Figure 11.6
234
Bacterial Cellulose
Deposited CaP Mineral (w/w%)
BC
BCTEMPO
BCTEMPOCa
M1604 1604A
M0020 1604B
M0020 1010B
M0020 0416B
0
20
40
60
80
0
1
2
3
4
5
6
Soaking Cycle
Figure 11.6
Relative.weight.of.Ca-P.mineral.deposit.on.different.BC.templates.as.a.function.of.the.number.
of.soaking.cycles..Source:.From.Nge.et.al.,.Biopolymers.(ISBN:978-953-307-109-1,.InTech.,.2010),.
345–368,.with.permission.
soaking.cycle.was.very.low..After.a.gradual.increase.of.the.mineral.deposition.during.the.first.three.cycles,.the.deposition.became.fairly.stable.between.
the.third.and.fourth.cycles.in.all.BC-GlcNAc.templates..The.entire.BC.surface.
was.covered.with.a.Ca-P.mineral.at.this.stage,.which.was.in.agreement.with.
the.observation.of.the.formation.of.Ca-P.layers.in.the.FE-SEM.images..The.
increase.of.Ca-P.deposition.between.the.fourth.and.fifth.cycles.reflects.the.
further.growth.of.apatite.globules.visible.in.the.FE-SEM.images.(Figure 11.5).
The.surface.of.the.BC.microfibril.network.may.be.considered.a.matrix.of.
chemical. groups.. Therefore. every. monomer. unit. at. the. surface. is. a. potential.nucleation.site.for.interaction.with.calcium.and/or.phosphate.ions..The.
accessibility. of. these. units. at. the. surface. to. the. ions. in. 1.5. SBF. or. calcium.
and.phosphate.solutions.depends.on.the.orientation.of.the.polymer.chains.
. making. up. the. matrix. as. well. as. the. pore. size. and. the. pore. distribution.
within.the.network..Subtle.morphological.changes.at.the.surfaces.of.various.
BC. templates. during. apatite. formation. as. well. as. varying. weight. deposits.
and.Ca:P.ratios.are.observed.accordingly.
Conclusion
Various.biodegradable.and.biocompatible.polymeric.materials.have.recently.
been. investigated. to. fabricate. inorganic–organic. hybrid. composites. by.
234
Bacterial Cellulose
Deposited CaP Mineral (w/w%)
BC
BCTEMPO
BCTEMPOCa
M1604 1604A
M0020 1604B
M0020 1010B
M0020 0416B
0
20
40
60
80
0
1
2
3
4
5
6
Soaking Cycle
Figure 11.6
Relative.weight.of.Ca-P.mineral.deposit.on.different.BC.templates.as.a.function.of.the.number.
of.soaking.cycles..Source:.From.Nge.et.al.,.Biopolymers.(ISBN:978-953-307-109-1,.InTech.,.2010),.
345–368,.with.permission.
soaking.cycle.was.very.low..After.a.gradual.increase.of.the.mineral.deposition.during.the.first.three.cycles,.the.deposition.became.fairly.stable.between.
the.third.and.fourth.cycles.in.all.BC-GlcNAc.templates..The.entire.BC.surface.
was.covered.with.a.Ca-P.mineral.at.this.stage,.which.was.in.agreement.with.
the.observation.of.the.formation.of.Ca-P.layers.in.the.FE-SEM.images..The.
increase.of.Ca-P.deposition.between.the.fourth.and.fifth.cycles.reflects.the.
further.growth.of.apatite.globules.visible.in.the.FE-SEM.images.(Figure 11.5).
The.surface.of.the.BC.microfibril.network.may.be.considered.a.matrix.of.
chemical. groups.. Therefore. every. monomer. unit. at. the. surface. is. a. potential.nucleation.site.for.interaction.with.calcium.and/or.phosphate.ions..The.
accessibility. of. these. units. at. the. surface. to. the. ions. in. 1.5. SBF. or. calcium.
and.phosphate.solutions.depends.on.the.orientation.of.the.polymer.chains.
. making. up. the. matrix. as. well. as. the. pore. size. and. the. pore. distribution.
within.the.network..Subtle.morphological.changes.at.the.surfaces.of.various.
BC. templates. during. apatite. formation. as. well. as. varying. weight. deposits.
and.Ca:P.ratios.are.observed.accordingly.
Conclusion
Various.biodegradable.and.biocompatible.polymeric.materials.have.recently.
been. investigated. to. fabricate. inorganic–organic. hybrid. composites. by.