CARBON-CARBON BOND FORMING REACTIONS
59
I.A.7.b.2-8 Reetz, M.T. and Kindler, A., CC, 2509; de Groot, A. et al,
T, 50, 10073.
Et 2 Mg, Cul
TMSC1, LiCI, -20°C
LA.7.b.2-9 Xu, L.-H. and Kundig, E.P., HCA, 77, 1480.
\/C0 2 Me
R3Li,MX n ^
R3 Kf°
2Me
R 2 \ ^ C i
THF, -70° to 0°C
~^2
\
80-94%
MX„ = CuBr«SMe 2 / ZnCl 2 or ZnCl 2
I.A.7.b.2-10 Yamamoto, H. et al., SL, 519 & JACS, 116, 4131;
Kabbara, J. et al., SL, 679.
ATPH, RLi
^.AA
YK
^
CF 3
Ph' ^
CF 3
82-97%
ATPH = aluminum tris(2,6-diphenylphenoxìde)
I.a.7.b.2-ll Bartoli, G. et al., TL, 35, 8651.
, N 0 2
R^
X N 0 2
RMgX
CeCl 3 ,THF y / V ^ 74-97%
59
I.A.7.b.2-8 Reetz, M.T. and Kindler, A., CC, 2509; de Groot, A. et al,
T, 50, 10073.
Et 2 Mg, Cul
TMSC1, LiCI, -20°C
LA.7.b.2-9 Xu, L.-H. and Kundig, E.P., HCA, 77, 1480.
\/C0 2 Me
R3Li,MX n ^
R3 Kf°
2Me
R 2 \ ^ C i
THF, -70° to 0°C
~^2
\
80-94%
MX„ = CuBr«SMe 2 / ZnCl 2 or ZnCl 2
I.A.7.b.2-10 Yamamoto, H. et al., SL, 519 & JACS, 116, 4131;
Kabbara, J. et al., SL, 679.
ATPH, RLi
^.AA
YK
^
CF 3
Ph' ^
CF 3
82-97%
ATPH = aluminum tris(2,6-diphenylphenoxìde)
I.a.7.b.2-ll Bartoli, G. et al., TL, 35, 8651.
, N 0 2
R^
X N 0 2
RMgX
CeCl 3 ,THF y / V ^ 74-97%