173
104. Shen, Y. H., Shoichet, M. S., & Radisic, M. (2008). Vascular endothelial growth factor immobilized in collagen scaffold promotes penetration and proliferation of endothelial cells. Acta
Biomaterialia, 4(3), 477–489. https://doi.org/10.1016/j.actbio.2007.12.011
105. Shen, Y. I., Cho, H., Papa, A. E., Burke, J. A., Chan, X. Y., Duh, E. J., et al. (2016). Engineered
human vascularized constructs accelerate diabetic wound healing. Biomaterials, 102, 107–119.
https://doi.org/10.1016/j.biomaterials.2016.06.009
106. Shimko, V. F., & Claycomb, W. C. (2008). Effect of mechanical loading on three-dimensional
cultures of embryonic stem cell-derived cardiomyocytes. Tissue Engineering. Part A, 14(1),
49–58. https://doi.org/10.1089/ten.a.2007.0092
107. Sieminski, A. L., Hebbel, R. P., & Gooch, K. J. (2004). The relative magnitudes of endothelial force generation and matrix stiffness modulate capillary morphogenesis in vitro.
Experimental Cell Research, 297(2), 574–584. https://doi.org/10.1016/j.yexcr.2004.03.035
108. Sinha, R., Le Gac, S., Verdonschot, N., Van Den Berg, A., Koopman, B., & Rouwkema, J.
(2016). Endothelial cell alignment as a result of anisotropic strain and flow induced shear
stress combinations. Scientific Reports, 6, 29510. https://doi.org/10.1038/srep29510
109. Souders, C. A., Bowers, S. L. K., & Baudino, T. A. (2009). Cardiac fibroblast: The
renaissance cell. Circulation Research, 105(12), 1164–1176. https://doi.org/10.1161/
CIRCRESAHA.109.209809
110. Steffens, G. C. M., Yao, C., Prével, P., Markowicz, M., Schenck, P., Noah, E. M., et al. (2004).
Modulation of angiogenic potential of collagen matrices by covalent incorporation of heparin
and loading with vascular endothelial growth factor. Tissue Engineering, 10(9-10), 1502–
1509. https://doi.org/10.1089/ten.2004.10.1502
111. Stevens, K. R., Kreutziger, K. L., Dupras, S. K., Korte, F. S., Regnier, M., Muskheli, V., et al.
(2009). Physiological function and transplantation of scaffold-free and vascularized human.
Proceedings of the National Academy of Sciences of the United States of America, 106(39),
16568.
112. Sun, X., & Nunes, S. S.. (2017). Maturation of human stem cell-derived cardiomyocytes
in biowires using electrical stimulation. Journal of Visualized Experiments, (123), 1–8.
doi:https://doi.org/10.3791/55373.
113. Sun, X., & Nunes, S. S. (2017). Bioengineering approaches to mature human pluripotent
stem cell-derived cardiomyocytes. Frontiers in Cell and Development Biology, 5, 19. https://
doi.org/10.3389/fcell.2017.00019
114. Taber, L. A. (1998). Mechanical aspects of cardiac development. Progress in Biophysics and
Molecular Biology, 69, 237–255.
115. Tandon, N., Cannizzaro, C., Chao, P.-H. G., Maidhof, R., Marsano, A., Au, H. T., et al.
(2009). Electrical stimulation systems for cardiac tissue engineering. Nature Protocols, 4(2),
155–173. https://doi.org/10.1038/nprot.2008.183
116. Thompson, S. A., Copeland, C. R., Reich, D. H., & Tung, L. (2011). Mechanical coupling between myofibroblasts and cardiomyocytes slows electric conduction in
fibrotic cell monolayers. Circulation, 123(19), 2083–2093. https://doi.org/10.1161/
CIRCULATIONAHA.110.015057
117. Thomson, K. S., Korte, F. S., Giachelli, C. M., Ratner, B. D., Regnier, M., & Scatena, M.
(2013). Prevascularized microtemplated fibrin scaffolds for cardiac tissue engineering
applications. Tissue Engineering. Part A, 19(7-8), 967–977. https://doi.org/10.1089/ten.
tea.2012.0286
118. Topper, J. N., & Gimbrone Jr., M. A. (1999). Blood flow and vascular gene expression:
Fluid shear stress as a modulator of endothelial phenotype. Molecular Medicine Today, 5(1),
40–46. https://doi.org/10.1016/S1357-4310(98)01372-0
119. Tulloch, N. L., Muskheli, V., Razumova, M. V., Korte, F. S., Regnier, M., Hauch, K.
D., et al. (2011). Growth of engineered human myocardium with mechanical loading and vascular Coculture. Circulation Research, 109, 47–59. https://doi.org/10.1161/
CIRCRESAHA.110.237206
6 Strategies for Tissue Engineering Vascularized Cardiac Patches to Treat Myocardial…
104. Shen, Y. H., Shoichet, M. S., & Radisic, M. (2008). Vascular endothelial growth factor immobilized in collagen scaffold promotes penetration and proliferation of endothelial cells. Acta
Biomaterialia, 4(3), 477–489. https://doi.org/10.1016/j.actbio.2007.12.011
105. Shen, Y. I., Cho, H., Papa, A. E., Burke, J. A., Chan, X. Y., Duh, E. J., et al. (2016). Engineered
human vascularized constructs accelerate diabetic wound healing. Biomaterials, 102, 107–119.
