3
Large-Scale Production of BNC:
State and Challenges
Dana Kralisch and Nadine Hessler
Friedrich Schiller University, Institute of Technical Chemistry and
Environmental Chemistry, Jena, Germany
CONTENTS
Introduction............................................................................................................44
Agitated.Forms.of.Cultivation............................................................................. 48
Introduction....................................................................................................... 48
Benefits.and.Limits.of.Agitated.Cultivation.Forms..................................... 48
Reactor.Types..................................................................................................... 50
Agitated.Cultivation.by.Shaking.................................................................... 51
Agitated.Cultivation.by.Stirring..................................................................... 52
Batch.Fermentation.under.Stirring.Using.Plastic.Composite.Supports. ... 53
Airlift.Reactors. ..................................................................................................54
Static.Cultivation. ................................................................................................... 57
Introduction....................................................................................................... 57
Benefits.and.Limitations.of.Static.Cultivation.Forms.in.Batch.Vessels..... 58
Fed-Batch.Cultivation. ...................................................................................... 58
Combination.of.Static.and.Moving.Cultivation................................................ 60
Static.Cultivation.with.Moving.Harvesting.................................................. 60
Non-Static-Film.Bioreactors. ............................................................................ 61
(Semi)continuous.Generation.of.Flat.BNC....................................................63
Conclusions. ............................................................................................................65
References. ...............................................................................................................65
This.chapter.provides.an.overview.of.the.methods.and.reactor.devices.
used. for. the. generation. of. bacterial. nanocellulose. (BNC).. Cultivation.
approaches. ranging. from. batch,. to. fed-batch,. to. continuous. operation.
under. agitated,. static,. and. nonstatic. conditions. are. described. in. detail.
and.the.advantages.as.well.as.the.limitations.of.these.methods.are.discussed..Typically.utilized.types.of.reactors.are.introduced.and.reviewed.
against.the.current.state.of.BNC.generation.within.these.devices.
43
Large-Scale Production of BNC:
State and Challenges
Dana Kralisch and Nadine Hessler
Friedrich Schiller University, Institute of Technical Chemistry and
Environmental Chemistry, Jena, Germany
CONTENTS
Introduction............................................................................................................44
Agitated.Forms.of.Cultivation............................................................................. 48
Introduction....................................................................................................... 48
Benefits.and.Limits.of.Agitated.Cultivation.Forms..................................... 48
Reactor.Types..................................................................................................... 50
Agitated.Cultivation.by.Shaking.................................................................... 51
Agitated.Cultivation.by.Stirring..................................................................... 52
Batch.Fermentation.under.Stirring.Using.Plastic.Composite.Supports. ... 53
Airlift.Reactors. ..................................................................................................54
Static.Cultivation. ................................................................................................... 57
Introduction....................................................................................................... 57
Benefits.and.Limitations.of.Static.Cultivation.Forms.in.Batch.Vessels..... 58
Fed-Batch.Cultivation. ...................................................................................... 58
Combination.of.Static.and.Moving.Cultivation................................................ 60
Static.Cultivation.with.Moving.Harvesting.................................................. 60
Non-Static-Film.Bioreactors. ............................................................................ 61
(Semi)continuous.Generation.of.Flat.BNC....................................................63
Conclusions. ............................................................................................................65
References. ...............................................................................................................65
This.chapter.provides.an.overview.of.the.methods.and.reactor.devices.
used. for. the. generation. of. bacterial. nanocellulose. (BNC).. Cultivation.
approaches. ranging. from. batch,. to. fed-batch,. to. continuous. operation.
under. agitated,. static,. and. nonstatic. conditions. are. described. in. detail.
and.the.advantages.as.well.as.the.limitations.of.these.methods.are.discussed..Typically.utilized.types.of.reactors.are.introduced.and.reviewed.
against.the.current.state.of.BNC.generation.within.these.devices.
43