5. ANTIBIOSIS AND ANTIBIOTICS
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CH 2 OH
OH
OH
α-τ>- glue ose
α-D-glucosamine
Trehalosamine
(I)
CH 2 NH 2
NH 2
NH
streptidine
streptose
JV-methyl-L-glucosamine
streptobiosamine
Streptomycin
0
α-D-glucosamine
2-deoxystreptamine
p-ribose
paromose
paromamine
paromobiosamine
Paromomycin
(IV)
α In kanamycin B, 6-glucosamine is replaced by an undetermined ninhydrinpositive compound.
1 In dihydrostreptomycin, the CHO of streptose is replaced by CH 2 OH and, in
hydroxystreptomycin, its CH 3 is replaced by CH 2 OH. In mannosidostreptomycin,
ß-D-mannose is linked to N-methyl-L-glucosamine.