CARBON-CARBON BOND FORMING REACTIONS
39
I.A.7.a.3-15 Koert, U. et al., CB, 127, 1447; see also: Ohmori, H. et
al., CPB, 42, 1808; Sakamoto, T. et al., JOC, 59, 4717.
IZn
R-CHO
BF 3 'OEt 2 , CH 2 CI 2
-30 to 0°C
51-96%, 69:31 to 85:15
I.A.7.a.3-16 Rieke, R.D. et al., TL, 35, 7205; Jackson, R.F.W. et al.,
TL, 35, 4417; see also: Rollin, Y. et al., TL, 35, 5637.
Zn*
R-Br
THF
R-ZnX
R'COCl
►
CuCN, LiBr
THF
RCOR'
62-99%
R = 2° & 3° alkyl
similarly with Pd(0) catalysis or with electrogenerated Zn