CARBON-CARBON BOND FORMING REACTIONS
55
I.A.7.b.l-9 lia, H., Junjappa, H. et al., JCS(Pl), 2439; see also: Toke,
L. et al., T, 50, 2895.
M e S s s ^
S M e
Ph.
Λ^-SMe
LDA
H O ^ V \ <
R
1
R
61-88%
other tandem Michael-Aldols reported
I.A.7.b.l-10 Marino, J.P., Paley, R.S. et al., JOC, 59, 3193.
/
p
·™ ♦ ><
\ y
H
NaH
E
THF
R
t p-Tol
E = C0 2 Et
K I
56-98%
E
80:20 to 100:0, E:Z
I.A.7.b.l-ll d'Angelo, J. et al., TL, 35, 9705 & TA, 5, 339; Pfau, M. et
al., TA, 5, 1459 & TL, 35, 1549.
co 0 2 Me
Mtu x Ph
[
T
60%
55
I.A.7.b.l-9 lia, H., Junjappa, H. et al., JCS(Pl), 2439; see also: Toke,
L. et al., T, 50, 2895.
M e S s s ^
S M e
Ph.
Λ^-SMe
LDA
H O ^ V \ <
R
1
R
61-88%
other tandem Michael-Aldols reported
I.A.7.b.l-10 Marino, J.P., Paley, R.S. et al., JOC, 59, 3193.
/
p
·™ ♦ ><
\ y
H
NaH
E
THF
R
t p-Tol
E = C0 2 Et
K I
56-98%
E
80:20 to 100:0, E:Z
I.A.7.b.l-ll d'Angelo, J. et al., TL, 35, 9705 & TA, 5, 339; Pfau, M. et
al., TA, 5, 1459 & TL, 35, 1549.
co 0 2 Me
Mtu x Ph
[
T
60%