78
VICTOR L. LOOSANOFF AND HARRY C. DAVIS
complete mortality of larvae within 12 hr (Fig. 27). Later, these strains
were reisolated from moribund larvae to satisfy Koch’s postulates.
These studies are still in progress and it appears that the recent isolation deals with different clones from those observed by Guillard.
FIQ. 27. Effect of pathogenic bacteria upon larvae of Mercenaria mercenuriu. Healthy
larvae (above) ; larvae from the same culture 12 hr after inoculation (below). Largmt
larvae in this photomicrograph are approximateIy 160 p long.
Following recognition of the pathogenicity of fungi and bacteria
we began testing a number of antibiotics and fungicides, in addition
to using physical measures for prevention of diseases,
determine
their effects on suryival and growth of larvae (Davis and Chanley,
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