142
A. Ghasemnezhad et al.
Table 6.6 Some endophyte fungi as a medicinal source
Endophyte
Medicinal compound
References
Cylindrocarpon lucidum
Immunosuppressant
cyclosporine
Abdel-Azeem et al. (2019)
Tolypocladium inflatum
Immunosuppressant
cyclosporine
Abdel-Azeem et al. (2019)
Aspergillus terreus
Lovastatin
Abdel-Azeem et al. (2019)
Penicillium sp.
Antibiotic penicillin
Abdel-Azeem et al. (2019)
Chaetomium globosum
Anti-rheumatoid activity Abdel-Azeem et al. (2016)
Taxomyces andreanae
Taxol
Stierle et al. (1993)
Acremonium sp.
Paclitaxel (Taxol)
El-Bialy and El-Bastawisy
(2020)
Pestalotiopsis microspora
Paclitaxel (Taxol)
Kusari et al. (2014)
Fusarium solani
Camptothecin
(topoisomerase inhibitor)
Kusari et al. (2012)
Actinomycete
Actinosynnema pretiosum ssp.
auranticum
Maytansinoid
ansamitocin
Yu et al. (2002)
Diaporthe sp.
Diaporone A (new
dihydroisocoumarin),
α-dibenzopyrones
Guo et al. (2020)
Fusarium sp.
Huperzine A
Cruz-Miranda et al. (2020)
Ceriporia lacerata
Huperzine A
Zhang et al. (2015)
Trichoderma polyalthiae
Violaceol I and II
Nuankeaw et al. (2020)
B. amyloliquefaciens SB-9
Melatonin
Jiao et al. (2016)
Streptomyces Strain MS-6-6
Treponemycin
(Anti-tuberculous)
Mahmoud et al. (2015)
Streptomyces sp. MK932-CF8
Androprostamines
(Anti-prostate cancer)
Yamazaki et al. (2015)
Pseudomonas syringae
Pseudomycin
McEvoy et al. (2016)
emodin, deoxypodophyllotoxin, antineoplastic camptothecin (CPT), as well as the
natural insecticides azadirachtin A and B (Table 6.6).
6.11 Endophytes in Agriculture and Medicine: Future
Prospects
Since the emergence of mankind, plants have always been a major nutritional source,
along with animals, for us so that they have been used as a source of food and
treatment. Today, given the industrial development and population growth in most
countries, land fragmentation into small parcels has reduced farmlands and crop
A. Ghasemnezhad et al.
Table 6.6 Some endophyte fungi as a medicinal source
Endophyte
Medicinal compound
References
Cylindrocarpon lucidum
Immunosuppressant
cyclosporine
Abdel-Azeem et al. (2019)
Tolypocladium inflatum
Immunosuppressant
cyclosporine
Abdel-Azeem et al. (2019)
Aspergillus terreus
Lovastatin
Abdel-Azeem et al. (2019)
Penicillium sp.
Antibiotic penicillin
Abdel-Azeem et al. (2019)
Chaetomium globosum
Anti-rheumatoid activity Abdel-Azeem et al. (2016)
Taxomyces andreanae
Taxol
Stierle et al. (1993)
Acremonium sp.
Paclitaxel (Taxol)
El-Bialy and El-Bastawisy
(2020)
Pestalotiopsis microspora
Paclitaxel (Taxol)
Kusari et al. (2014)
Fusarium solani
Camptothecin
(topoisomerase inhibitor)
Kusari et al. (2012)
Actinomycete
Actinosynnema pretiosum ssp.
auranticum
Maytansinoid
ansamitocin
Yu et al. (2002)
Diaporthe sp.
Diaporone A (new
dihydroisocoumarin),
α-dibenzopyrones
Guo et al. (2020)
Fusarium sp.
Huperzine A
Cruz-Miranda et al. (2020)
Ceriporia lacerata
Huperzine A
Zhang et al. (2015)
Trichoderma polyalthiae
Violaceol I and II
Nuankeaw et al. (2020)
B. amyloliquefaciens SB-9
Melatonin
Jiao et al. (2016)
Streptomyces Strain MS-6-6
Treponemycin
(Anti-tuberculous)
Mahmoud et al. (2015)
Streptomyces sp. MK932-CF8
Androprostamines
(Anti-prostate cancer)
Yamazaki et al. (2015)
Pseudomonas syringae
Pseudomycin
McEvoy et al. (2016)
emodin, deoxypodophyllotoxin, antineoplastic camptothecin (CPT), as well as the
natural insecticides azadirachtin A and B (Table 6.6).
6.11 Endophytes in Agriculture and Medicine: Future
Prospects
Since the emergence of mankind, plants have always been a major nutritional source,
along with animals, for us so that they have been used as a source of food and
treatment. Today, given the industrial development and population growth in most
countries, land fragmentation into small parcels has reduced farmlands and crop