CARBON-CARBON BOND FORMING REACTIONS
75
I.B.2.a-7 Kitahara, T.
NC
OH 'Pr
et al., S, 693.
1. MsCl, TEA
CH 2 C1 2 , 50°C
2. 'Pr 2 NEt
''
HMPA, 180°C
NC
'Pr
54%
I.B.2.a-8 Bhuniya, D. and Singh, V.K., SC, 24, 374, 1475.
75%
e.e. = 82%
I.B.2.a-9 Masaki, Y. et al., CPB, 42, 179; Katz, T.J. et al., JOC, 59,
1889; Prandi, C. and Venturello, P., T, 50, 12463.
Ts
T \
AcO.
BF 3 «Et 2 0, Ac 2 0
L o H OH
CH 2 CI 2 , 0°C
Pr
I.B.2.a-10 Hayashi, T. et al.JX, 35, 4813.
R ^ ^ \ ^ O C 0 2 M e
[Pd]/(R)-MOP
SiEt,
HC0 2 H
proton sponge
O Ή OAc
81%
R
H^
SiEt 3
87-93%
e.e. = 60-91%
75
I.B.2.a-7 Kitahara, T.
NC
OH 'Pr
et al., S, 693.
1. MsCl, TEA
CH 2 C1 2 , 50°C
2. 'Pr 2 NEt
''
HMPA, 180°C
NC
'Pr
54%
I.B.2.a-8 Bhuniya, D. and Singh, V.K., SC, 24, 374, 1475.
75%
e.e. = 82%
I.B.2.a-9 Masaki, Y. et al., CPB, 42, 179; Katz, T.J. et al., JOC, 59,
1889; Prandi, C. and Venturello, P., T, 50, 12463.
Ts
T \
AcO.
BF 3 «Et 2 0, Ac 2 0
L o H OH
CH 2 CI 2 , 0°C
Pr
I.B.2.a-10 Hayashi, T. et al.JX, 35, 4813.
R ^ ^ \ ^ O C 0 2 M e
[Pd]/(R)-MOP
SiEt,
HC0 2 H
proton sponge
O Ή OAc
81%
R
H^
SiEt 3
87-93%
e.e. = 60-91%