Table 19.3 List of compounds that can serve as substrate and inhibitor for the enzyme ACC
deaminase
Compound
Substrate/
inhibitor
References
1-Aminocyclopropane-1-carboxylic
acid
Substrate Honma and Shimomura (1978);
Nascimento et al. (2014)
D-Vinylglycine
Substrate Honma and Shimomura (1978);
Nascimento et al. (2014)
β-Chloro-D-alanine
Substrate Fujino et al. (2004); Honma and
Shimomura (1978); Nascimento et al.
(2014); Walsh et al. (1981)
D-Cysteine
Substrate Fujino et al. (2004); Honma and
Shimomura (1978); Nascimento et al.
(2014); Walsh et al. (1981)
β-Fluoro-D-alanine
Substrate Fujino et al. (2004); Honma and
Shimomura (1978); Nascimento et al.
(2014); Walsh et al. (1981)
1-Amino-2-vinylcyclopropane-l-carboxylic acid
Substrate Fujino et al. (2004); Honma and
Shimomura (1978); Nascimento et al.
(2014); Walsh et al. (1981)
O-Acetyl-D-serine
Substrate Fujino et al. (2004); Honma and
Shimomura (1978); Nascimento et al.
(2014); Walsh et al. (1981)
β-Dichloro-D-alanine
Substrate Fujino et al. (2004); Honma and
Shimomura (1978); Nascimento et al.
(2014); Walsh et al. (1981)
β-Difluoro-D-alanine
Substrate Fujino et al. (2004); Honma and
Shimomura (1978); Nascimento et al.
(2014); Walsh et al. (1981)
3-Chloro-D-alanine
Substrate Fujino et al. (2004); Honma and
Shimomura (1978); Nascimento et al.
(2014); Walsh et al. (1981)
D-Erythro-2-amino-3-chlorobutyrate
Substrate Fujino et al. (2004); Honma and
Shimomura (1978); Nascimento et al.
(2014); Walsh et al. (1981)
D-Threo-2-amine-3-fluorobutyrate
Substrate Fujino et al. (2004); Honma and
Shimomura (1978); Nascimento et al.
(2014); Walsh et al. (1981)
D-Serine
Substrate Fujino et al. (2004); Honma and
Shimomura (1978); Nascimento et al.
(2014); Walsh et al. (1981)
L-Isomers of amino acids
Inhibitor
Fujino et al. (2004); Honma and
Shimomura (1978); Nascimento et al.
(2014); Walsh et al. (1981)
1-Amino-2-vinylcyclopropane-l-carboxylic acid
Substrate Singh et al. (2015)
1-Aminocyclopropane-1-phosphonate
Inhibitor
Karthikeyan et al. (2004)
Iodoacetamide derivative 1, 5
N-iodoacetamidoethyl
1-aminonapthalene-5-sulfonic acid
Inhibitor
Singh et al. (2015)
Iodoacetamide
Inhibitor
Singh et al. (2015)
376
S. Ali and B. R. Glick