13 Viral PDZ Binding Motifs Influence Cell Behavior Through
the Interaction with Cellular Proteins Containing PDZ Domains . . . . . . . . . . . . . 217
Carlos Castan ˜o-Rodriguez, Jose M. Honrubia,
Javier Gutie ´rrez-A ´ lvarez, Isabel Sola, and Luis Enjuanes
14 Computational Design of PDZ-Peptide Binding. . . . . . . . . . . . . . . . . . . . . . . . . . . . 237
Nicolas Panel, Francesco Villa, Vaitea Opuu, David Mignon,
and Thomas Simonson
15 Mechanoregulation of PDZ Proteins, An Emerging Function . . . . . . . . . . . . . . . . 257
Elsa Bazellie `res and Andre ´ Le Bivic
16 Rational Design of PDZ Domain Inhibitors: Discovery
of Small Organic Compounds Targeting PDZ Domains . . . . . . . . . . . . . . . . . . . . . 277
Laurent Hoffer, Philippe Roche, and Xavier Morelli
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 291
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