cell envelope permeability and antibiotic resistance of mycobacterium abscessus. Front
Microbiol 8:2123. https://doi.org/10.3389/
fmicb.2017.02123
14. Laneelle MA, Nigou J, Daffe M (2015) Lipid
and lipoarabinomannan isolation and characterization. Methods Mol Biol 1285:77–103.
https://doi.org/10.1007/978-1-4939-24509_5
15. Parra J, Marcoux J, Poncin I, Canaan S, Herrmann JL, Nigou J, Burlet-Schiltz O, Riviere M
(2017) Scrutiny of Mycobacterium tuberculosis
19 kDa antigen proteoforms provides new
insights in the lipoglycoprotein biogenesis paradigm. Sci Rep 7:43682. https://doi.org/10.
1038/srep43682
16. Nigou J, Gilleron M, Brando T, Puzo G
(2004) Structural analysis of mycobacterial
lipoglycans. Appl Biochem Biotechnol 118
(1–3):253–267.
https://doi.org/10.1385/
abab:118:1-3:253
17. Slayden RA, Barry CE 3rd (2001) Analysis of
the lipids of Mycobacterium tuberculosis. Methods Mol Med 54:229–245. https://doi.org/
10.1385/1-59259-147-7:229
18. Lane ´elle M, Nigou J, Daffe ´ M (2005) Lipid
and Lipoarabinomannan isolation and characterization. In: T. P, D. R (eds) Mycobacteria
protocols, vol 1285. Humana Press, New York,
NY.
doi:https://doi.org/10.1007/978-14939-2450-9_5
19. Portevin D, Sukumar S, Coscolla M, Shui G,
Li B, Guan XL, Bendt AK, Young D,
Gagneux S, Wenk MR (2014) Lipidomics and
genomics of Mycobacterium tuberculosis
reveal lineage-specific trends in mycolic acid
biosynthesis.
MicrobiologyOpen
3
(6):823–835.
https://doi.org/10.1002/
mbo3.193
20. Shui G, Bendt AK, Jappar IA, Lim HM,
Laneelle M, Herve M, Via LE, Chua GH,
Bratschi MW, Zainul Rahim SZ, Michelle AL,
Hwang SH, Lee JS, Eum SY, Kwak HK,
Daffe M, Dartois V, Michel G, Barry CE 3rd,
Wenk MR (2012) Mycolic acids as diagnostic
markers for tuberculosis case detection in
humans and drug efficacy in mice. EMBO
Mol Med 4(1):27–37. https://doi.org/10.
1002/emmm.201100185
21. Layre E, Paepe DC, Larrouy-Maumus G,
Vaubourgeix J, Mundayoor S, Lindner B,
Puzo G, Gilleron M (2011) Deciphering sulfoglycolipids of Mycobacterium tuberculosis. J
Lipid Res 52(6):1098–1110. https://doi.org/
10.1194/jlr.M013482
22. Jain M, Petzold CJ, Schelle MW, Leavell MD,
Mougous JD, Bertozzi CR, Leary JA, Cox JS
(2007) Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling. Proc Natl Acad Sci U S A 104
(12):5133–5138. https://doi.org/10.1073/
pnas.0610634104
23. Larrouy-Maumus G, Puzo G (2015) Mycobacterial envelope lipids fingerprint from direct
MALDI-TOF MS analysis of intact bacilli.
