Contents
Biophysical Characterization of Aptamer-Target Interactions . . . . . . . .
1
Maximilian Plach and Thomas Schubert
Impedimetric Aptamer-Based Biosensors: Principles and Techniques . . 17
Peggy Reich, John-Alexander Preuß, Nicole Bahner,
and Janina Bahnemann
Impedimetric Aptamer-Based Biosensors: Applications . . . . . . . . . . . . . 43
John-Alexander Preuß, Peggy Reich, Nicole Bahner,
and Janina Bahnemann
Aptamer-Based Affinity Chromatography for Protein Extraction and
Purification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93
G. Perret and E. Boschetti
Aptamers in Diagnostic and Molecular Imaging Applications . . . . . . . . 141
Victoria Calzada
Aptamer-Modified Nanoparticles in Medical Applications . . . . . . . . . . . 161
Alina Eilers, Sandra Witt, and Johanna Walter
Defining Target Product Profiles (TPPs) for Aptamer-Based
Diagnostics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195
Harleen Kaur, Bandhan Chaterjee, John G. Bruno,
and Tarun Kumar Sharma
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 211
vii
Biophysical Characterization of Aptamer-Target Interactions . . . . . . . .
1
Maximilian Plach and Thomas Schubert
Impedimetric Aptamer-Based Biosensors: Principles and Techniques . . 17
Peggy Reich, John-Alexander Preuß, Nicole Bahner,
and Janina Bahnemann
Impedimetric Aptamer-Based Biosensors: Applications . . . . . . . . . . . . . 43
John-Alexander Preuß, Peggy Reich, Nicole Bahner,
and Janina Bahnemann
Aptamer-Based Affinity Chromatography for Protein Extraction and
Purification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93
G. Perret and E. Boschetti
Aptamers in Diagnostic and Molecular Imaging Applications . . . . . . . . 141
Victoria Calzada
Aptamer-Modified Nanoparticles in Medical Applications . . . . . . . . . . . 161
Alina Eilers, Sandra Witt, and Johanna Walter
Defining Target Product Profiles (TPPs) for Aptamer-Based
Diagnostics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195
Harleen Kaur, Bandhan Chaterjee, John G. Bruno,
and Tarun Kumar Sharma
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 211
vii
