228
CHARLES S. THORNTON
Days of
regeneration
FIG. 4. Graphic representation of the mitotic index and cell density distribution
of four zones in blastemata of 14, 16, and 18 days after limb amputation. The apical
cap was moved on day 10 to an asymmetric position. Zone 1 represents the position
of the apical cap after moving it; zone 3 represents the original position of the
apical cap; zone 2 represents the basal quadrant of the blastema; zone 4 represents
the area of the blastema nearest the site where the skin excision was made and
which becomes healed with a thick wound epithelium. Note the high mitotic index
in the area beneath the apical cap in zone 1 and, in day 14 blastemata, in zone 3
where the cap originally was located. In blastemata of 16 and 18 days (6 and 8
days after cap shifting) the mitotic index in zone 3 drops. (From Hearson, 1966.)
j i u n j a d s 1 1 a D - A j i s u a f j - -
16
- M i t o t i c i n d e x —
18
14
Sample Areas
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