15
Biosynthesis of Bacterial Cellulose
with.unique.properties..Modification.of.cellulose.synthesis.in.G. xylinus.by.
genetic.manipulations.has.not.been.very.successful,.and.thus.identification.
of.new.bacterial.species.with.the.ability.to.produce.significant.quantities.of.
cellulose.with.novel.and.desirable.properties.may.allow.for.a.much.wider.
range.of.applications.of.BNC.
Acknowledgment
Supported.in.part.by.Welch.Grant.F1217.to.R..Malcolm.Brown,.Jr.
References
Aloni,.Y.,.D..P..Delmer,.and.M..Benziman..1982..Achievement.of.high.rates.of.in.vitro.
synthesis.of.1,4-β-glucan:.activation.by.cooperative.interaction.of.the.Acetobacter
xylinum. enzyme. system. with. GTP,. polyethylene. glycol,. and. a. protein. factor..
Proc. Natl. Acad. Sci. USA.79:6448–6452.
Amikam,.D.,.and.M..Y..Galperin..2006..PilZ.domain.is.part.of.the.bacterial.c-di-GMP.
binding.protein..Bioinformatics.22:3–6.
Benziman,.M.,.C..H..Haigler,.R..M..Brown,.Jr.,.A..R..White,.and.K..M..Cooper..1980..
Cellulose.biogenesis:.polymerization.and.crystallization.are.coupled.processes.
in.Acetobacter xylinum..Proc. Natl. Acad. Sci. USA.77:6678–6682.
Brown,. R.. M.,. Jr... 1996.. The. biosynthesis. of. cellulose.. J. Macromol. Sci. – Pure Appl.
Chem..A33:1345–1373.
Brown,.R..M.,.Jr.,.and.D..Montezinos..1976..Cellulose.microfibrils:.visualization.of.biosynthetic.and.orienting.complexes.in.association.with.the.plasma.membrane..
Proc. Natl. Acad. Sci. USA.73:143–147.
Brown,.R..M.,.Jr.,.J..H..M..Willison,.and.C..L..Richardson..1976..Cellulose.biosynthesis.
in.Acetobacter xylinum:.visualization.of.the.site.of.synthesis.and.direct.measurement.of.the.in.vivo.process..Proc. Natl. Acad. Sci. USA.73:4565–4569.
Bureau,.T..E.,.and.R..M..Brown,.Jr..1987..In.vitro.synthesis.of.cellulose.II.from.a.cytoplasmic.
membrane.fraction.of.Acetobacter xylinum..Proc. Natl. Acad. Sci. USA.84:6985–6989.
Chen,. H.. P.,. and. R.. M.. Brown,. Jr.. 1996.. Immunochemical. studies. of. the. cellulose.
. synthase.complex.in.Acetobacter xylinum..Cellulose.3:63–75.
Cousins,.S..K.,.and.R..M..Brown,.Jr..1995..Cellulose.I.microfibril.assembly:.computational.molecular.mechanics.energy.analysis.favors.bonding.by.van.der.Waals.
forces.as.the.initial.step.in.crystallization..Polymer.36:3885–3888.
Cousins,. S.. K.,. and. R.. M.. Brown,. Jr.. 1997a.. Photoisomerization. of. a. dye-altered.
β-1,4-glucan.sheet.induces.the.crystallization.of.a.cellulose.composite..Polymer.
38:903–912.
Biosynthesis of Bacterial Cellulose
with.unique.properties..Modification.of.cellulose.synthesis.in.G. xylinus.by.
genetic.manipulations.has.not.been.very.successful,.and.thus.identification.
of.new.bacterial.species.with.the.ability.to.produce.significant.quantities.of.
cellulose.with.novel.and.desirable.properties.may.allow.for.a.much.wider.
range.of.applications.of.BNC.
Acknowledgment
Supported.in.part.by.Welch.Grant.F1217.to.R..Malcolm.Brown,.Jr.
References
Aloni,.Y.,.D..P..Delmer,.and.M..Benziman..1982..Achievement.of.high.rates.of.in.vitro.
synthesis.of.1,4-β-glucan:.activation.by.cooperative.interaction.of.the.Acetobacter
xylinum. enzyme. system. with. GTP,. polyethylene. glycol,. and. a. protein. factor..
Proc. Natl. Acad. Sci. USA.79:6448–6452.
Amikam,.D.,.and.M..Y..Galperin..2006..PilZ.domain.is.part.of.the.bacterial.c-di-GMP.
binding.protein..Bioinformatics.22:3–6.
Benziman,.M.,.C..H..Haigler,.R..M..Brown,.Jr.,.A..R..White,.and.K..M..Cooper..1980..
Cellulose.biogenesis:.polymerization.and.crystallization.are.coupled.processes.
in.Acetobacter xylinum..Proc. Natl. Acad. Sci. USA.77:6678–6682.
Brown,. R.. M.,. Jr... 1996.. The. biosynthesis. of. cellulose.. J. Macromol. Sci. – Pure Appl.
Chem..A33:1345–1373.
Brown,.R..M.,.Jr.,.and.D..Montezinos..1976..Cellulose.microfibrils:.visualization.of.biosynthetic.and.orienting.complexes.in.association.with.the.plasma.membrane..
Proc. Natl. Acad. Sci. USA.73:143–147.
Brown,.R..M.,.Jr.,.J..H..M..Willison,.and.C..L..Richardson..1976..Cellulose.biosynthesis.
in.Acetobacter xylinum:.visualization.of.the.site.of.synthesis.and.direct.measurement.of.the.in.vivo.process..Proc. Natl. Acad. Sci. USA.73:4565–4569.
Bureau,.T..E.,.and.R..M..Brown,.Jr..1987..In.vitro.synthesis.of.cellulose.II.from.a.cytoplasmic.
membrane.fraction.of.Acetobacter xylinum..Proc. Natl. Acad. Sci. USA.84:6985–6989.
Chen,. H.. P.,. and. R.. M.. Brown,. Jr.. 1996.. Immunochemical. studies. of. the. cellulose.
. synthase.complex.in.Acetobacter xylinum..Cellulose.3:63–75.
Cousins,.S..K.,.and.R..M..Brown,.Jr..1995..Cellulose.I.microfibril.assembly:.computational.molecular.mechanics.energy.analysis.favors.bonding.by.van.der.Waals.
forces.as.the.initial.step.in.crystallization..Polymer.36:3885–3888.
Cousins,. S.. K.,. and. R.. M.. Brown,. Jr.. 1997a.. Photoisomerization. of. a. dye-altered.
β-1,4-glucan.sheet.induces.the.crystallization.of.a.cellulose.composite..Polymer.
38:903–912.