94. D. Kirchenbuechler, Y. Mutsafi, B. Horowitz, D. Fass, S.G. Wolf, M. Elbaum, Cryo-STEM
tomography of intact vitrified fibroblasts. AIMS Biophys. 2(3), 259–273 (2015). doi:10.
3934/biophy.2015.3.259
95. D. Charuvi, V. Kiss, R. Nevo, E. Shimoni, Z. Adam, Z. Reich, Gain and loss of photosynthetic
membranes during plastid differentiation in the shoot apex of Arabidopsis. Plant Cell 24(3),
1143–1157 (2012). doi:10.1105/tpc.111.094458
96. S. Kapishnikov, A. Weiner, E. Shimoni, P. Guttmann, G. Schneider, N. Dahan-Pasternak, R.
Dzikowski, L. Leiserowitz, M. Elbaum, Oriented nucleation of hemozoin at the digestive
vacuole membrane in Plasmodium falciparum. Proc. Natl. Acad. Sci. U S A 109(28), 11188–
11193 (2012). doi:10.1073/pnas.1118120109
97. Y. Mutsafi, E. Shimoni, A. Shimon, A. Minsky, Membrane assembly during the infection
cycle of the giant mimivirus. PLoS Pathog. 9(5), e1003367 (2013). doi:10.1371/journal.ppat.
1003367
98. O. Tsabari, R. Nevo, S. Meir, L.R. Carrillo, D.M. Kramer, Z. Reich, Differential effects of
ambient or diminished CO2 and O2 levels on thylakoid membrane structure in light-stressed
plants. Plant J. 81(6), 884–894 (2015). doi:10.1111/tpj.12774
99. E. Milrot, Y. Mutsafi, Y. Fridmann-Sirkis, E. Shimoni, K. Rechav, J.R. Gurnon, J.L. Van
Etten, A. Minsky, Virus–host interactions: insights from the replication cycle of the large
Paramecium bursaria chlorella virus. Cell. Microbiol. 18(1), 3–16 (2016). doi:10.1111/cmi.
12486
100. E. Kennedy, E.M. Nelson, T. Tanaka, J. Damiano, G. Timp, Live bacterial physiology
visualized with 5 nm resolution using scanning transmission electron microscopy. ACS
Nano 10(2), 2669–2677 (2016). doi:10.1021/acsnano.5b07697
101. Nd Jonge, D.B. Peckys, G.J. Kremers, D.W. Piston, Electron microscopy of whole cells in
liquid with nanometer resolution. Proc. Natl. Acad. Sci. 106(7), 2159–2164 (2009). doi:10.
1073/pnas.0809567106
102. S. Kapishnikov, A. Weiner, E. Shimoni, G. Schneider, M. Elbaum, L. Leiserowitz, Digestive
vacuole membrane in Plasmodium falciparum-infected erythrocytes: relevance to templated
nucleation of hemozoin. Langmuir: ACS J. Surf. Colloids 29(47), 14595–14602 (2013).
doi:10.1021/la402545c
103. E.A. Smith, B.P. Cinquin, M. Do, G. McDermott, M.A. Le Gros, C.A. Larabell, Correlative
cryogenic tomography of cells using light and soft x-rays. Ultramicroscopy 143, 33–40
(2014). doi:10.1016/j.ultramic.2013.10.013
104. E. Duke, K. Dent, M. Razi, L.M. Collinson, Biological applications of cryo-soft X-ray
tomography. J. Microsc. 255(2), 65–70 (2014). doi:10.1111/jmi.12139
105. A. Schertel, N. Snaidero, H.M. Han, T. Ruhwedel, M. Laue, M. Grabenbauer, W. Mobius,
Cryo FIB-SEM: volume imaging of cellular ultrastructure in native frozen specimens.
J. Struct. Biol. 184(2), 355–360 (2013). doi:10.1016/j.jsb.2013.09.024
106. N. Vidavsky, A. Masic, A. Schertel, S. Weiner, L. Addadi, Mineral-bearing vesicle transport
in sea urchin embryos. J. Struct. Biol. 192(3), 358–365 (2015). doi:10.1016/j.jsb.2015.09.
017
107. S. Sviben, A. Gal, M.A. Hood, L. Bertinetti, Y. Politi, M. Bennet, P. Krishnamoorthy, A.
Schertel, R. Wirth, A. Sorrentino, E. Pereiro, D. Faivre, A. Scheffel, A vacuole-like
compartment concentrates a disordered calcium phase in a key coccolithophorid alga. Nat.
Commun. 7 (2016). doi:10.1038/ncomms11228
108. J.R. Kremer, D.N. Mastronarde, J.R. McIntosh, Computer visualization of three-dimensional
image data using IMOD. J. Struct. Biol. 116(1), 71–76 (1996). doi:10.1006/jsbi.1996.0013
109. J.-I. Agulleiro, J.-J. Fernandez, Tomo3D 2.0—Exploitation of Advanced Vector eXtensions
(AVX) for 3D reconstruction. J. Struct. Biol. 189(2), 147–152 (2015). doi:http://dx.doi.org/
10.1016/j.jsb.2014.11.009
110. C. MessaoudiI, T. Boudier, C.O.S. Sorzano, S. Marco, TomoJ: tomography software for
three-dimensional reconstruction in transmission electron microscopy. BMC Bioinformatics
8(1), 1–9 (2007). doi:10.1186/1471-2105-8-288
60
S. G. Wolf et al.
tomography of intact vitrified fibroblasts. AIMS Biophys. 2(3), 259–273 (2015). doi:10.
