124
Gao W, Chua K, Davies JK, Newton HJ, Seemann T, Harrison PF, Holmes NE, Rhee HW,
Hong JI, Hartland EL, Stinear TP, Howden BP (2010) Two novel point mutations in clinical
Staphylococcus aureus reduce linezolid susceptibility and switch on the stringent response to
promote persistent infection. PLoS Pathog 6(6). https://doi.org/10.1371/journal.ppat.1000944
Germain E, Castro-Roa D, Zenkin N, Gerdes K (2013) Molecular mechanism of bacterial persistence by HipA. Mol Cell 52(2):248–254. https://doi.org/10.1016/j.molcel.2013.08.045
Glickman MS, Cox JS, Jacobs WR (2000) A novel mycolic acid cyclopropane synthetase is
required for cording, persistence, and virulence of Mycobacterium tuberculosis. Mol Cell
5(4):717–727. https://doi.org/10.1016/S1097-2765(00)80250-6
Goodman AL, Wu M, Gordon JI (2011) Identifying microbial fitness determinants by insertion
sequencing using genome-wide transposon mutant libraries. Nat Protoc 6(12):1969–1980.
https://doi.org/10.1038/nprot.2011.417
Gopinath V, Raghunandanan S, Gomez RL, Jose L, Surendran A, Ramachandran R, Pushparajan
AR, Mundayoor S, Jaleel A, Kumar RA (2015) Profiling the proteome of Mycobacterium
tuberculosis during dormancy and reactivation. Mol Cell Proteomics 14(8):2160–2176. https://
doi.org/10.1074/mcp.M115.051151
Gygi SP, Corthals GL, Zhang Y, Rochon Y, Aebersold R (2000) Evaluation of two-dimensional gel
electrophoresis-based proteome analysis technology. P Natl Acad Sci USA 97(17):9390–9395.
https://doi.org/10.1073/pnas.160270797
Harms A, Maisonneuve E, Gerdes K (2016) Mechanisms of bacterial persistence during stress and
antibiotic exposure. Science 354(6318). https://doi.org/10.1126/science.aaf4268
Haunreiter VD, Boumasmoud M, Häffner N, Wipfli D, Leimer N, Rachmühl C, Kühnert D,
Achermann Y, Zbinden R, Benussi S (2019) In-host evolution of Staphylococcus epidermidis in a pacemaker-associated endocarditis resulting in increased antibiotic tolerance. Nat
Commun 10(1):1149
Helaine S, Kugelberg E (2014) Bacterial persisters: formation, eradication, and experimental systems. Trends Microbiol 22(7):417–424. https://doi.org/10.1016/j.tim.2014.03.008
Helaine S, Thompson JA, Watson KG, Liu M, Boyle C, Holden DW (2010) Dynamics of intracellular bacterial replication at the single cell level. Proc Natl Acad Sci U S A 107(8):3746–3751.
https://doi.org/10.1073/pnas.1000041107
Helaine S, Cheverton AM, Watson KG, Faure LM, Matthews SA, Holden DW (2014)
Internalization of Salmonella by macrophages induces formation of nonreplicating persisters.
Science 343(6167):204–208. https://doi.org/10.1126/science.1244705
Henry TC, Brynildsen MP (2016) Development of persister-FACSeq: a method to massively
parallelize quantification of persister physiology and its heterogeneity. Sci Rep 6. https://doi.
org/10.1038/srep25100
Hobby GL, Meyer K, Chaffee E (1942) Observations on the mechanism of action of penicillin.
Exp Biol Med 50(2):281–285
Hu YM, Coates ARM (2005) Transposon mutagenesis identifies genes which control antimicrobial
drug tolerance in stationary-phase Escherichia coli. FEMS Microbiol Lett 243(1):117–124.
https://doi.org/10.1016/j.femsle.2004.11.049
Imamura H, Nhat KPH, Togawa H, Saito K, Iino R, Kato-Yamada Y, Nagai T, Noji H (2009)
Visualization of ATP levels inside single living cells with fluorescence resonance energy
transfer- based genetically encoded indicators. Proc Natl Acad Sci U S A 106(37):15651–15656.
