42
which further convert to fusarinine C is a cyclic hexapeptide with the structure GlySer- Gly-(N5-acetyl-N5-hydroxyornithine)3 (Haas et  al. 2008). The siderophore
biosynthetic pathway is shown in Fig.  3.4. The primary step in the siderophore
biosynthesis involves the hydroxylation of ornithine catalyzed by the ornithine
Fig. 3.3 Common genes and protein targets in A. fumigatus and A. nidulans
Fig. 3.4 The siderophore biosynthetic pathway of A. fumigatus and A. nidulans. (Adapted from
Haas 2012)
S. Jayapalan et al.
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