Kumar V, Jain M (2015) The CRISPR-Cas system for plant genome editing: advances and
opportunities. J Exp Bot 66:47–57
Kumar S, Hahn FM, Baidoo E, Kahlon TS, Wood DF, McMahan CM, Cornish K, Keasling JD,
Daniell H, Whalen MC (2012) Remodeling the isoprenoid pathway in tobacco by expressing the
cytoplasmic mevalonate pathway in chloroplasts. Metab Eng 14:19–28
Lagarde F, Jaffrezic-Renault N (2011) Cell-based electrochemical biosensors for water quality
assessment. Anal Bioanal Chem 400:947–964
Lartigue C, Glass JI, Alperovich N, Pieper R, Parmar PP, Hutchison CA III, Smith HO, Venter JC
(2007) Genome transplantation in bacteria: changing one species to another. Science
317:632–638
Laursen T, Borch J, Knudsen C et al (2016) Characterization of a dynamic metabolon producing the
defense compound dhurrin in sorghum. Science 354(6314):890–893
Le Quere C, Raupach MR, Canadell JG et al (2009) Trends in the sources and sinks of carbon
dioxide. Nat Geosci 2:831–836
Lee D, Lloyd NDR, Pretorius IS, Borneman AR (2016) Heterologous production of raspberry
ketone in the wine yeast Saccharomyces cerevisiae via pathway engineering and synthetic
enzyme fusion. Microb Cell Factories 15:49
Lee KY, Park S-J, Lee KA, Kim S-H, Kim H, Meroz Y, Mahadevan L, Jung K-H, Ahn TK, Parker
KK, Shin K (2018) Photosynthetic artificial organelles sustain and control ATP-dependent
reactions in a protocellular system. Nat Biotechnol 36:530–535
Leister D (2019) Genetic engineering, synthetic biology and the light reactions of photosynthesis.
Plant Physiol 179(3):778–793
Li Q, Song J, Peng S, Wang JP, Qu GZ, Sederoff RR, Chiang VL (2014) Plant biotechnology for
lignocellulosic biofuel production. Plant Biotechnol J 12:1174–1192
Li J, Meng X, Zong Y et al (2016) Gene replacements and insertions in rice by intron targeting using
CRISPR–Cas9. Nat Plants 2:16139
Li P, Li YJ, Zhang FJ et al (2017) The Arabidopsis UDP-glycosyltransferases UGT79B2 and
UGT79B3, contribute to cold, salt and drought stress tolerance via modulating anthocyanin
accumulation. Plant J 89(1):85–103
Li S, Li Y, Smolke CD (2018) Strategies for microbial synthesis of high-value phytochemicals. Nat
Chem 10(4):395–404
Lin MT, Occhialini A, Andralojc PJ, Devonshire J, Hines KM, Parry MAJ, Hanson MR (2014)
β-carboxysomal proteins assemble into highly organized structures in Nicotiana chloroplasts.
Plant J 79(1):1–12
Liu W, Stewart CN Jr (2015) Plant synthetic biology. Trends Plant Sci 20(5):309–317
Liu W, Mazarei M, Rudis MR, Fethe MH, Peng Y, Millwood RJ, Schoene G, Burris JN, Stewart
CN Jr (2013a) Bacterial pathogen phytosensing in transgenic tobacco and Arabidopsis. Plant
Biotechnol J 11:43–52
Liu W, Yuan JS, Stewart CN Jr (2013b) Advanced genetic tools for plant biotechnology. Nat Rev
Genet 14(11):781–793
Liu W, Mazarei M, Peng Y, Fethe MH, Rudis MR, Lin J, Millwood RJ, Arelli PR, Stewart CN Jr
(2014) Computational discovery of soybean promoter cis-regulatory elements for the construction of soybean cyst nematode inducible synthetic promoters. Plant Biotechnol J 12:1015–1026
Liu W, Luo Z, Wang Y, Pham NT, Tuck L, Pérez-Pi I, Liu L, Shen Y, French C, Auer M, MarlesWright J, Dai J, Cai Y (2018a) Rapid pathway prototyping and engineering using in vitro and
in vivo synthetic genome SCRaMbLE-in methods. Nat Commun 9:1936
Liu D, Mannan AA, Han Y, Oyarzún DA, Zhang F (2018b) Dynamic metabolic control: towards
precision engineering of metabolism. J Ind Microbiol Biotechnol 45:535–543
Long SP, Zhu XG, Naidu SL, Ort DR (2006) Can improvement in photosynthesis increase crop
yields? Plant Cell Environ 29:315–330
Long SP, Marshall-Colon A, Zhu XG (2015) Meeting the global food demand of the future by
engineering crop photosynthesis and yield potential. Cell 161(1):56–66
