758
S U B J E C T I N D E X
L
Lentoids,
in cultures o f retinal cells, 473, 510,
513, 515
Leucaemic cells,
generation time, 422
(mouse), and folic acid, 115
and pyruvate, 289
respiration of, 252
thymidine and, 325
Leucine,
analogues of, and growth, 572-3
and bone rudiments, 304
in Eagle's meduim, 280
and heart tissue, 300
and keratinization, 305-6, 668
and kidney, 303
and liver, 303
and L-strain, 114
and mucous metaplasia, 668
and myoblasts, 113, 304
and prostate, 304
and serum proteins, 306
and tibia, 301
Leucocytes (white blood corpuscles),
as amoebocytes, 147, 159
for chromosome studies, 402
movement of, 145
in outgrowth from thymus, 143
phytohaemagglutinin and, 228
sex chromatin in, 399
survival in culture, 147
and survival o f cultures, 2, 86
vitamin G and, 681, 686
X-radiation and chromosomes of, 424
Limbs,
induced by bone marrow, 546
region o f embryo producing, 537
L i m b rudiments,
cells from, combined with mesonephros, 516
differentiation of, 6
dissociation and reaggregation, 492,
497, 506, 516
dissociation and redevelopment of, 62
D N A cycle in cells of, 338-9
parathormone etc. and, 649
Linolenic acid, 153
Lipid,
accumulation in brown fat, 595-7
and cell lines, 284
and cell membranes, 500
excretion of, 249
Lactate (Lactic acid),
and action o f insulin, 117, 594
in cultures o f embryos, 566, 577
and culture of lens, 80
and form of JVaegleria ,166
and growth hormone, 595
and mitotic rate, 594-5
p H and production of, 258
in place o f glucose, 112, 566, 577, 594
production in anaerobiosis, 24
production of, in culture, 250-1
and size of organ cultures, 81
vitamin A and production of, 677, 679
Lactic dehydrogenase,
absent from osteoclasts, 648
in cartilage,, 648
and oxygen tension, 264
Lactones,
and vitamin C, 681-2
Lag-phase, see Latent period
Lamelliform membranes,
of amoebocytes, 162
of astrocytes, 40, 148
of macrophages, 146
of Schwann cells, 152
Lanthionine,
as substitute for cystine, 300
Latent period (Lag-phase)
of activity in a culture, 192
protein-nitrogen in, 306
Lateral plate, 559
and fluoride, 571
incorporation of glycine by, 570
Leaching,
in cell cultures, 62, 124-5, 254, 285
of cells and tissues, 7, 29, 278
of Krebs-cycle intermediates, 254, 259
opposed b y embryo extract, 34
in perfusion methods, 80
and survival time, 84
Lens,
ascorbic acid in, 685
culture of, 80
induction of, 549
sources o f carbohydrate for, 245-6
Lens paper,
migration o f cells on, 77-8
for organ cultures, 73, 76-7, 79
rafts, 79
silicone-treated, 79
S U B J E C T I N D E X
L
Lentoids,
in cultures o f retinal cells, 473, 510,
513, 515
Leucaemic cells,
generation time, 422
(mouse), and folic acid, 115
and pyruvate, 289
respiration of, 252
thymidine and, 325
Leucine,
analogues of, and growth, 572-3
and bone rudiments, 304
in Eagle's meduim, 280
and heart tissue, 300
and keratinization, 305-6, 668
and kidney, 303
and liver, 303
and L-strain, 114
and mucous metaplasia, 668
and myoblasts, 113, 304
and prostate, 304
and serum proteins, 306
and tibia, 301
Leucocytes (white blood corpuscles),
as amoebocytes, 147, 159
for chromosome studies, 402
movement of, 145
in outgrowth from thymus, 143
phytohaemagglutinin and, 228
sex chromatin in, 399
survival in culture, 147
and survival o f cultures, 2, 86
vitamin G and, 681, 686
X-radiation and chromosomes of, 424
Limbs,
induced by bone marrow, 546
region o f embryo producing, 537
L i m b rudiments,
cells from, combined with mesonephros, 516
differentiation of, 6
dissociation and reaggregation, 492,
497, 506, 516
dissociation and redevelopment of, 62
D N A cycle in cells of, 338-9
parathormone etc. and, 649
Linolenic acid, 153
Lipid,
accumulation in brown fat, 595-7
and cell lines, 284
and cell membranes, 500
excretion of, 249
Lactate (Lactic acid),
and action o f insulin, 117, 594
in cultures o f embryos, 566, 577
and culture of lens, 80
and form of JVaegleria ,166
and growth hormone, 595
and mitotic rate, 594-5
p H and production of, 258
in place o f glucose, 112, 566, 577, 594
production in anaerobiosis, 24
production of, in culture, 250-1
and size of organ cultures, 81
vitamin A and production of, 677, 679
Lactic dehydrogenase,
absent from osteoclasts, 648
in cartilage,, 648
and oxygen tension, 264
Lactones,
and vitamin C, 681-2
Lag-phase, see Latent period
Lamelliform membranes,
of amoebocytes, 162
of astrocytes, 40, 148
of macrophages, 146
of Schwann cells, 152
Lanthionine,
as substitute for cystine, 300
Latent period (Lag-phase)
of activity in a culture, 192
protein-nitrogen in, 306
Lateral plate, 559
and fluoride, 571
incorporation of glycine by, 570
Leaching,
in cell cultures, 62, 124-5, 254, 285
of cells and tissues, 7, 29, 278
of Krebs-cycle intermediates, 254, 259
opposed b y embryo extract, 34
in perfusion methods, 80
and survival time, 84
Lens,
ascorbic acid in, 685
culture of, 80
induction of, 549
sources o f carbohydrate for, 245-6
Lens paper,
migration o f cells on, 77-8
for organ cultures, 73, 76-7, 79
rafts, 79
silicone-treated, 79