Pieck M, Yuan Y, Godfrey J, Fisher C, Zolj S, Vaughan D, Thomas N, Wu C, Ramos J, Lee N,
Normanly J, Celenza JL (2015) Auxin and tryptophan homeostasis are facilitated by the ISS1/
VAS1 aromatic aminotransferase in Arabidopsis. Genetics 201:185–199
Pommerrenig B, Feussner K, Zierer W, Rabinovych V, Klebl F, Feussner I, Sauer N (2011)
Phloem-specific expression of Yang cycle genes and identification of novel Yang cycle enzymes
in Plantago and Arabidopsis. Plant Cell 23:1904–1919
Price MB, Jelesko J, Okumoto S (2012) Glutamate receptor homologs in plants: functions and
evolutionary origins. Front Plant Sci 3:235
Pruess DL, Scannell JP, Kellett M, Ax HA, Janecek J, Williams TH, Stempel A, Berger J (1974)
Antimetabolites produced by microorganisms. X. L-2-Amino4-(2-aminoe- thoxy)-trans-3butenoic acid. J Antibiot 27:229–233
Rando RR (1974a) Chemistry and enzymology of Kcat inhibitors. Science 185:320–324
Rando RR (1974b) Irreversible inhibition of aspartate aminotransferase by 2-amino-3-butenoic
acid. Biochemist 13(19):3859–3863
Ravanel S, Gakière B, Job D, Douce R (1998) The specific features of methionine biosynthesis and
metabolism in plants. Proc Natl Acad Sci U S A 95:7805–7812
Ravanel S, Cherest H, Jabrin S, Grunwald D, Surdin-Kerjan Y, Douce R, Rébeillé F (2001) Tetrahydrofolate biosynthesis in plants: molecular and functional characterization of dihydrofolate
synthetase and three isoforms of folylpolyglutamate synthetase in Arabidopsis thaliana.
Proc Natl Acad Sci U S A 98:15360–15365
Ravanel S, Block MA, Rippert P, Jabrin S, Curien G, Rébeillé F, Douce R (2004) Methionine
metabolism in plants: chloroplasts are autonomous for de novo methionine synthesis and can
import S-adenosylmethionine from the cytosol. J Biol Chem 279(21):22548–22557
Reyes-Hernández BJ, Srivastava AC, Ugartechea-Chirino Y, Shishkova S, Ramos-Parra PA, LiraRuan V, Díaz de la Garza RI, Dong G, Moon JC, Blancaflor EB, Dubrovsky JR (2014) The
root indeterminacy-to-determinacy developmental switch is operated through a folate-dependent
pathway in Arabidopsis thaliana. New Phytol 202:1223–1236
Riemenschneider A, Wegele R, Schmidt A, Papenbrock J (2005) Isolation and characterization of a
d-cysteine desulhydrase protein from Arabidopsis thaliana. FEBS J 272:1291–1304
Robert S, Raikhel NV, Hicks G (2009) Powerful partners: arabidopsis and chemical genomics.
Arabidopsis Book 7:e0109
Robinson D (2005) Integrated root responses to variations in nutrient supply. In: BassiriRad H
(ed) Nutrient acquisition by plants: an ecological perspective. Springer, Berlin, Heidelberg,
pp 43–61
Rodrigues-Pousada RA, De Rycke R, Dedonder A, Van Caeneghem W, Engler G, Van Montagu M,
Van Der Straeten D (1993) The Arabidopsis 1-aminocyclopropane-1-carboxylatesynthase gene
1 is expressed during early development. Plant Cell 5:897–911
Roje S, Chan SY, Kaplan F, Raymond RK, Horne DW, Appling DR et al (2002a) Metabolic engineering in yeast demonstrates that s-adenosylmethionine controls flux through the methylene
tetrahydrofolate reductase reaction in vivo. J Biol Chem 277:4056–4061
Roje S, Janave MT, Ziemak MJ, Hanson AD (2002b) Cloning and characterization of mitochondrial 5-formyltetrahydrofolate cycloligase from higher plants. J Biol Chem 277:42748–42754
Romero LC, Aroca MA, Laureano-Marin AM, Moreno I, Garcia I, Gotor C (2014) Cysteine and
cysteine-related signaling pathways in Arabidopsis thaliana. Mol Plant 7(2):264–272
Rubin G, Tohge T, Matsuda F, Saito K, Scheible WR (2009) Members of the LBD family of
transcription factors repress anthocyanin synthesis and affect additional nitrogen responses in
Arabidopsis. Plant Cell 21:3567–3584
Růžička K, Ljung K, Vanneste S, Podhorská R, Beeckman T, Friml J, Benková E (2007)
Ethylene regulates root growth through effects on auxin biosynthesis and transport-dependent
auxin distribution. Plant Cell 19:2197–2212
Rzewuski G, Cornell KA, Rooney L, Bürstenbinder K, Wirtz M, Hell R, Sauter M (2007) OsMTN
encodes a 5
0 -methylthioadenosine nucleosidase that is up-regulated during submergenceinduced ethylene synthesis in rice (Oryza sativa L.) J Exp Bot 58:1505–1514
Saftner R (1989) Effects of organic amines on α-aminoisobutyric acid uptake into the vacuole and
on ethylene production by tomato pericarp slices. Physiol Plant 75(4):485–491
From Aspartate to Ethylene: Central Role of N, C, and S Shuttles by. . .
