specialized. Thus, different cell types need different genes in the whole genome to fulfill
their job within the body or to build certain structures. Consequently, the human genome
has a kind of switch on/off mechanism. Genes, which are needed are transcribed and those,
which are not needed are not. To regulate this, on the one hand, regulatory sequences can
be found in the genome, like silencer, enhancer, promoter regions. On the other hand,
epigenetic mechanism can influence gene expression and thus protein production.
Fig. 1.4 From DNA to RNA to Proteins. Cellular structures for sequencing applications. (source:
# Melanie Kappelmann-Fenzl)
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A. Bosserhoff and M. Kappelmann-Fenzl
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