Abstract Impedimetric aptamer-based biosensors show high potential for handheld
devices and point-of-care tests. In this review, we report on recent advances in
aptamer-based impedimetric biosensors for applications in biotechnology. We detail
on analytes relevant in medical and environmental biotechnology as well as food
control, for which aptamer-based impedimetric biosensors were developed. The
reviewed biosensors are examined for their performance, including sensitivity,
selectivity, response time, and real sample validation. Additionally, the benefits
and challenges of impedimetric aptasensors are summarized.
Graphical Abstract
Keywords Aptamer, Aptasensor, Bacteria, Biomarker, Biosensor, Cancer,
Contaminants, Diagnostics, Disease, Drug, Environmental, Food industry, Health
care, Impedance, Infection, Monitoring, Pathogen, Point-of-care, Serum, Therapy,
Toxins, Tumor marker, Virus
44
J.-A. Preuß et al.
devices and point-of-care tests. In this review, we report on recent advances in
aptamer-based impedimetric biosensors for applications in biotechnology. We detail
on analytes relevant in medical and environmental biotechnology as well as food
control, for which aptamer-based impedimetric biosensors were developed. The
reviewed biosensors are examined for their performance, including sensitivity,
selectivity, response time, and real sample validation. Additionally, the benefits
and challenges of impedimetric aptasensors are summarized.
Graphical Abstract
Keywords Aptamer, Aptasensor, Bacteria, Biomarker, Biosensor, Cancer,
Contaminants, Diagnostics, Disease, Drug, Environmental, Food industry, Health
care, Impedance, Infection, Monitoring, Pathogen, Point-of-care, Serum, Therapy,
Toxins, Tumor marker, Virus
44
J.-A. Preuß et al.