8
Wound Dressings and Cosmetic Materials
from Bacterial Nanocellulose
Stanislaw Bielecki, Halina Kalinowska, Alina Krystynowicz,
Katarzyna Kubiak, Marek Kołodziejczyk, and Manu de Groeve
Institute of Technical Biochemistry, Technical University of Lodz, Lodz, Poland
CONTENTS
Performance.Requirements.of.Wound.Dressings........................................... 158
Properties.of.BNC.Dressings.............................................................................. 160
BNC.Dressings.with.Antimicrobial.Properties........................................... 164
BNC.Dressings.with.Antioxidant.and.Protease-Binding.Activities. ........ 166
Bioresorbable.BNC.Wound.Dressings. ......................................................... 167
Nanocomposite.BNC.Dressings. ................................................................... 167
Other.BNC.Dressings. ..................................................................................... 168
Applications.of.BNC.Dressings......................................................................... 168
Burns................................................................................................................. 168
Hernia............................................................................................................... 169
Venous.Leg.Ulcers. .......................................................................................... 170
Skin.Tears. ......................................................................................................... 170
Cosmetic.Applications.of.Bacterial.Cellulose.................................................. 170
Closing.Remarks.................................................................................................. 172
References. ............................................................................................................. 172
Bacterial. nanocellulose. (BNC). has. proven. to. be. a. versatile. biomaterial.
that. can. be. used. to. fabricate. excellent. wound. dressings. that. promote.
rapid. and. virtually. painless. wound. healing. as. well. as. cosmetics. with.
moisturizing. and. antiaging. activities.. It. is. a. natural,. nontoxic,. and.
stable. hydrogel. with. excellent. affinity. to. connective. tissue.. Properties.
of. microbial. nanocellulose. are. the. same. as. those. of. ideal. wound. care.
dressings:.(1).it.is.biocompatible.and.causes.neither.toxic.nor.allergic.side.
effects. when. remaining. in. long-term. contact. with. living. tissues;. (b). it.
displays.high.water-holding.capacity.(up.to.100.times.its.dry.mass).and.
maintains.a.moist.environment.at.the.wound.surface,.which.in.turn.prevents. additional. tissue. loss. from. dehydration,. stimulates. the. action. of.
lytic.enzymes.that.remove.residual.debris.in.the.early.stages.of.wound.
157
Wound Dressings and Cosmetic Materials
from Bacterial Nanocellulose
Stanislaw Bielecki, Halina Kalinowska, Alina Krystynowicz,
Katarzyna Kubiak, Marek Kołodziejczyk, and Manu de Groeve
Institute of Technical Biochemistry, Technical University of Lodz, Lodz, Poland
CONTENTS
Performance.Requirements.of.Wound.Dressings........................................... 158
Properties.of.BNC.Dressings.............................................................................. 160
BNC.Dressings.with.Antimicrobial.Properties........................................... 164
BNC.Dressings.with.Antioxidant.and.Protease-Binding.Activities. ........ 166
Bioresorbable.BNC.Wound.Dressings. ......................................................... 167
Nanocomposite.BNC.Dressings. ................................................................... 167
Other.BNC.Dressings. ..................................................................................... 168
Applications.of.BNC.Dressings......................................................................... 168
Burns................................................................................................................. 168
Hernia............................................................................................................... 169
Venous.Leg.Ulcers. .......................................................................................... 170
Skin.Tears. ......................................................................................................... 170
Cosmetic.Applications.of.Bacterial.Cellulose.................................................. 170
Closing.Remarks.................................................................................................. 172
References. ............................................................................................................. 172
Bacterial. nanocellulose. (BNC). has. proven. to. be. a. versatile. biomaterial.
that. can. be. used. to. fabricate. excellent. wound. dressings. that. promote.
rapid. and. virtually. painless. wound. healing. as. well. as. cosmetics. with.
moisturizing. and. antiaging. activities.. It. is. a. natural,. nontoxic,. and.
stable. hydrogel. with. excellent. affinity. to. connective. tissue.. Properties.
of. microbial. nanocellulose. are. the. same. as. those. of. ideal. wound. care.
dressings:.(1).it.is.biocompatible.and.causes.neither.toxic.nor.allergic.side.
effects. when. remaining. in. long-term. contact. with. living. tissues;. (b). it.
displays.high.water-holding.capacity.(up.to.100.times.its.dry.mass).and.
maintains.a.moist.environment.at.the.wound.surface,.which.in.turn.prevents. additional. tissue. loss. from. dehydration,. stimulates. the. action. of.
lytic.enzymes.that.remove.residual.debris.in.the.early.stages.of.wound.
157