202
and a two-component regulatory system. Mol Microbiol 21:853–862. https://doi.
org/10.1046/j.1365-2958.1996.501417.x
Peters L, König GM, Wright AD, Pukall R, Stackebrandt E, Eberl L, Riedel K (2003) Secondary
metabolites of Flustra foliacea and their influence on bacteria. Appl Environ Microbiol
69:3469–3475. https://doi.org/10.1128/aem.69.6.3469-3475.2003
Pinkston KL, Gao P, Diaz-Garcia D, Sillanpää J, Nallapareddy SR, Murray BE, Harvey BR (2011)
The Fsr quorum-sensing system of Enterococcus faecalis modulates surface display of the
collagen-binding MSCRAMM ace through regulation of gelE. J Bacteriol 193:4317–4325.
https://doi.org/10.1128/JB.05026-11
Rajamani S, Bauer WD, Robinson JB, Farrow JM, Pesci EC, Teplitski M, Gao M, Sayre RT,
Phillips DA (2008) The vitamin riboflavin and its derivative Lumichrome activate the LasR
bacterial quorum-sensing receptor. Mol Plant-Microbe Interact 21:1184–1192. https://doi.
org/10.1094/MPMI-21-9-1184
Rajput A, Kaur K, Kumar M (2016) SigMol: repertoire of quorum-sensing signaling molecules in
prokaryotes. Nucleic Acids Res 44:D634–D639. https://doi.org/10.1093/nar/gkv1076
Rasmussen TB, Skindersoe ME, Bjarnsholt T, Phipps RK, Christensen KB, Jensen PO, Andersen
JB, Koch B, Larsen TO, Hentzer M, Eberl L, Hoiby N, Givskov M (2005) Identity and effects
of quorum-sensing inhibitors produced by Penicillium species. Microbiology 151:1325–1340.
https://doi.org/10.1099/mic.0.27715-0
Rémy B, Mion S, Plener L, Elias M, Chabrière E, Daudé D (2018) Interference in bacterial quorumsensing: a biopharmaceutical perspective. Front Pharmacol 9:203. https://doi.org/10.3389/
fphar.2018.00203
Rice SA, Givskov M, Høiby N, Parsek MR, Riedel K, Heydorn A, Eberl L, Andersen JB, Hentzer
M, Molin S, Kjelleberg S, Rasmussen TB (2002) Inhibition of quorum-sensing in Pseudomonas
aeruginosa biofilm bacteria by a halogenated furanone compound. Microbiology 148:87–102.
https://doi.org/10.1099/00221287-148-1-87
Rutherford ST, Bassler BL (2012) Bacterial quorum-sensing: its role in virulence and possibilities for its control. Cold Spring Harb Perspect Med 2:a012427. https://doi.org/10.1101/
CSHPERSPECT.A012427
Saiman L, Marshall BC, Mayer-Hamblett N, Burns JL, Quittner AL, Cibene DA, Coquillette S,
Fieberg AY, Accurso FJ, Campbell III PW, for the Macrolide Study Group (2003) Azithromycin
in patients with cystic fibrosis chronically infected with Pseudomonas aeruginosa. JAMA
290:1749. https://doi.org/10.1001/jama.290.13.1749
Seed PC, Passador L, Iglewski BH (1995) Activation of the Pseudomonas aeruginosa lasI gene by
LasR and the Pseudomonas autoinducer PAI: an autoinduction regulatory hierarchy. J Bacteriol
177:654–659. https://doi.org/10.1128/jb.177.3.654-659.1995
Shankar J, Walker RG, Ward D, Horsburgh MJ (2012) The enterococcus faecalis exoproteome:
identification and temporal regulation by fsr. PLoS One 7. https://doi.org/10.1371/journal.
pone.0033450
Shih P-C, Huang C-T (2002) Effects of quorum-sensing deficiency on Pseudomonas aeruginosa
biofilm formation and antibiotic resistance. J Antimicrob Chemother 49:309–314. https://doi.
org/10.1093/jac/49.2.309
Sifri CD, Mylonakis E, Singh KV, Qin X, Garsin DA, Murray BE, Ausubel FM, Calderwood SB
(2002) Virulence effect of Enterococcus faecalis protease genes and the quorum-sensing locus
fsr in Caenorhabditis elegans and mice. Infect Immun 70:5647–5650. https://doi.org/10.1128/
iai.70.10.5647-5650.2002
Singh VK, Kavita K, Prabhakaran R, Jha B (2013) Cis −9-octadecenoic acid from the rhizospheric
bacterium Stenotrophomonas maltophilia BJ01 shows quorum quenching and anti-biofilm
activities. Biofouling 29:855–867. https://doi.org/10.1080/08927014.2013.807914
Skandamis P, Nychas G-JE (2012) Quorum-sensing in the context of food microbiology downloaded from. Appl Environ Microbiol. https://doi.org/10.1128/AEM.00468-12
S. Kumar et al.
and a two-component regulatory system. Mol Microbiol 21:853–862. https://doi.
