158
E. A. Thompson
Li H, Durbin R (2011) Inference of human population history from individual whole-genome
sequences. Nature 475:493–496
McPeek MS (1999) Optimal allele-sharing statistics for genetic mapping using affected relatives.
Genet Epidemiol 16:225–249
Mendel G (1866) Experiments in plant hybridisation. In: Bennett JH (ed) English translation and
commentary by R. A. Fisher. Oliver and Boyd, Edinburgh, 1965
Moltke I, Albrechtsen A, Hansen T, Nielsen FC, Nielsen R (2011) A method for detecting IBD
regions simultaneously in multiple individuals – with applications to disease genetics. Genome
Res 21:1168–1180
Morton NE (1955) Sequential tests for the detection of linkage. Am J Hum Genet 7:277–318
Peter B, Wijsman EM, Nato AQ Jr, Matsushita M, Chapman KL, Stanaway IB, Wolff J, Oda K,
Gabo VB, Raskind WH (2016) Genetic candidate variants in two multigenerational families
with childhood apraxia of speech. PLOS One 11(4):e0153864
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D (2006) Principal
components analysis corrects for stratification in genome-wide association studies. Nat Genet
38:904–909
Saad M, Nato AQ, Grimson FL, Leweis SM, Brown L, Blue EM, Thornton TA, Thompson
EA, Wijsman EM (2016) Identity-by-descent estimation with population- and pedigree-based
imputation in admixed family data. BMC Proc 10(Suppl 7):295–301
Smith CAB (1953) Detection of linkage in human genetics. J Roy Stat Soc B 15:153–192
Sobel E, Lange K (1996) Descent graphs in pedigree analysis: applications to haplotyping, location
scores, and marker-sharing statistics. Am J Hum Genet 58:1323–1337
Speed D, Hemani G, Johnson MR, Balding DJ (2012) Improved heritability estimation from
genome-wide SNPs. Am J Hum Genet 91:1011–1021
Su M, Thompson EA (2012) Computationally efficient multipoint linkage analysis on extended
pedigrees for trait models with two contributing major loci. Genet Epidemiol 38:602–611
Suarez BK, Rice J, Reich T (1978) The generalized sib pair IBD distribution: its use in the detection
of linkage. Ann Hum Genet 42:87–94
Tavaré S, Ewens WJ (1997) The multivariate Ewens distribution. In: Discrete multivariate
distributions. Wiley, New York, pp 232–246
Thompson EA (2000) Statistical inferences from genetic data on pedigrees. In: Volume 6 of
NSF-CBMS regional conference series in probability and statistics. Institute of Mathematical
Statistics, Beachwood
Thompson EA (2019) Descent-based gene mapping in pedigrees and populations, chapter 20. In:
Balding DJ, Moltke I, Marioni J (eds) Handbook of statistical genomics, 4th edn. Wiley, Oxford,
UK, pp 573–596
VanRaden PM (2008) Efficient methods to compute genomic predictions. J Dairy Sci 91:4414–
4423
Wang B, Sverdlov S, Thompson EA (2017) Efficient estimation of realized kinship. Genetics
205:1063–1078
Weeks DE, Lange K (1988) The affected pedigree member method of linkage analysis. Am J Hum
Genet 42:315–326
Zheng C, Kuhner MK, Thompson EA (2014) Joint inference of identity by descent along multiple
chromosomes from population samples. J Comput Biol 21:185–200
E. A. Thompson
Li H, Durbin R (2011) Inference of human population history from individual whole-genome
sequences. Nature 475:493–496
McPeek MS (1999) Optimal allele-sharing statistics for genetic mapping using affected relatives.
Genet Epidemiol 16:225–249
Mendel G (1866) Experiments in plant hybridisation. In: Bennett JH (ed) English translation and
commentary by R. A. Fisher. Oliver and Boyd, Edinburgh, 1965
Moltke I, Albrechtsen A, Hansen T, Nielsen FC, Nielsen R (2011) A method for detecting IBD
regions simultaneously in multiple individuals – with applications to disease genetics. Genome
Res 21:1168–1180
Morton NE (1955) Sequential tests for the detection of linkage. Am J Hum Genet 7:277–318
Peter B, Wijsman EM, Nato AQ Jr, Matsushita M, Chapman KL, Stanaway IB, Wolff J, Oda K,
Gabo VB, Raskind WH (2016) Genetic candidate variants in two multigenerational families
with childhood apraxia of speech. PLOS One 11(4):e0153864
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D (2006) Principal
components analysis corrects for stratification in genome-wide association studies. Nat Genet
38:904–909
Saad M, Nato AQ, Grimson FL, Leweis SM, Brown L, Blue EM, Thornton TA, Thompson
EA, Wijsman EM (2016) Identity-by-descent estimation with population- and pedigree-based
imputation in admixed family data. BMC Proc 10(Suppl 7):295–301
Smith CAB (1953) Detection of linkage in human genetics. J Roy Stat Soc B 15:153–192
Sobel E, Lange K (1996) Descent graphs in pedigree analysis: applications to haplotyping, location
scores, and marker-sharing statistics. Am J Hum Genet 58:1323–1337
Speed D, Hemani G, Johnson MR, Balding DJ (2012) Improved heritability estimation from
genome-wide SNPs. Am J Hum Genet 91:1011–1021
Su M, Thompson EA (2012) Computationally efficient multipoint linkage analysis on extended
pedigrees for trait models with two contributing major loci. Genet Epidemiol 38:602–611
Suarez BK, Rice J, Reich T (1978) The generalized sib pair IBD distribution: its use in the detection
of linkage. Ann Hum Genet 42:87–94
Tavaré S, Ewens WJ (1997) The multivariate Ewens distribution. In: Discrete multivariate
distributions. Wiley, New York, pp 232–246
Thompson EA (2000) Statistical inferences from genetic data on pedigrees. In: Volume 6 of
NSF-CBMS regional conference series in probability and statistics. Institute of Mathematical
Statistics, Beachwood
Thompson EA (2019) Descent-based gene mapping in pedigrees and populations, chapter 20. In:
Balding DJ, Moltke I, Marioni J (eds) Handbook of statistical genomics, 4th edn. Wiley, Oxford,
UK, pp 573–596
VanRaden PM (2008) Efficient methods to compute genomic predictions. J Dairy Sci 91:4414–
4423
Wang B, Sverdlov S, Thompson EA (2017) Efficient estimation of realized kinship. Genetics
205:1063–1078
Weeks DE, Lange K (1988) The affected pedigree member method of linkage analysis. Am J Hum
Genet 42:315–326
Zheng C, Kuhner MK, Thompson EA (2014) Joint inference of identity by descent along multiple
chromosomes from population samples. J Comput Biol 21:185–200