https://doi.org/10.1073/pnas.0904764106
Jain P, Weinrick BC, Kalivoda EJ, Yang H, Munsamy V, Vilcheze C, Weisbrod TR, Larsen
MH, O’Donnell MR, Pym A, Jacobs WR (2016) Dual-reporter mycobacteriophages
(Phi(DRMs)-D-2) reveal preexisting Mycobacterium tuberculosis persistent cells in human
sputum. MBio 7(5). https://doi.org/10.1128/mBio.01023-16
Jõers A, Putrinš M, Kaldalu N, Luidalepp H, Tenson T (2019) Persister resuscitation persister cells
and infectious disease. Springer, pp 203–216
X. Duan et al.
Gao W, Chua K, Davies JK, Newton HJ, Seemann T, Harrison PF, Holmes NE, Rhee HW,
Hong JI, Hartland EL, Stinear TP, Howden BP (2010) Two novel point mutations in clinical
Staphylococcus aureus reduce linezolid susceptibility and switch on the stringent response to
promote persistent infection. PLoS Pathog 6(6). https://doi.org/10.1371/journal.ppat.1000944
Germain E, Castro-Roa D, Zenkin N, Gerdes K (2013) Molecular mechanism of bacterial persistence by HipA. Mol Cell 52(2):248–254. https://doi.org/10.1016/j.molcel.2013.08.045
Glickman MS, Cox JS, Jacobs WR (2000) A novel mycolic acid cyclopropane synthetase is
required for cording, persistence, and virulence of Mycobacterium tuberculosis. Mol Cell
5(4):717–727. https://doi.org/10.1016/S1097-2765(00)80250-6
Goodman AL, Wu M, Gordon JI (2011) Identifying microbial fitness determinants by insertion
sequencing using genome-wide transposon mutant libraries. Nat Protoc 6(12):1969–1980.
https://doi.org/10.1038/nprot.2011.417
Gopinath V, Raghunandanan S, Gomez RL, Jose L, Surendran A, Ramachandran R, Pushparajan
AR, Mundayoor S, Jaleel A, Kumar RA (2015) Profiling the proteome of Mycobacterium
tuberculosis during dormancy and reactivation. Mol Cell Proteomics 14(8):2160–2176. https://
doi.org/10.1074/mcp.M115.051151
Gygi SP, Corthals GL, Zhang Y, Rochon Y, Aebersold R (2000) Evaluation of two-dimensional gel
electrophoresis-based proteome analysis technology. P Natl Acad Sci USA 97(17):9390–9395.
https://doi.org/10.1073/pnas.160270797
Harms A, Maisonneuve E, Gerdes K (2016) Mechanisms of bacterial persistence during stress and
antibiotic exposure. Science 354(6318). https://doi.org/10.1126/science.aaf4268
Haunreiter VD, Boumasmoud M, Häffner N, Wipfli D, Leimer N, Rachmühl C, Kühnert D,
Achermann Y, Zbinden R, Benussi S (2019) In-host evolution of Staphylococcus epidermidis in a pacemaker-associated endocarditis resulting in increased antibiotic tolerance. Nat
Commun 10(1):1149
Helaine S, Kugelberg E (2014) Bacterial persisters: formation, eradication, and experimental systems. Trends Microbiol 22(7):417–424. https://doi.org/10.1016/j.tim.2014.03.008
Helaine S, Thompson JA, Watson KG, Liu M, Boyle C, Holden DW (2010) Dynamics of intracellular bacterial replication at the single cell level. Proc Natl Acad Sci U S A 107(8):3746–3751.
https://doi.org/10.1073/pnas.1000041107
Helaine S, Cheverton AM, Watson KG, Faure LM, Matthews SA, Holden DW (2014)
Internalization of Salmonella by macrophages induces formation of nonreplicating persisters.
Science 343(6167):204–208. https://doi.org/10.1126/science.1244705
Henry TC, Brynildsen MP (2016) Development of persister-FACSeq: a method to massively
parallelize quantification of persister physiology and its heterogeneity. Sci Rep 6. https://doi.
org/10.1038/srep25100
Hobby GL, Meyer K, Chaffee E (1942) Observations on the mechanism of action of penicillin.
Exp Biol Med 50(2):281–285
Hu YM, Coates ARM (2005) Transposon mutagenesis identifies genes which control antimicrobial
drug tolerance in stationary-phase Escherichia coli. FEMS Microbiol Lett 243(1):117–124.
https://doi.org/10.1016/j.femsle.2004.11.049
Imamura H, Nhat KPH, Togawa H, Saito K, Iino R, Kato-Yamada Y, Nagai T, Noji H (2009)
Visualization of ATP levels inside single living cells with fluorescence resonance energy
transfer- based genetically encoded indicators. Proc Natl Acad Sci U S A 106(37):15651–15656.
https://doi.org/10.1073/pnas.0904764106
Jain P, Weinrick BC, Kalivoda EJ, Yang H, Munsamy V, Vilcheze C, Weisbrod TR, Larsen
MH, O’Donnell MR, Pym A, Jacobs WR (2016) Dual-reporter mycobacteriophages
(Phi(DRMs)-D-2) reveal preexisting Mycobacterium tuberculosis persistent cells in human
sputum. MBio 7(5). https://doi.org/10.1128/mBio.01023-16
Jõers A, Putrinš M, Kaldalu N, Luidalepp H, Tenson T (2019) Persister resuscitation persister cells
and infectious disease. Springer, pp 203–216
X. Duan et al.