340
CHESTER JONES, CHAN, HENDERSON, AND BALL
Time (hours)
Fig. 5. Effect of adrenalectomy on the development of a “sodium extrusion pump”
in the gills on transfer of the eel from freshwater ( F W ) to seawater (SW). (0)
sham operated, n = 6; ( 0 ) adrenalectomized, n = 6. ( Mayer et al., 1967.)
) .
>
0
0 0
U
L
.c
.e
0
0
c
a
0.06
0
2
4
6
0
0
2
4
6
8
( 0 )
(b)
Ti me :(hours)
Fig. 6. Effect of adrenalectomy (Adx) f cortisol injection on the rate of sodium
efflux in the seawater eel. ( a ) The rate of appearance of radioactively labeled sodium
(*”a or “a) in the water following injection of the radioactive isotope at time zero.
( b ) Analysis of the results in ( a ) showing that the rate of sodium turnover is much
slower in the adrenalectomized animal compared to that of the sham-operated control
animal receiving cortisol. Data from Mayer et al. ( 1967). TW = biological half-life;
k = flux constant or fraction of internal pool of sodium being exchanged per hour.