A
B
F I G . 1. Growth of the regeneration blastema of the forelimb of the axolotl,
Ambystoma
mexicanum. ( A ) The accumulation blastema, the "early bud" stage, at
10 days after amputation just above the elbow. Note the thickened epidermal wound
epithelium. ( B ) The "mound" stage blastema at 13 days after amputation. Note the
long epidermal tongue of cells extending out from the wound epithelium. The
mesenchymatous blastemal cells are densely clustered in the distal half of the bud.
(C) The "cone" blastema at 16 days after amputation. ( D ) The "paddle" stage
blastema at 19 days after amputation. Note that the inner core of blastemal cells
is undergoing the first steps in differentiation of the skeleton of the regenerate.
(Courtesy of Dr. Lester Hearson, Wabash College.)
C
D
208
B
F I G . 1. Growth of the regeneration blastema of the forelimb of the axolotl,
Ambystoma
mexicanum. ( A ) The accumulation blastema, the "early bud" stage, at
10 days after amputation just above the elbow. Note the thickened epidermal wound
epithelium. ( B ) The "mound" stage blastema at 13 days after amputation. Note the
long epidermal tongue of cells extending out from the wound epithelium. The
mesenchymatous blastemal cells are densely clustered in the distal half of the bud.
(C) The "cone" blastema at 16 days after amputation. ( D ) The "paddle" stage
blastema at 19 days after amputation. Note that the inner core of blastemal cells
is undergoing the first steps in differentiation of the skeleton of the regenerate.
(Courtesy of Dr. Lester Hearson, Wabash College.)
C
D
208