289
Normanly J, Celenza JL (2015) Auxin and tryptophan homeostasis are facilitated by the ISS1/
VAS1 aromatic aminotransferase in Arabidopsis. Genetics 201:185–199
Pommerrenig B, Feussner K, Zierer W, Rabinovych V, Klebl F, Feussner I, Sauer N (2011)
Phloem-specific expression of Yang cycle genes and identification of novel Yang cycle enzymes
in Plantago and Arabidopsis. Plant Cell 23:1904–1919
Price MB, Jelesko J, Okumoto S (2012) Glutamate receptor homologs in plants: functions and
evolutionary origins. Front Plant Sci 3:235
Pruess DL, Scannell JP, Kellett M, Ax HA, Janecek J, Williams TH, Stempel A, Berger J (1974)
Antimetabolites produced by microorganisms. X. L-2-Amino4-(2-aminoe- thoxy)-trans-3butenoic acid. J Antibiot 27:229–233
Rando RR (1974a) Chemistry and enzymology of Kcat inhibitors. Science 185:320–324
Rando RR (1974b) Irreversible inhibition of aspartate aminotransferase by 2-amino-3-butenoic
acid. Biochemist 13(19):3859–3863
Ravanel S, Gakière B, Job D, Douce R (1998) The specific features of methionine biosynthesis and
metabolism in plants. Proc Natl Acad Sci U S A 95:7805–7812
Ravanel S, Cherest H, Jabrin S, Grunwald D, Surdin-Kerjan Y, Douce R, Rébeillé F (2001) Tetrahydrofolate biosynthesis in plants: molecular and functional characterization of dihydrofolate
synthetase and three isoforms of folylpolyglutamate synthetase in Arabidopsis thaliana.
Proc Natl Acad Sci U S A 98:15360–15365
Ravanel S, Block MA, Rippert P, Jabrin S, Curien G, Rébeillé F, Douce R (2004) Methionine
metabolism in plants: chloroplasts are autonomous for de novo methionine synthesis and can
import S-adenosylmethionine from the cytosol. J Biol Chem 279(21):22548–22557
Reyes-Hernández BJ, Srivastava AC, Ugartechea-Chirino Y, Shishkova S, Ramos-Parra PA, LiraRuan V, Díaz de la Garza RI, Dong G, Moon JC, Blancaflor EB, Dubrovsky JR (2014) The
root indeterminacy-to-determinacy developmental switch is operated through a folate-dependent
pathway in Arabidopsis thaliana. New Phytol 202:1223–1236
Riemenschneider A, Wegele R, Schmidt A, Papenbrock J (2005) Isolation and characterization of a
d-cysteine desulhydrase protein from Arabidopsis thaliana. FEBS J 272:1291–1304
Robert S, Raikhel NV, Hicks G (2009) Powerful partners: arabidopsis and chemical genomics.
Arabidopsis Book 7:e0109
Robinson D (2005) Integrated root responses to variations in nutrient supply. In: BassiriRad H
(ed) Nutrient acquisition by plants: an ecological perspective. Springer, Berlin, Heidelberg,
pp 43–61
Rodrigues-Pousada RA, De Rycke R, Dedonder A, Van Caeneghem W, Engler G, Van Montagu M,
Van Der Straeten D (1993) The Arabidopsis 1-aminocyclopropane-1-carboxylatesynthase gene
1 is expressed during early development. Plant Cell 5:897–911
Roje S, Chan SY, Kaplan F, Raymond RK, Horne DW, Appling DR et al (2002a) Metabolic engineering in yeast demonstrates that s-adenosylmethionine controls flux through the methylene
tetrahydrofolate reductase reaction in vivo. J Biol Chem 277:4056–4061
Roje S, Janave MT, Ziemak MJ, Hanson AD (2002b) Cloning and characterization of mitochondrial 5-formyltetrahydrofolate cycloligase from higher plants. J Biol Chem 277:42748–42754
Romero LC, Aroca MA, Laureano-Marin AM, Moreno I, Garcia I, Gotor C (2014) Cysteine and
cysteine-related signaling pathways in Arabidopsis thaliana. Mol Plant 7(2):264–272
Rubin G, Tohge T, Matsuda F, Saito K, Scheible WR (2009) Members of the LBD family of
transcription factors repress anthocyanin synthesis and affect additional nitrogen responses in
Arabidopsis. Plant Cell 21:3567–3584
Růžička K, Ljung K, Vanneste S, Podhorská R, Beeckman T, Friml J, Benková E (2007)
Ethylene regulates root growth through effects on auxin biosynthesis and transport-dependent
auxin distribution. Plant Cell 19:2197–2212
Rzewuski G, Cornell KA, Rooney L, Bürstenbinder K, Wirtz M, Hell R, Sauter M (2007) OsMTN
encodes a 5
0 -methylthioadenosine nucleosidase that is up-regulated during submergenceinduced ethylene synthesis in rice (Oryza sativa L.) J Exp Bot 58:1505–1514
Saftner R (1989) Effects of organic amines on α-aminoisobutyric acid uptake into the vacuole and
on ethylene production by tomato pericarp slices. Physiol Plant 75(4):485–491
From Aspartate to Ethylene: Central Role of N, C, and S Shuttles by. . .
289