311
Tumor Formation and Regulation in Xenopus
Slater, R. T. et al. (2019) ‘Radiographic and ultrasonographic
appearance of pneumonia in a frog’, Veterinary Radiology
and Ultrasound, 62(4), pp. 35–39. doi: 10.1111/vru.12796.
Smith, A. C. H. et al. (2010) ‘High-throughput cell transplantation
establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia’, Blood, 115(16),
pp. 3296–3303. doi: 10.1182/blood-2009-10-246488.
Snyder, C. S. et al. (2009) ‘Complementarity of ultrasound and f uorescence imaging in an orthotopic mouse model of pancreatic cancer’, BMC Cancer, 9(1), p. 106. doi: 10.1186/1471-2407-9-106.
Sprague, J. et al. (2008) ‘The Zebrafsh information network: The
zebrafsh model organism database provides expanded support for genotypes and phenotypes’, Nucleic Acids Research,
36(Suppl. 1), pp. D768–D772. doi: 10.1093/nar/gkm956.
Stacy, B. A. and Parker, J. M. (2004) ‘Amphibian oncology’, in
Veterinary Clinics of North America: Exotic Animal Practice,
7(3), pp. 673–695. doi: 10.1016/j.cvex.2004.04.001.
Stewart, T. A., Pattengale, P. K. and Leder, P. (1984) ‘Spontaneous
mammary adenocarcinomas in transgenic mice that carry
and express MTV/myc fusion genes’, Cell, 38(3), pp. 627–
637. doi: 10.1016/0092-8674(84)90257-5.
Suzuki, M. et al. (2020) ‘Spontaneous neoplasia in the western
clawed frog Xenopus tropicalis’, microPublication biology,
2020. doi: 10.17912/micropub.biology.000294.
Tanaka, M. et al. (2016) ‘Identifcation of anti-cancer chemical compounds using Xenopus embryos’, Cancer Science,
107(6), pp. 803–811. doi: 10.1111/cas.12940.
Tandon, P. et al. (2017) ‘Expanding the genetic toolkit in Xenopus:
Approaches and opportunities for human disease modeling’, in Developmental Biology, 426(2), pp. 325–335. doi:
10.1016/j.ydbio.2016.04.009.
Tang, Q. et al. (2014) ‘Optimized cell transplantation using adult
rag2 mutant zebrafsh’, Nature Methods, 11(8), pp. 821–824.
doi: 10.1038/nmeth.3031.
Taube, J. M. et al. (2014) ‘Association of PD-1, PD-1 ligands,
and other features of the tumor immune microenvironment with response to anti-PD-1 therapy’, Clinical Cancer
Research, 20(19), pp. 5064–5074. doi: 10.1158/1078-0432.
CCR-13-3271.
Tsherniak, A. et al. (2017) ‘Defning a cancer dependency map’,
Cell, 170(3), pp. 564–576.e16. doi: 10.1016/j.cell.2017.
06.010.
Tulkens, D. et al. (2021) ‘Engraftment of allotransplanted tumour
cells in adult rag2 mutant Xenopus tropicalis’, BioRxiv,
doi:10.1101/2021.11.15.468684
Tzelepis, K. et al. (2016) ‘A CRISPR dropout screen identifes genetic vulnerabilities and therapeutic targets in acute
myeloid leukemia’, Cell Reports, 17(4), pp. 1193–1205. doi:
10.1016/j.celrep.2016.09.079.
Vakoc, B. J. et al. (2012) ‘Cancer imaging by optical coherence
tomography: Preclinical progress and clinical potential’,
Nature Reviews Cancer, 12(5), pp. 363–368. doi: 10.1038/
nrc3235.
Van Nieuwenhuysen, T. et al. (2015) ‘TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous
polyposis’, Oncoscience, 2(5), pp. 555–566. doi: 10.18632/
oncoscience.166.
Wallingford, J. B. (1999) ‘Tumors in tadpoles: The Xenopus
embryo as a model system for the study of tumorigenesis’,
Trends in Genetics, 15(10), pp. 385–388. doi: 10.1016/
S0168-9525(99)01800-4.
Wallingford, J. B. et al. (1997) ‘p53 activity is essential for normal
development in Xenopus’, Current Biology, 7(10), pp. 747–
757. doi: 10.1016/S0960-9822(06)00333-2.
Watson, A. L. et al. (2016) ‘Engineered swine models of cancer’,
Frontiers in Genetics, 7, p. 78. doi: 10.3389/fgene.2016.00078.
Wheeler, G. N. and Brändli, A. W. (2009) ‘Simple vertebrate models for chemical genetics and drug discovery screens: Lessons
from zebrafsh and Xenopus’, Developmental Dynamics,
238(6), pp. 1287–1308. doi: 10.1002/dvdy.21967.
