5
Bacterial Cellulose Surface Modifications
João P. Silva, Fábia K. Andrade, and Francisco Miguel Gama
Center of Biological Engineering, Institute for Biotechnology and
Bioengineering, University of Minho, Braga, Portugal
CONTENTS
Cell.Adhesion......................................................................................................... 91
Biodegradation....................................................................................................... 97
Incorporation.of.Antimicrobial.Agents. ............................................................ 100
Enzyme.Immobilization. ..................................................................................... 101
Immobilization.of.Cells....................................................................................... 103
Modifications.for.Optoelectronic.Devices........................................................ 104
Hydrophobic.Derivatives................................................................................... 105
Precipitation.of.Metal.Ions. ................................................................................. 106
Acknowledgment. ................................................................................................ 107
References. ............................................................................................................. 108
The.unique.properties.of.bacterial.nanocellulose.(BNC).provide.the.basis.
for.a.wide.range.of.applications.in.human.and.veterinary.medicine,.odontology,.pharmaceuticals,.acoustic.and.filter.membranes,.biotechnological.
devices,.and.in.the.food.and.paper.industry..In.this.chapter,.an.overview.
of. surface. modifications. of. bacterial. cellulose.is.presented..Depending.
on.the.envisaged.applications,.chemical.modifications,.incorporation.of.
bioactive.molecules,.modification.of.the.porosity,.crystallinity,.and.biodegradability.may.be.obtained,.further.enlarging.the.potential.of.BNC.
Cell Adhesion
Surface.characteristics.play.a.vital.role.in.the.in.vivo.performance.of.biomaterials..The.fate.of.implants.is.determined.by.the.interactions,.to.a.large.extent.
cell.specific,.between.the.biomaterial.and.tissues.(Chu.et.al..2002)..Polymeric.
materials.do.not.always.possess.the.specific.bioactivity.required.to.promote.
91
Bacterial Cellulose Surface Modifications
João P. Silva, Fábia K. Andrade, and Francisco Miguel Gama
Center of Biological Engineering, Institute for Biotechnology and
Bioengineering, University of Minho, Braga, Portugal
CONTENTS
Cell.Adhesion......................................................................................................... 91
Biodegradation....................................................................................................... 97
Incorporation.of.Antimicrobial.Agents. ............................................................ 100
Enzyme.Immobilization. ..................................................................................... 101
Immobilization.of.Cells....................................................................................... 103
Modifications.for.Optoelectronic.Devices........................................................ 104
Hydrophobic.Derivatives................................................................................... 105
Precipitation.of.Metal.Ions. ................................................................................. 106
Acknowledgment. ................................................................................................ 107
References. ............................................................................................................. 108
The.unique.properties.of.bacterial.nanocellulose.(BNC).provide.the.basis.
for.a.wide.range.of.applications.in.human.and.veterinary.medicine,.odontology,.pharmaceuticals,.acoustic.and.filter.membranes,.biotechnological.
devices,.and.in.the.food.and.paper.industry..In.this.chapter,.an.overview.
of. surface. modifications. of. bacterial. cellulose.is.presented..Depending.
on.the.envisaged.applications,.chemical.modifications,.incorporation.of.
bioactive.molecules,.modification.of.the.porosity,.crystallinity,.and.biodegradability.may.be.obtained,.further.enlarging.the.potential.of.BNC.
Cell Adhesion
Surface.characteristics.play.a.vital.role.in.the.in.vivo.performance.of.biomaterials..The.fate.of.implants.is.determined.by.the.interactions,.to.a.large.extent.
cell.specific,.between.the.biomaterial.and.tissues.(Chu.et.al..2002)..Polymeric.
materials.do.not.always.possess.the.specific.bioactivity.required.to.promote.
91