Tuberculosis 95(1):75–85. https://doi.org/
10.1016/j.tube.2014.11.001
24. Gilleron M, Lindner B, Puzo G (2006)
MS/MS approach for characterization of the
fatty acid distribution on mycobacterial
phosphatidyl-myo-inositol mannosides. Anal
Chem 78(24):8543–8548. https://doi.org/
10.1021/ac061574a
25. Hsu FF, Turk J, Owens RM, Rhoades ER,
Russell DG (2007) Structural characterization
of phosphatidyl-myo-inositol mannosides from
Mycobacterium bovis bacillus Calmette Guerin
by multiple-stage quadrupole ion-trap mass
spectrometry
with
electrospray
ionization. I. PIMs and lyso-PIMs. J Am Soc
Mass Spectrom 18(3):466–478. https://doi.
org/10.1016/j.jasms.2006.10.012
26. Hsu FF, Turk J, Owens RM, Rhoades ER,
Russell DG (2007) Structural characterization
of phosphatidyl-myo-inositol mannosides from
Mycobacterium bovis bacillus Calmette Guerin
by multiple-stage quadrupole ion-trap mass
spectrometry with electrospray ionization.
II. Monoacyl- and diacyl-PIMs. J Am Soc
Mass Spectrom 18(3):479–492. https://doi.
org/10.1016/j.jasms.2006.10.020
27. Fujita Y, Naka T, Doi T, Yano I (2005) Direct
molecular mass determination of trehalose
monomycolate from 11 species of mycobacteria by MALDI-TOF mass spectrometry.
Microbiology 151(Pt 5):1443–1452. https://
doi.org/10.1099/mic.0.27791-0
28. Fujita Y, Naka T, McNeil MR, Yano I (2005)
Intact molecular characterization of cord factor
(trehalose 6,6
0 -dimycolate) from nine species
of mycobacteria by MALDI-TOF mass spectrometry.
Microbiology
151
(Pt 10):3403–3416. https://doi.org/10.
1099/mic.0.28158-0
29. Madigan CA, Cheng TY, Layre E, Young DC,
McConnell MJ, Debono CA, Murry JP, Wei
JR, Barry CE 3rd, Rodriguez GM,
Matsunaga I, Rubin EJ, Moody DB (2012)
Lipidomic discovery of deoxysiderophores
reveals a revised mycobactin biosynthesis pathway in Mycobacterium tuberculosis. Proc Natl
Acad Sci U S A 109(4):1257–1262. https://
doi.org/10.1073/pnas.1109958109
576
Emilie Layre
Microbiol 8:2123. https://doi.org/10.3389/
fmicb.2017.02123
14. Laneelle MA, Nigou J, Daffe M (2015) Lipid
and lipoarabinomannan isolation and characterization. Methods Mol Biol 1285:77–103.
https://doi.org/10.1007/978-1-4939-24509_5
15. Parra J, Marcoux J, Poncin I, Canaan S, Herrmann JL, Nigou J, Burlet-Schiltz O, Riviere M
(2017) Scrutiny of Mycobacterium tuberculosis
19 kDa antigen proteoforms provides new
insights in the lipoglycoprotein biogenesis paradigm. Sci Rep 7:43682. https://doi.org/10.
1038/srep43682
16. Nigou J, Gilleron M, Brando T, Puzo G
(2004) Structural analysis of mycobacterial
lipoglycans. Appl Biochem Biotechnol 118
(1–3):253–267.
https://doi.org/10.1385/
abab:118:1-3:253
17. Slayden RA, Barry CE 3rd (2001) Analysis of
the lipids of Mycobacterium tuberculosis. Methods Mol Med 54:229–245. https://doi.org/
10.1385/1-59259-147-7:229
18. Lane ´elle M, Nigou J, Daffe ´ M (2005) Lipid
and Lipoarabinomannan isolation and characterization. In: T. P, D. R (eds) Mycobacteria
protocols, vol 1285. Humana Press, New York,
NY.
doi:https://doi.org/10.1007/978-14939-2450-9_5
19. Portevin D, Sukumar S, Coscolla M, Shui G,
Li B, Guan XL, Bendt AK, Young D,
Gagneux S, Wenk MR (2014) Lipidomics and
genomics of Mycobacterium tuberculosis
reveal lineage-specific trends in mycolic acid
biosynthesis.