Wheeler, G. N. and Liu, K. J. (2012) ‘ Xenopus : An ideal system
for chemical genetics’, Genesis, 50(3), pp. 207–218. doi:
10.1002/dvg.22009.
White, R., Rose, K. and Zon, L. (2013) ‘Zebrafsh cancer: The state
of the art and the path forward’, Nature Reviews Cancer,
13(9), pp. 624–636. doi: 10.1038/nrc3589.
Xiao, A. et al. (2002) ‘Astrocyte inactivation of the pRb pathway
predisposes mice to malignant astrocytoma development
that is accelerated by PTEN mutation’, Cancer Cell, 1(2),
pp. 157–168. doi: 10.1016/S1535-6108(02)00029-6.
Yamagiwa, K. and Ichikawa, K. (1918) ‘Experimental study of the
pathogenesis of carcinoma’, Journal of Cancer Research,
3(1), pp. 1–29. doi: 10.1158/jcr.1918.1.
Yan, C. et al. (2019) ‘Visualizing engrafted human cancer and therapy responses in immunodef cient Zebraf sh’, Cell, 177(7),
pp. 1903–1914.e14. doi: 10.1016/j.cell.2019.04.004.
Yang, J. et al. (2020) ‘Guidelines and defnitions for research
on epithelial-mesenchymal transition’, Nature Reviews in
Molecular and Cellular Biology, 21(6), pp. 341–352. doi:
10.1038/s41580-020-0237-9.
Yang, S. et al. (1998) ‘Overexpression of a novel Xenopus Rel
mRNA induces tumors in early embryos’, Journal of
Biological Chemistry, 273(22), pp. 13746–13752. doi: 10.
1074/jbc.273.22.13746.
Zhang, F. et al. (2015) ‘Antibiotic toxicity and absorption in
Zebrafsh using liquid chromatography-tandem mass spectrometry’, PLoS One, 10(5), p. e0124805. doi: 10.1371/journal.pone.0124805.
Zuckermann, M. et al. (2015) ‘Somatic CRISPR/Cas9-mediated
tumour suppressor disruption enables versatile brain tumour
modelling’, Nature Communications, 6, p. 7391. doi: 10.1038/
ncomms8391.
Tumor Formation and Regulation in Xenopus
Slater, R. T. et al. (2019) ‘Radiographic and ultrasonographic
appearance of pneumonia in a frog’, Veterinary Radiology
and Ultrasound, 62(4), pp. 35–39. doi: 10.1111/vru.12796.
Smith, A. C. H. et al. (2010) ‘High-throughput cell transplantation
establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia’, Blood, 115(16),
pp. 3296–3303. doi: 10.1182/blood-2009-10-246488.
Snyder, C. S. et al. (2009) ‘Complementarity of ultrasound and f uorescence imaging in an orthotopic mouse model of pancreatic cancer’, BMC Cancer, 9(1), p. 106. doi: 10.1186/1471-2407-9-106.
Sprague, J. et al. (2008) ‘The Zebrafsh information network: The
zebrafsh model organism database provides expanded support for genotypes and phenotypes’, Nucleic Acids Research,
36(Suppl. 1), pp. D768–D772. doi: 10.1093/nar/gkm956.
Stacy, B. A. and Parker, J. M. (2004) ‘Amphibian oncology’, in
Veterinary Clinics of North America: Exotic Animal Practice,
7(3), pp. 673–695. doi: 10.1016/j.cvex.2004.04.001.
Stewart, T. A., Pattengale, P. K. and Leder, P. (1984) ‘Spontaneous
mammary adenocarcinomas in transgenic mice that carry
and express MTV/myc fusion genes’, Cell, 38(3), pp. 627–
637. doi: 10.1016/0092-8674(84)90257-5.
Suzuki, M. et al. (2020) ‘Spontaneous neoplasia in the western
clawed frog Xenopus tropicalis’, microPublication biology,
2020. doi: 10.17912/micropub.biology.000294.
Tanaka, M. et al. (2016) ‘Identifcation of anti-cancer chemical compounds using Xenopus embryos’, Cancer Science,
107(6), pp. 803–811. doi: 10.1111/cas.12940.
Tandon, P. et al. (2017) ‘Expanding the genetic toolkit in Xenopus:
Approaches and opportunities for human disease modeling’, in Developmental Biology, 426(2), pp. 325–335. doi:
10.1016/j.ydbio.2016.04.009.
Tang, Q. et al. (2014) ‘Optimized cell transplantation using adult
rag2 mutant zebrafsh’, Nature Methods, 11(8), pp. 821–824.
doi: 10.1038/nmeth.3031.
