potential of mesenchymal stem cell-derived EVs have been widely investigated in
the fields such as pulmonary hypertension [65], myocardial infarction injury [66],
and acute kidney injury [67].
6.5 Perspectives and Conclusion
Over the past decades, there have been extensive researches carried out on cargos,
biogenesis, pathophysiological function, and biomedical application of mammalian
extracellular vesicles (also known as exosomes and ectosomes). Although a
Fig. 6.5 Emergent property of EVs at a single vesicle level (a) or at a systems level as a whole
(b). A holistic systems biology approach based on the concept of emergent properties of EVs is
critical to elucidate the complex pathological functions of EVs, to decode the secrets of life as well
as to develop novel EV-based diagnostics and therapeutics against hard-to-cure diseases [1].
Reprinted with permission from [1]
6 Endogenous Radionanomedicine: Extracellular Vesicles
135
the fields such as pulmonary hypertension [65], myocardial infarction injury [66],
and acute kidney injury [67].
6.5 Perspectives and Conclusion
Over the past decades, there have been extensive researches carried out on cargos,
biogenesis, pathophysiological function, and biomedical application of mammalian
extracellular vesicles (also known as exosomes and ectosomes). Although a
Fig. 6.5 Emergent property of EVs at a single vesicle level (a) or at a systems level as a whole
(b). A holistic systems biology approach based on the concept of emergent properties of EVs is
critical to elucidate the complex pathological functions of EVs, to decode the secrets of life as well
as to develop novel EV-based diagnostics and therapeutics against hard-to-cure diseases [1].
Reprinted with permission from [1]
6 Endogenous Radionanomedicine: Extracellular Vesicles
135