MicrobiologyOpen
3
(6):823–835.
https://doi.org/10.1002/
mbo3.193
20. Shui G, Bendt AK, Jappar IA, Lim HM,
Laneelle M, Herve M, Via LE, Chua GH,
Bratschi MW, Zainul Rahim SZ, Michelle AL,
Hwang SH, Lee JS, Eum SY, Kwak HK,
Daffe M, Dartois V, Michel G, Barry CE 3rd,
Wenk MR (2012) Mycolic acids as diagnostic
markers for tuberculosis case detection in
humans and drug efficacy in mice. EMBO
Mol Med 4(1):27–37. https://doi.org/10.
1002/emmm.201100185
21. Layre E, Paepe DC, Larrouy-Maumus G,
Vaubourgeix J, Mundayoor S, Lindner B,
Puzo G, Gilleron M (2011) Deciphering sulfoglycolipids of Mycobacterium tuberculosis. J
Lipid Res 52(6):1098–1110. https://doi.org/
10.1194/jlr.M013482
22. Jain M, Petzold CJ, Schelle MW, Leavell MD,
Mougous JD, Bertozzi CR, Leary JA, Cox JS
(2007) Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling. Proc Natl Acad Sci U S A 104
(12):5133–5138. https://doi.org/10.1073/
pnas.0610634104
23. Larrouy-Maumus G, Puzo G (2015) Mycobacterial envelope lipids fingerprint from direct
MALDI-TOF MS analysis of intact bacilli.
Tuberculosis 95(1):75–85. https://doi.org/
10.1016/j.tube.2014.11.001
24. Gilleron M, Lindner B, Puzo G (2006)
MS/MS approach for characterization of the
fatty acid distribution on mycobacterial
phosphatidyl-myo-inositol mannosides. Anal
Chem 78(24):8543–8548. https://doi.org/
10.1021/ac061574a
25. Hsu FF, Turk J, Owens RM, Rhoades ER,
Russell DG (2007) Structural characterization
of phosphatidyl-myo-inositol mannosides from
Mycobacterium bovis bacillus Calmette Guerin
by multiple-stage quadrupole ion-trap mass
spectrometry
with
electrospray
ionization. I. PIMs and lyso-PIMs. J Am Soc
Mass Spectrom 18(3):466–478. https://doi.
org/10.1016/j.jasms.2006.10.012
26. Hsu FF, Turk J, Owens RM, Rhoades ER,
Russell DG (2007) Structural characterization
of phosphatidyl-myo-inositol mannosides from
Mycobacterium bovis bacillus Calmette Guerin
by multiple-stage quadrupole ion-trap mass
spectrometry with electrospray ionization.
II. Monoacyl- and diacyl-PIMs. J Am Soc
Mass Spectrom 18(3):479–492. https://doi.
org/10.1016/j.jasms.2006.10.020
27. Fujita Y, Naka T, Doi T, Yano I (2005) Direct
molecular mass determination of trehalose
monomycolate from 11 species of mycobacteria by MALDI-TOF mass spectrometry.
Microbiology 151(Pt 5):1443–1452. https://
doi.org/10.1099/mic.0.27791-0
28. Fujita Y, Naka T, McNeil MR, Yano I (2005)
Intact molecular characterization of cord factor
(trehalose 6,6
0 -dimycolate) from nine species
of mycobacteria by MALDI-TOF mass spectrometry.
Microbiology
151
(Pt 10):3403–3416. https://doi.org/10.
1099/mic.0.28158-0
29. Madigan CA, Cheng TY, Layre E, Young DC,
McConnell MJ, Debono CA, Murry JP, Wei
JR, Barry CE 3rd, Rodriguez GM,
Matsunaga I, Rubin EJ, Moody DB (2012)
Lipidomic discovery of deoxysiderophores
reveals a revised mycobactin biosynthesis pathway in Mycobacterium tuberculosis. Proc Natl
Acad Sci U S A 109(4):1257–1262. https://
doi.org/10.1073/pnas.1109958109
576
Emilie Layre