480
P. Singla
opportunities. J Exp Bot 66:47–57
Kumar S, Hahn FM, Baidoo E, Kahlon TS, Wood DF, McMahan CM, Cornish K, Keasling JD,
Daniell H, Whalen MC (2012) Remodeling the isoprenoid pathway in tobacco by expressing the
cytoplasmic mevalonate pathway in chloroplasts. Metab Eng 14:19–28
Lagarde F, Jaffrezic-Renault N (2011) Cell-based electrochemical biosensors for water quality
assessment. Anal Bioanal Chem 400:947–964
Lartigue C, Glass JI, Alperovich N, Pieper R, Parmar PP, Hutchison CA III, Smith HO, Venter JC
(2007) Genome transplantation in bacteria: changing one species to another. Science
317:632–638
Laursen T, Borch J, Knudsen C et al (2016) Characterization of a dynamic metabolon producing the
defense compound dhurrin in sorghum. Science 354(6314):890–893
Le Quere C, Raupach MR, Canadell JG et al (2009) Trends in the sources and sinks of carbon
dioxide. Nat Geosci 2:831–836
Lee D, Lloyd NDR, Pretorius IS, Borneman AR (2016) Heterologous production of raspberry
ketone in the wine yeast Saccharomyces cerevisiae via pathway engineering and synthetic
enzyme fusion. Microb Cell Factories 15:49
Lee KY, Park S-J, Lee KA, Kim S-H, Kim H, Meroz Y, Mahadevan L, Jung K-H, Ahn TK, Parker
KK, Shin K (2018) Photosynthetic artificial organelles sustain and control ATP-dependent
reactions in a protocellular system. Nat Biotechnol 36:530–535
Leister D (2019) Genetic engineering, synthetic biology and the light reactions of photosynthesis.
Plant Physiol 179(3):778–793
Li Q, Song J, Peng S, Wang JP, Qu GZ, Sederoff RR, Chiang VL (2014) Plant biotechnology for
lignocellulosic biofuel production. Plant Biotechnol J 12:1174–1192
Li J, Meng X, Zong Y et al (2016) Gene replacements and insertions in rice by intron targeting using
CRISPR–Cas9. Nat Plants 2:16139
Li P, Li YJ, Zhang FJ et al (2017) The Arabidopsis UDP-glycosyltransferases UGT79B2 and
UGT79B3, contribute to cold, salt and drought stress tolerance via modulating anthocyanin
accumulation. Plant J 89(1):85–103
Li S, Li Y, Smolke CD (2018) Strategies for microbial synthesis of high-value phytochemicals. Nat
Chem 10(4):395–404
Lin MT, Occhialini A, Andralojc PJ, Devonshire J, Hines KM, Parry MAJ, Hanson MR (2014)
β-carboxysomal proteins assemble into highly organized structures in Nicotiana chloroplasts.
Plant J 79(1):1–12
Liu W, Stewart CN Jr (2015) Plant synthetic biology. Trends Plant Sci 20(5):309–317
Liu W, Mazarei M, Rudis MR, Fethe MH, Peng Y, Millwood RJ, Schoene G, Burris JN, Stewart
CN Jr (2013a) Bacterial pathogen phytosensing in transgenic tobacco and Arabidopsis. Plant
Biotechnol J 11:43–52
Liu W, Yuan JS, Stewart CN Jr (2013b) Advanced genetic tools for plant biotechnology. Nat Rev
Genet 14(11):781–793
Liu W, Mazarei M, Peng Y, Fethe MH, Rudis MR, Lin J, Millwood RJ, Arelli PR, Stewart CN Jr
(2014) Computational discovery of soybean promoter cis-regulatory elements for the construction of soybean cyst nematode inducible synthetic promoters. Plant Biotechnol J 12:1015–1026
Liu W, Luo Z, Wang Y, Pham NT, Tuck L, Pérez-Pi I, Liu L, Shen Y, French C, Auer M, MarlesWright J, Dai J, Cai Y (2018a) Rapid pathway prototyping and engineering using in vitro and
in vivo synthetic genome SCRaMbLE-in methods. Nat Commun 9:1936
Liu D, Mannan AA, Han Y, Oyarzún DA, Zhang F (2018b) Dynamic metabolic control: towards
precision engineering of metabolism. J Ind Microbiol Biotechnol 45:535–543
Long SP, Zhu XG, Naidu SL, Ort DR (2006) Can improvement in photosynthesis increase crop
yields? Plant Cell Environ 29:315–330
Long SP, Marshall-Colon A, Zhu XG (2015) Meeting the global food demand of the future by
engineering crop photosynthesis and yield potential. Cell 161(1):56–66
480
P. Singla