Publications du PNEAT
Amzil Z., 1993. L'acide okadaïque: optimisation
de la purification; nouvel le méthode de
détection biologique. Th. Univ. Nantes, 6. 12,
234 p.
Amzil Z, Pouchus Y.F., Verbist j .-F., Lassus
P. Modelization of bioactive compounds purifi cation : optimisation of production of okaclaie acic and DTX-1 from Prorocentrum lima.
j. Pharm. Sc. (proposé pour publication).
Bansard S., Vernoux j.-P., Chesnais j.-M., Sauviat
M.P., Simon j.-F., Le Baut C., 1995. Preliminary separation and characteri zation of a sidetoxic extract obta ined in addition to okadaic
acid in Dinophysis sp. contam inated mussels.
ln : Harmful Mari ne Algal Blooms. Lassus P.,
Arzu l G., Erard E., Gentien P., Marcaillou-Le
Baut C. Lavoisier, Publish . lntercept. Ltd., 267272.
Diogene G., 1993. Cytotoxicité aspécifique et
spécifique de la maïtotoxine et d'extraits du
dinoflagell é Cambierdiscus toxicus. Thèse
Univ. Paris VIl, 159 p.
Références bibliographiques
Bagnis R., Chanteau S., Chungue E., Hurtel j.-M.,
Yasumoto T., 1980. Origi ns of ciguatera fish
poisoning :a new dinoflagellate Cambierdiscus toxicus Adach i et Fukuyo, definitely involved as a causal agent. Toxicon, 18 (2), 199-208 .
Benesath F.A., Dickey R.W., 1991. Mass spectral
characteristics of okadaic ac id and simple
derivatives. Rapid Commun. Mass Spectrom.,
5 (6), 283-290.
Dickey R.W., Mi ller D.M ., Tindall D.R., 1984.
Extraction of a water-sol uble toxin from a
dinoflagellate, Cambierdiscus tox icus. ln :
Seafood Toxins. Ragelis E.P., Ed, ACS Symp.
series, 262, 257-269.
Chimie extractive
Diogene G., Dubreuil A., Breittmayer j.-P. , Pu iseux-Dao S., 1994. Cytotoxic quantification of
maitotoxin-like activity from the dinoflagellate Cambierdiscus toxicus. Toxic. ln Vitro, 8 (1 ),
37-45.
Morlaix M., Lassus P., 1992. Influence de l'azote
et du phosphore sur la croissance et la toxicité de Prorocentrum lima (Ehrenberg) Dodge.
Cryptogamie, Algologie, 13 (3), 187-195.
Sauviat M.P., Vernoux j.-P., Marcaillou-Le Baut C.,
Bansa rd S., Hamelin M., 1996. Effect of an
unknow n toxin isolated from Dinophysis sp.
contaminated french mussels on the electrical
and mechanical activity of frog heart., Nat.
Toxins, 4, 80-84.
Vernoux j.-P., Bansard S., Simon j .-F., NwaiAmang D., Le Baut C., Gleizes E., Fremy j.M., Lasne M.C., 1994. Cooked mussels contaminated by Dinophysis sp. : a source of okaclaie acid. Nat. Toxins, 2, 184-188.
Lee j .-S. , lgaras hi T., Fraga S., Dahl E., Hovgaard P., Yasu moto T., 1980. Determination of
diarrheic shellfish toxins in various d inoflagellate species. j .Applied Phycol., 1, 147-152 .
Underdal B., Yndestad M., Aune T., 1985. DSP
intoxication in Norway and Sweden, automn
1984-spring 1985. ln : Toxic Dinoflagellates,
Anderson D.M., WhiteA.M., Baden D.G., Eds,
Elsevier Sei. Publ ish., 489-494.
Yokoyama A., Mu rata M., Oshima Y., lwashita T.,
Yasumoto T., 1988. Sorne chemical properties
of maitotoxin, a putative calcium channel agonist isolated from a marine dinoflagellate.
j.Biochemistry, 104, 184-187.
