6
THE ADRENOCORTICAL STEROIDS.
ADRENOCORTICOTROPIN AND THE
CORPUSCLES OF STANNIUS
I . C H E S T E R ]ONES. D . K . 0 . C H A N . 1 . W . HENDERSON.
and I . N . BALL
I . Introduction . . . . . . . . . . . 322
A . The Adrenal Cortex . . . . . . . . . 322
B . The Adrenocortical Hormones . . . . . . . 323
I1 . Adrenocorticosteroids in Fish . . . . . . . . 323
A . Adrenocorticosteroids in Plasma . . . . . . . 323
B . Biogenesis of Adrenocorticosteroids . . . . . . 328
331
A . General Considerations . . . . . . . . 331
B . Osmoregulation . . . . . . . . . . 332
C . Effects of Pharmacological Induction of Adrenocortical
Insufficiency . . . . . . . . . . . 345
D . Protein and Carbohydrate Metabolism . . . . . 346
E . Effects on Blood Cells . . .
. . . . . 348
IV . The Pituitary-Adrenocortical Axis . . . . . . . 349
A . General Considerations . . . . . . . . 349
B . Biochemistry of ACTH . . . . . . . . 349
C . ACTH in Teleost Fishes . . . . . . . . 350
V . Extra-adrenocortical Activity of ACTH . . . . . . 352
A . ACTH and Osmoregulation . . . . . . . . 352
VI . Other Factors Affecting Adrenocorticosteroid Levels in Plasma . 355
VII . Corpuscles of Stannius . . . . . . . . . 356
A . Presence of Renin Activity . . . . . . . . 356
B . Corpuscles of Stannius and Osmoregulation . . . . 358
C . Factors Controlling the Corpuscles of Stannius . . . . 363
VIII . Conclusions . . . . . . . . . . . . 364
References . . . . . . . . . . . . . 364
C . The Corpuscles of Stannius and Steroidogenesis . . . 330
I11 . Physiological Role of the Adrenal Cortical Secretions . . .
D . ACTH in Elasmobranch and Cyclostome Fishes . . . 351
321