3934/biophy.2015.3.259
95. D. Charuvi, V. Kiss, R. Nevo, E. Shimoni, Z. Adam, Z. Reich, Gain and loss of photosynthetic
membranes during plastid differentiation in the shoot apex of Arabidopsis. Plant Cell 24(3),
1143–1157 (2012). doi:10.1105/tpc.111.094458
96. S. Kapishnikov, A. Weiner, E. Shimoni, P. Guttmann, G. Schneider, N. Dahan-Pasternak, R.
Dzikowski, L. Leiserowitz, M. Elbaum, Oriented nucleation of hemozoin at the digestive
vacuole membrane in Plasmodium falciparum. Proc. Natl. Acad. Sci. U S A 109(28), 11188–
11193 (2012). doi:10.1073/pnas.1118120109
97. Y. Mutsafi, E. Shimoni, A. Shimon, A. Minsky, Membrane assembly during the infection
cycle of the giant mimivirus. PLoS Pathog. 9(5), e1003367 (2013). doi:10.1371/journal.ppat.
1003367
98. O. Tsabari, R. Nevo, S. Meir, L.R. Carrillo, D.M. Kramer, Z. Reich, Differential effects of
ambient or diminished CO2 and O2 levels on thylakoid membrane structure in light-stressed
plants. Plant J. 81(6), 884–894 (2015). doi:10.1111/tpj.12774
99. E. Milrot, Y. Mutsafi, Y. Fridmann-Sirkis, E. Shimoni, K. Rechav, J.R. Gurnon, J.L. Van
Etten, A. Minsky, Virus–host interactions: insights from the replication cycle of the large
Paramecium bursaria chlorella virus. Cell. Microbiol. 18(1), 3–16 (2016). doi:10.1111/cmi.
12486
100. E. Kennedy, E.M. Nelson, T. Tanaka, J. Damiano, G. Timp, Live bacterial physiology
visualized with 5 nm resolution using scanning transmission electron microscopy. ACS
Nano 10(2), 2669–2677 (2016). doi:10.1021/acsnano.5b07697
101. Nd Jonge, D.B. Peckys, G.J. Kremers, D.W. Piston, Electron microscopy of whole cells in
liquid with nanometer resolution. Proc. Natl. Acad. Sci. 106(7), 2159–2164 (2009). doi:10.
1073/pnas.0809567106
102. S. Kapishnikov, A. Weiner, E. Shimoni, G. Schneider, M. Elbaum, L. Leiserowitz, Digestive
vacuole membrane in Plasmodium falciparum-infected erythrocytes: relevance to templated
nucleation of hemozoin. Langmuir: ACS J. Surf. Colloids 29(47), 14595–14602 (2013).
doi:10.1021/la402545c
103. E.A. Smith, B.P. Cinquin, M. Do, G. McDermott, M.A. Le Gros, C.A. Larabell, Correlative
cryogenic tomography of cells using light and soft x-rays. Ultramicroscopy 143, 33–40
(2014). doi:10.1016/j.ultramic.2013.10.013
104. E. Duke, K. Dent, M. Razi, L.M. Collinson, Biological applications of cryo-soft X-ray
tomography. J. Microsc. 255(2), 65–70 (2014). doi:10.1111/jmi.12139
105. A. Schertel, N. Snaidero, H.M. Han, T. Ruhwedel, M. Laue, M. Grabenbauer, W. Mobius,
Cryo FIB-SEM: volume imaging of cellular ultrastructure in native frozen specimens.
J. Struct. Biol. 184(2), 355–360 (2013). doi:10.1016/j.jsb.2013.09.024
106. N. Vidavsky, A. Masic, A. Schertel, S. Weiner, L. Addadi, Mineral-bearing vesicle transport
in sea urchin embryos. J. Struct. Biol. 192(3), 358–365 (2015). doi:10.1016/j.jsb.2015.09.
017
107. S. Sviben, A. Gal, M.A. Hood, L. Bertinetti, Y. Politi, M. Bennet, P. Krishnamoorthy, A.
Schertel, R. Wirth, A. Sorrentino, E. Pereiro, D. Faivre, A. Scheffel, A vacuole-like
compartment concentrates a disordered calcium phase in a key coccolithophorid alga. Nat.
Commun. 7 (2016). doi:10.1038/ncomms11228
108. J.R. Kremer, D.N. Mastronarde, J.R. McIntosh, Computer visualization of three-dimensional
image data using IMOD. J. Struct. Biol. 116(1), 71–76 (1996). doi:10.1006/jsbi.1996.0013
109. J.-I. Agulleiro, J.-J. Fernandez, Tomo3D 2.0—Exploitation of Advanced Vector eXtensions
(AVX) for 3D reconstruction. J. Struct. Biol. 189(2), 147–152 (2015). doi:http://dx.doi.org/
10.1016/j.jsb.2014.11.009
110. C. MessaoudiI, T. Boudier, C.O.S. Sorzano, S. Marco, TomoJ: tomography software for
three-dimensional reconstruction in transmission electron microscopy. BMC Bioinformatics
8(1), 1–9 (2007). doi:10.1186/1471-2105-8-288
60
S. G. Wolf et al.