147
Amzil Z., 1993. L'acide okadaïque: optimisation
de la purification; nouvel le méthode de
détection biologique. Th. Univ. Nantes, 6. 12,
234 p.
Amzil Z, Pouchus Y.F., Verbist j .-F., Lassus
P. Modelization of bioactive compounds purifi cation : optimisation of production of okaclaie acic and DTX-1 from Prorocentrum lima.
j. Pharm. Sc. (proposé pour publication).
Bansard S., Vernoux j.-P., Chesnais j.-M., Sauviat
M.P., Simon j.-F., Le Baut C., 1995. Preliminary separation and characteri zation of a sidetoxic extract obta ined in addition to okadaic
acid in Dinophysis sp. contam inated mussels.
ln : Harmful Mari ne Algal Blooms. Lassus P.,
Arzu l G., Erard E., Gentien P., Marcaillou-Le
Baut C. Lavoisier, Publish . lntercept. Ltd., 267272.
Diogene G., 1993. Cytotoxicité aspécifique et
spécifique de la maïtotoxine et d'extraits du
dinoflagell é Cambierdiscus toxicus. Thèse
Univ. Paris VIl, 159 p.
Références bibliographiques
Bagnis R., Chanteau S., Chungue E., Hurtel j.-M.,
Yasumoto T., 1980. Origi ns of ciguatera fish
poisoning :a new dinoflagellate Cambierdiscus toxicus Adach i et Fukuyo, definitely involved as a causal agent. Toxicon, 18 (2), 199-208 .
Benesath F.A., Dickey R.W., 1991. Mass spectral
characteristics of okadaic ac id and simple
derivatives. Rapid Commun. Mass Spectrom.,
5 (6), 283-290.
Dickey R.W., Mi ller D.M ., Tindall D.R., 1984.
Extraction of a water-sol uble toxin from a
dinoflagellate, Cambierdiscus tox icus. ln :
Seafood Toxins. Ragelis E.P., Ed, ACS Symp.
series, 262, 257-269.
Chimie extractive
Diogene G., Dubreuil A., Breittmayer j.-P. , Pu iseux-Dao S., 1994. Cytotoxic quantification of
maitotoxin-like activity from the dinoflagellate Cambierdiscus toxicus. Toxic. ln Vitro, 8 (1 ),
37-45.
Morlaix M., Lassus P., 1992. Influence de l'azote
et du phosphore sur la croissance et la toxicité de Prorocentrum lima (Ehrenberg) Dodge.
Cryptogamie, Algologie, 13 (3), 187-195.
Sauviat M.P., Vernoux j.-P., Marcaillou-Le Baut C.,
Bansa rd S., Hamelin M., 1996. Effect of an
unknow n toxin isolated from Dinophysis sp.
contaminated french mussels on the electrical
and mechanical activity of frog heart., Nat.
Toxins, 4, 80-84.
Vernoux j.-P., Bansard S., Simon j .-F., NwaiAmang D., Le Baut C., Gleizes E., Fremy j.M., Lasne M.C., 1994. Cooked mussels contaminated by Dinophysis sp. : a source of okaclaie acid. Nat. Toxins, 2, 184-188.
Lee j .-S. , lgaras hi T., Fraga S., Dahl E., Hovgaard P., Yasu moto T., 1980. Determination of
diarrheic shellfish toxins in various d inoflagellate species. j .Applied Phycol., 1, 147-152 .
Underdal B., Yndestad M., Aune T., 1985. DSP
intoxication in Norway and Sweden, automn
1984-spring 1985. ln : Toxic Dinoflagellates,
Anderson D.M., WhiteA.M., Baden D.G., Eds,
Elsevier Sei. Publ ish., 489-494.
Yokoyama A., Mu rata M., Oshima Y., lwashita T.,
Yasumoto T., 1988. Sorne chemical properties
of maitotoxin, a putative calcium channel agonist isolated from a marine dinoflagellate.
j.Biochemistry, 104, 184-187.
147