org/10.1046/j.1365-2958.1996.501417.x
Peters L, König GM, Wright AD, Pukall R, Stackebrandt E, Eberl L, Riedel K (2003) Secondary
metabolites of Flustra foliacea and their influence on bacteria. Appl Environ Microbiol
69:3469–3475. https://doi.org/10.1128/aem.69.6.3469-3475.2003
Pinkston KL, Gao P, Diaz-Garcia D, Sillanpää J, Nallapareddy SR, Murray BE, Harvey BR (2011)
The Fsr quorum-sensing system of Enterococcus faecalis modulates surface display of the
collagen-binding MSCRAMM ace through regulation of gelE. J Bacteriol 193:4317–4325.
https://doi.org/10.1128/JB.05026-11
Rajamani S, Bauer WD, Robinson JB, Farrow JM, Pesci EC, Teplitski M, Gao M, Sayre RT,
Phillips DA (2008) The vitamin riboflavin and its derivative Lumichrome activate the LasR
bacterial quorum-sensing receptor. Mol Plant-Microbe Interact 21:1184–1192. https://doi.
org/10.1094/MPMI-21-9-1184
Rajput A, Kaur K, Kumar M (2016) SigMol: repertoire of quorum-sensing signaling molecules in
prokaryotes. Nucleic Acids Res 44:D634–D639. https://doi.org/10.1093/nar/gkv1076
Rasmussen TB, Skindersoe ME, Bjarnsholt T, Phipps RK, Christensen KB, Jensen PO, Andersen
JB, Koch B, Larsen TO, Hentzer M, Eberl L, Hoiby N, Givskov M (2005) Identity and effects
of quorum-sensing inhibitors produced by Penicillium species. Microbiology 151:1325–1340.
https://doi.org/10.1099/mic.0.27715-0
Rémy B, Mion S, Plener L, Elias M, Chabrière E, Daudé D (2018) Interference in bacterial quorumsensing: a biopharmaceutical perspective. Front Pharmacol 9:203. https://doi.org/10.3389/
fphar.2018.00203
Rice SA, Givskov M, Høiby N, Parsek MR, Riedel K, Heydorn A, Eberl L, Andersen JB, Hentzer
M, Molin S, Kjelleberg S, Rasmussen TB (2002) Inhibition of quorum-sensing in Pseudomonas
aeruginosa biofilm bacteria by a halogenated furanone compound. Microbiology 148:87–102.
https://doi.org/10.1099/00221287-148-1-87
Rutherford ST, Bassler BL (2012) Bacterial quorum-sensing: its role in virulence and possibilities for its control. Cold Spring Harb Perspect Med 2:a012427. https://doi.org/10.1101/
CSHPERSPECT.A012427
Saiman L, Marshall BC, Mayer-Hamblett N, Burns JL, Quittner AL, Cibene DA, Coquillette S,
Fieberg AY, Accurso FJ, Campbell III PW, for the Macrolide Study Group (2003) Azithromycin
in patients with cystic fibrosis chronically infected with Pseudomonas aeruginosa. JAMA
290:1749. https://doi.org/10.1001/jama.290.13.1749
Seed PC, Passador L, Iglewski BH (1995) Activation of the Pseudomonas aeruginosa lasI gene by
LasR and the Pseudomonas autoinducer PAI: an autoinduction regulatory hierarchy. J Bacteriol
177:654–659. https://doi.org/10.1128/jb.177.3.654-659.1995
Shankar J, Walker RG, Ward D, Horsburgh MJ (2012) The enterococcus faecalis exoproteome:
identification and temporal regulation by fsr. PLoS One 7. https://doi.org/10.1371/journal.
pone.0033450
Shih P-C, Huang C-T (2002) Effects of quorum-sensing deficiency on Pseudomonas aeruginosa
biofilm formation and antibiotic resistance. J Antimicrob Chemother 49:309–314. https://doi.
org/10.1093/jac/49.2.309
Sifri CD, Mylonakis E, Singh KV, Qin X, Garsin DA, Murray BE, Ausubel FM, Calderwood SB
(2002) Virulence effect of Enterococcus faecalis protease genes and the quorum-sensing locus
fsr in Caenorhabditis elegans and mice. Infect Immun 70:5647–5650. https://doi.org/10.1128/
iai.70.10.5647-5650.2002
Singh VK, Kavita K, Prabhakaran R, Jha B (2013) Cis −9-octadecenoic acid from the rhizospheric
bacterium Stenotrophomonas maltophilia BJ01 shows quorum quenching and anti-biofilm
activities. Biofouling 29:855–867. https://doi.org/10.1080/08927014.2013.807914
Skandamis P, Nychas G-JE (2012) Quorum-sensing in the context of food microbiology downloaded from. Appl Environ Microbiol. https://doi.org/10.1128/AEM.00468-12
S. Kumar et al.