390
D. HAROLD COPP
Table III
Calcitonin Concentration in Glands from Various Vertebrates"
Units (MRC)/g fresh gland wt
UltimoInternal
Unit/kg
Class and species
Thyroid branchial parathyroid
body wt
Mammalia
Man, Homo sapiens
Normal thyroid
Medullary cell carcinoma
of thyroid
Rat, Rattus rattus
Hog, Sus scrofa
Dog, Canis familiaris
Rabbit, Oryctolagus
cuniculus
Lower pole
Upper pole
Aves
Domestic fowl, Gallus
Turkey, Meleagra gallopavo
dwnestica
Reptilia
Turtle, Pseudemys
concinna suwaniensis
Amphibia
Bullfrog, Rana catesbeiana
Chum salmon,
Gray cod, Gadus
Teleosti
Oncorhynchus keta
macrocephalus
Dogfish shark, Squalus
Elasmobranchii
suckleyi
0.4
17
5-15
2-5
1 4
1 .5-2
b
b
b
b
-
-
-
b
-
-
-
-
-
-
-
30-120
60-100
3-9
0.5-0.8
2 5 4 0
10-20
25-35
0.16
-
0 . 2 4 . 6
0.4-0.8
0.25-0.50
-
-
0.5-0.8
0.5-0.9
0.002-0.006
0.001-0.002
O.PO.6
0.2-0.4
0 . 2 5 4 . 4 0
a Data from this laboratory, including that reported by Copp and Parkes (1968).
Table taken from review by Copp (1968b). Reproduced through the courtesy of Cambridge Univ. Press, London.
No detectable hypocalcemic activity.
CBased on an estimated content of 0.5-2.4 U/g dry weight (Galante el al., 1968).
malian thyroid. It is interesting to note that the total calcitonin content
per kilogram body weight was similar in the elasmobranchs, teleosts,
birds, and mammals studied. The much lower values in the turtle and
bullfrog may represent a seasonal variation.
D. HAROLD COPP
Table III
Calcitonin Concentration in Glands from Various Vertebrates"
Units (MRC)/g fresh gland wt
UltimoInternal
Unit/kg
Class and species
Thyroid branchial parathyroid
body wt
Mammalia
Man, Homo sapiens
Normal thyroid
Medullary cell carcinoma
of thyroid
Rat, Rattus rattus
Hog, Sus scrofa
Dog, Canis familiaris
Rabbit, Oryctolagus
cuniculus
Lower pole
Upper pole
Aves
Domestic fowl, Gallus
Turkey, Meleagra gallopavo
dwnestica
Reptilia
Turtle, Pseudemys
concinna suwaniensis
Amphibia
Bullfrog, Rana catesbeiana
Chum salmon,
Gray cod, Gadus
Teleosti
Oncorhynchus keta
macrocephalus
Dogfish shark, Squalus
Elasmobranchii
suckleyi
0.4
17
5-15
2-5
1 4
1 .5-2
b
b
b
b
-
-
-
b
-
-
-
-
-
-
-
30-120
60-100
3-9
0.5-0.8
2 5 4 0
10-20
25-35
0.16
-
0 . 2 4 . 6
0.4-0.8
0.25-0.50
-
-
0.5-0.8
0.5-0.9
0.002-0.006
0.001-0.002
O.PO.6
0.2-0.4
0 . 2 5 4 . 4 0
a Data from this laboratory, including that reported by Copp and Parkes (1968).
Table taken from review by Copp (1968b). Reproduced through the courtesy of Cambridge Univ. Press, London.
No detectable hypocalcemic activity.
CBased on an estimated content of 0.5-2.4 U/g dry weight (Galante el al., 1968).
malian thyroid. It is interesting to note that the total calcitonin content
per kilogram body weight was similar in the elasmobranchs, teleosts,
birds, and mammals studied. The much lower values in the turtle and
bullfrog may represent a seasonal variation.