760
S U B J E C T I N D E X
Lysosomes,
acid phosphatase in, 311
o f chondrocytes, 309, 679
in dystrophic muscle, 311
hydrocortisone and, 611-12
hydrolases of, 380, 384, 679
proteolytic enzymes and, 3 0 9 , 3 8 1 , 6 1 1 ,
679
vitamin A and, 381, 383-4, 615, 679
M
Mackaness chamber, 39
Macronucleus (of Euplotes), 424
Macrophages,
active and resting, 172
as amoebocytes, 147, 159
arsenite and, 165
behaviour of, in plasma, 157
and colloid in thyroid, 602-3
and contact inhibition, 190
conversion of, to fibroblasts, 7, 165-6
cortisone and, 608
culture of isolated, 49
as depolarized cells, 184
ionic balance and, 167
movement of, 31, 145-6, 179, 182
in outgrowth o f thymus, 143
peripolesis and, 195
R N A turnover in, 328
ruffles on, 179
serum and, 157
steroids and, 167
synthesis o f protein in, 309
and vital dyes, 166
in vivo and in vitro, 2
Macrovilli, 158
Magnesium,
and cell adhesion, 53, 111
and cell cohesion, 52
and cell morphology, 111
essential requirement for, 2 5 - 6
and JVaegleria, 26, 166
and phosphatase, in cell division, 213
and re-aggregation, 499, 500
and synthesis o f D N A , 320
and trypsin, 10
Maintenance,
in vitro, 70
Malate,
and growth of blastulae, 577
M a l i c dehydrogenase, 263
Malignancy,
cell movement in, 191
development o f in clone, 6 6 - 7 , 168
tissue culture and, 4, 172
Malignant cells (see also T u m o u r Cells,
etc.),
D N A in, 324, 333
electrophoresis of, 46
glycolysis and, 267, 594
and hyaluronidase, 382-3
insulin and, 265, 593-4
invasiveness of, 382
latent period in growth of, 192
movement of, 191, 193
and mucopolysaccharides, 382
peripolesis and, 195
protein synthesis in, 333
radiation and, 7
relation to tissue-culture cells, 4, 168,
172
Malonate,
and development o f blastoderms, 571 - 2
and metabolism, 253, 571
and succinic dehydrogenase, 572
Malt extracts,
for inhibiting mesenchyme, 46
Maltose,
hydrolysis in medium, 247
as substitute for glucose, 566
M a m m a r y gland,
adipose tissue of, 634-5
cell cultures of, 298
corticosteroids and, 127, 635-6, 638-9
differentiation of, 478, 634
enzyme activity in cultures of, 298
hormones and function of, 127, 6 3 3 - 9
organ culture of, 128, 6 3 3 - 4
secretion in, 636
synthetic medium and function of, 127
tumours of, 434, 594, 638-9
M a m m o t r o p h i n (see also Prolactin),
634-6, 638-9
Manganese,
requirement for, 111, 282
Mannosamine,
and neuraminic acid, 358
Mannose,
in mucopolysaccharides, 358
as substitute for glucose, 244, 246, 566,
577
used b y lymphocytes, 128
S U B J E C T I N D E X
Lysosomes,
acid phosphatase in, 311
o f chondrocytes, 309, 679
in dystrophic muscle, 311
hydrocortisone and, 611-12
hydrolases of, 380, 384, 679
proteolytic enzymes and, 3 0 9 , 3 8 1 , 6 1 1 ,
679
vitamin A and, 381, 383-4, 615, 679
M
Mackaness chamber, 39
Macronucleus (of Euplotes), 424
Macrophages,
active and resting, 172
as amoebocytes, 147, 159
arsenite and, 165
behaviour of, in plasma, 157
and colloid in thyroid, 602-3
and contact inhibition, 190
conversion of, to fibroblasts, 7, 165-6
cortisone and, 608
culture of isolated, 49
as depolarized cells, 184
ionic balance and, 167
movement of, 31, 145-6, 179, 182
in outgrowth o f thymus, 143
peripolesis and, 195
R N A turnover in, 328
ruffles on, 179
serum and, 157
steroids and, 167
synthesis o f protein in, 309
and vital dyes, 166
in vivo and in vitro, 2
Macrovilli, 158
Magnesium,
and cell adhesion, 53, 111
and cell cohesion, 52
and cell morphology, 111
essential requirement for, 2 5 - 6
and JVaegleria, 26, 166
and phosphatase, in cell division, 213
and re-aggregation, 499, 500
and synthesis o f D N A , 320
and trypsin, 10
Maintenance,
in vitro, 70
Malate,
and growth of blastulae, 577
M a l i c dehydrogenase, 263
Malignancy,
cell movement in, 191
development o f in clone, 6 6 - 7 , 168
tissue culture and, 4, 172
Malignant cells (see also T u m o u r Cells,
etc.),
D N A in, 324, 333
electrophoresis of, 46
glycolysis and, 267, 594
and hyaluronidase, 382-3
insulin and, 265, 593-4
invasiveness of, 382
latent period in growth of, 192
movement of, 191, 193
and mucopolysaccharides, 382
peripolesis and, 195
protein synthesis in, 333
radiation and, 7
relation to tissue-culture cells, 4, 168,
172
Malonate,
and development o f blastoderms, 571 - 2
and metabolism, 253, 571
and succinic dehydrogenase, 572
Malt extracts,
for inhibiting mesenchyme, 46
Maltose,
hydrolysis in medium, 247
as substitute for glucose, 566
M a m m a r y gland,
adipose tissue of, 634-5
cell cultures of, 298
corticosteroids and, 127, 635-6, 638-9
differentiation of, 478, 634
enzyme activity in cultures of, 298
hormones and function of, 127, 6 3 3 - 9
organ culture of, 128, 6 3 3 - 4
secretion in, 636
synthetic medium and function of, 127
tumours of, 434, 594, 638-9
M a m m o t r o p h i n (see also Prolactin),
634-6, 638-9
Manganese,
requirement for, 111, 282
Mannosamine,
and neuraminic acid, 358
Mannose,
in mucopolysaccharides, 358
as substitute for glucose, 244, 246, 566,
577
used b y lymphocytes, 128