CARBON-CARBON BOND FORMING REACTIONS
53
LA.7.b.l-3 Shibasaki, M. et al., JACS, 116, 1571; Kawara, A. and
Taguchi, T., TL, 35, 8805.
La-(S)-Binol
OMe
L i "
f r e e
,C0 2 Bn
100%, 75% ee
C0 2 Me
I.A.7.b.l-4 Yamaguchi, M. et al., TL, 35, 8233; Li, W.-S. et al., TL,
35, 6591 & 6595; Barco, A. et al., T, 50, 11743; Galambos, G., Szantay,
C. et al., H, 38, 1727.
R
2
+
HCHC1 3
-R
J
H"
R
1
NO,
^ N ^ * C 0 2 R b
R
N 0 2
47-91%, 29-84% ee
various other catalysts & substrates used for nitro aldols
I.A.7.b.l-5 Ruder, S.M. and Kulkarni, V.R., CC, 2119
o
o
o
o
II
,P(OEt) 2
γ ^ ^EWG
ho.«
^^^ryvr.1,2
T
base = NaOEt, KOH, 'BuOH
base, J O ( O E t ) 2
ROH I
h
C
Y
\ ^
EWG
Y = H, Cl; 58-79%
53
LA.7.b.l-3 Shibasaki, M. et al., JACS, 116, 1571; Kawara, A. and
Taguchi, T., TL, 35, 8805.
La-(S)-Binol
OMe
L i "
f r e e
,C0 2 Bn
100%, 75% ee
C0 2 Me
I.A.7.b.l-4 Yamaguchi, M. et al., TL, 35, 8233; Li, W.-S. et al., TL,
35, 6591 & 6595; Barco, A. et al., T, 50, 11743; Galambos, G., Szantay,
C. et al., H, 38, 1727.
R
2
+
HCHC1 3
-R
J
H"
R
1
NO,
^ N ^ * C 0 2 R b
R
N 0 2
47-91%, 29-84% ee
various other catalysts & substrates used for nitro aldols
I.A.7.b.l-5 Ruder, S.M. and Kulkarni, V.R., CC, 2119
o
o
o
o
II
,P(OEt) 2
γ ^ ^EWG
ho.«
^^^ryvr.1,2
T
base = NaOEt, KOH, 'BuOH
base, J O ( O E t ) 2
ROH I
h
C
Y
\ ^
EWG
Y = H, Cl; 58-79%