Taube, J. M. et al. (2014) ‘Association of PD-1, PD-1 ligands,
and other features of the tumor immune microenvironment with response to anti-PD-1 therapy’, Clinical Cancer
Research, 20(19), pp. 5064–5074. doi: 10.1158/1078-0432.
CCR-13-3271.
Tsherniak, A. et al. (2017) ‘Defning a cancer dependency map’,
Cell, 170(3), pp. 564–576.e16. doi: 10.1016/j.cell.2017.
06.010.
Tulkens, D. et al. (2021) ‘Engraftment of allotransplanted tumour
cells in adult rag2 mutant Xenopus tropicalis’, BioRxiv,
doi:10.1101/2021.11.15.468684
Tzelepis, K. et al. (2016) ‘A CRISPR dropout screen identifes genetic vulnerabilities and therapeutic targets in acute
myeloid leukemia’, Cell Reports, 17(4), pp. 1193–1205. doi:
10.1016/j.celrep.2016.09.079.
Vakoc, B. J. et al. (2012) ‘Cancer imaging by optical coherence
tomography: Preclinical progress and clinical potential’,
Nature Reviews Cancer, 12(5), pp. 363–368. doi: 10.1038/
nrc3235.
Van Nieuwenhuysen, T. et al. (2015) ‘TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous
polyposis’, Oncoscience, 2(5), pp. 555–566. doi: 10.18632/
oncoscience.166.
Wallingford, J. B. (1999) ‘Tumors in tadpoles: The Xenopus
embryo as a model system for the study of tumorigenesis’,
Trends in Genetics, 15(10), pp. 385–388. doi: 10.1016/
S0168-9525(99)01800-4.
Wallingford, J. B. et al. (1997) ‘p53 activity is essential for normal
development in Xenopus’, Current Biology, 7(10), pp. 747–
757. doi: 10.1016/S0960-9822(06)00333-2.
Watson, A. L. et al. (2016) ‘Engineered swine models of cancer’,
Frontiers in Genetics, 7, p. 78. doi: 10.3389/fgene.2016.00078.
Wheeler, G. N. and Brändli, A. W. (2009) ‘Simple vertebrate models for chemical genetics and drug discovery screens: Lessons
from zebrafsh and Xenopus’, Developmental Dynamics,
238(6), pp. 1287–1308. doi: 10.1002/dvdy.21967.
Wheeler, G. N. and Liu, K. J. (2012) ‘ Xenopus : An ideal system
for chemical genetics’, Genesis, 50(3), pp. 207–218. doi:
10.1002/dvg.22009.
White, R., Rose, K. and Zon, L. (2013) ‘Zebrafsh cancer: The state
of the art and the path forward’, Nature Reviews Cancer,
13(9), pp. 624–636. doi: 10.1038/nrc3589.
Xiao, A. et al. (2002) ‘Astrocyte inactivation of the pRb pathway
predisposes mice to malignant astrocytoma development
that is accelerated by PTEN mutation’, Cancer Cell, 1(2),
pp. 157–168. doi: 10.1016/S1535-6108(02)00029-6.
Yamagiwa, K. and Ichikawa, K. (1918) ‘Experimental study of the
pathogenesis of carcinoma’, Journal of Cancer Research,
3(1), pp. 1–29. doi: 10.1158/jcr.1918.1.
Yan, C. et al. (2019) ‘Visualizing engrafted human cancer and therapy responses in immunodef cient Zebraf sh’, Cell, 177(7),
pp. 1903–1914.e14. doi: 10.1016/j.cell.2019.04.004.
Yang, J. et al. (2020) ‘Guidelines and defnitions for research
on epithelial-mesenchymal transition’, Nature Reviews in
Molecular and Cellular Biology, 21(6), pp. 341–352. doi:
10.1038/s41580-020-0237-9.
Yang, S. et al. (1998) ‘Overexpression of a novel Xenopus Rel
mRNA induces tumors in early embryos’, Journal of
Biological Chemistry, 273(22), pp. 13746–13752. doi: 10.
1074/jbc.273.22.13746.
Zhang, F. et al. (2015) ‘Antibiotic toxicity and absorption in
Zebrafsh using liquid chromatography-tandem mass spectrometry’, PLoS One, 10(5), p. e0124805. doi: 10.1371/journal.pone.0124805.
Zuckermann, M. et al. (2015) ‘Somatic CRISPR/Cas9-mediated
tumour suppressor disruption enables versatile brain tumour
modelling’, Nature Communications, 6, p. 7391. doi: 10.1038/
ncomms8391.