195
Table 12.2 (continued)
Organisms
Associated Genes
Siderophores activity
Escherichia coli cueOyacK, b0123, JW0119
Blue copper oxidase CueO (copper
efflux oxidase)
Iron(3+)-hydroxamate-binding
protein FhuD (ferric hydroxamate
uptake protein D) (ferrichromebinding periplasmic protein)
(iron(III)-hydroxamate-binding
protein FhuD)
fhuD b0152, JW0148, LCN1, VEGP,
fiu Z1026, ECs0883, fiu c0890
Catecholate siderophore receptor Fiu
(ferric iron uptake protein) (TonBdependent receptor Fiu)
fiuybiL, b0805, JW0790
Neutrophil gelatinase-associated
lipocalin, NGAL (lipocalin-2)
(oncogene 24p3, 24p3) (SV-40induced 24p3 protein) (siderocalin
LCN2) (p25)
Lcn2
Lipocalin-1 (tear lipocalin, Tlc) (tear
prealbumin, TP) (von Ebner gland
protein, VEG protein)
Fiu UTI89_C0808
Siderophore export accessory protein
MmpS4 (PGB14T-X)
mmpS4 Rv0451c, MTV037.15c
ABC-type cobalamin/Fe3 + −
siderophores transport systems,
ATPase components
entF
Enterobactin synthase subunit F, EC 2.7.7.Staphylococcus
aureus
fepG NCTC13131_02773,
feuB_2 NCTC13131_04898,
fecD_1 NCTC7887_00508,
feuC_2 NCTC13131_04897,
fecD_2 NCTC7887_00509
Cobalamin Fe3 + −siderophores
ABC transporter
Permease
Saccharomyces
cerevisiae
FRE1 YLR214W, L8167.2,
CFL1 FRE1, CAALFM_C405770CA,
CaO19.1263, CaO19.8848
Ferric/cupric reductase
transmembrane component 1
FRE2 YKL220C
Ferric/cupric reductase
transmembrane component 2
FRE3 YOR381W, O6754
Ferric reductase transmembrane
component 3
FIT1 YDR534C, D9719.37
Facilitator of iron transport 1
FRE5 YOR384W, O6765
Ferric reductase transmembrane
component 5
(continued)
12 A Summary on Up-To-Date Research on Fungal Siderophores on Disease…