https://doi.org/10.1016/j.biomaterials.2016.06.009
106. Shimko, V. F., & Claycomb, W. C. (2008). Effect of mechanical loading on three-dimensional
cultures of embryonic stem cell-derived cardiomyocytes. Tissue Engineering. Part A, 14(1),
49–58. https://doi.org/10.1089/ten.a.2007.0092
107. Sieminski, A. L., Hebbel, R. P., & Gooch, K. J. (2004). The relative magnitudes of endothelial force generation and matrix stiffness modulate capillary morphogenesis in vitro.
Experimental Cell Research, 297(2), 574–584. https://doi.org/10.1016/j.yexcr.2004.03.035
108. Sinha, R., Le Gac, S., Verdonschot, N., Van Den Berg, A., Koopman, B., & Rouwkema, J.
(2016). Endothelial cell alignment as a result of anisotropic strain and flow induced shear
stress combinations. Scientific Reports, 6, 29510. https://doi.org/10.1038/srep29510
109. Souders, C. A., Bowers, S. L. K., & Baudino, T. A. (2009). Cardiac fibroblast: The
renaissance cell. Circulation Research, 105(12), 1164–1176. https://doi.org/10.1161/
CIRCRESAHA.109.209809
110. Steffens, G. C. M., Yao, C., Prével, P., Markowicz, M., Schenck, P., Noah, E. M., et al. (2004).
Modulation of angiogenic potential of collagen matrices by covalent incorporation of heparin
and loading with vascular endothelial growth factor. Tissue Engineering, 10(9-10), 1502–
1509. https://doi.org/10.1089/ten.2004.10.1502
111. Stevens, K. R., Kreutziger, K. L., Dupras, S. K., Korte, F. S., Regnier, M., Muskheli, V., et al.
(2009). Physiological function and transplantation of scaffold-free and vascularized human.
Proceedings of the National Academy of Sciences of the United States of America, 106(39),
16568.
112. Sun, X., & Nunes, S. S.. (2017). Maturation of human stem cell-derived cardiomyocytes
in biowires using electrical stimulation. Journal of Visualized Experiments, (123), 1–8.
doi:https://doi.org/10.3791/55373.
113. Sun, X., & Nunes, S. S. (2017). Bioengineering approaches to mature human pluripotent
stem cell-derived cardiomyocytes. Frontiers in Cell and Development Biology, 5, 19. https://
doi.org/10.3389/fcell.2017.00019
114. Taber, L. A. (1998). Mechanical aspects of cardiac development. Progress in Biophysics and
Molecular Biology, 69, 237–255.
115. Tandon, N., Cannizzaro, C., Chao, P.-H. G., Maidhof, R., Marsano, A., Au, H. T., et al.
(2009). Electrical stimulation systems for cardiac tissue engineering. Nature Protocols, 4(2),
155–173. https://doi.org/10.1038/nprot.2008.183
116. Thompson, S. A., Copeland, C. R., Reich, D. H., & Tung, L. (2011). Mechanical coupling between myofibroblasts and cardiomyocytes slows electric conduction in
fibrotic cell monolayers. Circulation, 123(19), 2083–2093. https://doi.org/10.1161/
CIRCULATIONAHA.110.015057
117. Thomson, K. S., Korte, F. S., Giachelli, C. M., Ratner, B. D., Regnier, M., & Scatena, M.
(2013). Prevascularized microtemplated fibrin scaffolds for cardiac tissue engineering
applications. Tissue Engineering. Part A, 19(7-8), 967–977. https://doi.org/10.1089/ten.
tea.2012.0286
118. Topper, J. N., & Gimbrone Jr., M. A. (1999). Blood flow and vascular gene expression:
Fluid shear stress as a modulator of endothelial phenotype. Molecular Medicine Today, 5(1),
40–46. https://doi.org/10.1016/S1357-4310(98)01372-0
119. Tulloch, N. L., Muskheli, V., Razumova, M. V., Korte, F. S., Regnier, M., Hauch, K.
D., et al. (2011). Growth of engineered human myocardium with mechanical loading and vascular Coculture. Circulation Research, 109, 47–59. https://doi.org/10.1161/
CIRCRESAHA.110.237206
6 Strategies for Tissue Engineering Vascularized Cardiac Patches to Treat Myocardial…