which
enabled the birth of clinical nuclear medicine despite radiation hazard of radionuclides for therapy and especially imaging. Very small amount of radionuclides or
radioisotopes are used for clinical human use and this makes the use of trace
amount of pharmaceuticals which does not raise any concern of pharmacologic
effect. According to the regulations widely accepted by drug agencies, microdosing
D. S. Lee (&)
Department of Nuclear Medicine, Seoul National University College
of Medicine, Seoul 03080, Republic of Korea
e-mail: dsl@snu.ac.kr
D. S. Lee
Department of Molecular Medicine and Biopharmaceutical Sciences,
Graduate School of Convergence Science and Technology,
Seoul National University, Seoul 03080, Republic of Korea
© Springer International Publishing AG, part of Springer Nature 2018
D. S. Lee (ed.), Radionanomedicine, Biological and Medical Physics,
Biomedical Engineering, https://doi.org/10.1007/978-3-319-67720-0_1
1
Introduction
Dong Soo Lee
Abstract Radionanomedicine is a novel discipline of combined nuclear and
nanomedicine. Nuclear medicine has an almost one century of history since its birth
and has been successfully applied for clinical application. Clinical nuclear medicine
ranges from therapy with imaging theranostic to hybrid imaging such as positron
emission tomography/computed tomography (PET/CT), PET/magnetic resonance
imaging (PET/MRI), single photon emission computed tomography (SPECT)/CT
or gamma camera imaging. Theranostic application of nuclear medicine is recently
emphasized by the urgent needs raised by individualized or personalized medicine.
Radionanomedicine is a novel discipline of combined nuclear and nanomedicine.
Nuclear medicine has an almost one century of history since its birth and has been
successfully applied for clinical application. Clinical nuclear medicine ranges from
therapy with imaging theranostic to hybrid imaging such as positron emission
tomography/computed tomography (PET/CT), PET/magnetic resonance imaging
(PET/MRI), single photon emission computed tomography (SPECT)/CT or gamma
camera imaging. Theranostic application of nuclear medicine is recently emphasized by the urgent needs raised by individualized or personalized medicine.
Nuclear medicine is based on the tracer principle or tracer technology, which
enabled the birth of clinical nuclear medicine despite radiation hazard of radionuclides for therapy and especially imaging. Very small amount of radionuclides or
radioisotopes are used for clinical human use and this makes the use of trace
amount of pharmaceuticals which does not raise any concern of pharmacologic
effect. According to the regulations widely accepted by drug agencies, microdosing
D. S. Lee (&)
Department of Nuclear Medicine, Seoul National University College
of Medicine, Seoul 03080, Republic of Korea
e-mail: dsl@snu.ac.kr
D. S. Lee
Department of Molecular Medicine and Biopharmaceutical Sciences,
Graduate School of Convergence Science and Technology,
Seoul National University, Seoul 03080, Republic of Korea
© Springer International Publishing AG, part of Springer Nature 2018
D. S. Lee (ed.), Radionanomedicine, Biological and Medical Physics,
Biomedical Engineering, https://doi.org/10.1007/978-3-319-67720-0_1
1