CARBON-CARBON BOND FORMING REACTIONS
33
I.A.7.a.2-5 Falck, J.R., Mioskowski, C. et al., TL, 35, 5441; Caricato,
G. and Savoia, D., SL, 1015.
R
V
0 2 P h 1) Sml
* .
5£oH
R ^ S 0 2 P h
2)R
3
R
4
C=0 « Ί ώ θ 2 ^ 7 < 3
Jv
K
62-92%
ketones from a-lithiosulfones & chiral esters also reported
I.A.7.a.2-6 Julia, M. et al., BSF, 131, 639.
R^ ^OH
1) BuLi, THF
^Υ^
R
S °
2 R '
2)TBHP,-78°C
R ^ ^ S 0 2 R *
70-94%
I.A.7.a.3. Addition of Organometallic and Related Species
I.A.7.a.3-l Rieke, R.D. et al., SC, 24, 2379.
:O 2 H
1) Li, MgBr 2
2 ) C 0 2
Br
Br
99%
33
I.A.7.a.2-5 Falck, J.R., Mioskowski, C. et al., TL, 35, 5441; Caricato,
G. and Savoia, D., SL, 1015.
R
V
0 2 P h 1) Sml
* .
5£oH
R ^ S 0 2 P h
2)R
3
R
4
C=0 « Ί ώ θ 2 ^ 7 < 3
Jv
K
62-92%
ketones from a-lithiosulfones & chiral esters also reported
I.A.7.a.2-6 Julia, M. et al., BSF, 131, 639.
R^ ^OH
1) BuLi, THF
^Υ^
R
S °
2 R '
2)TBHP,-78°C
R ^ ^ S 0 2 R *
70-94%
I.A.7.a.3. Addition of Organometallic and Related Species
I.A.7.a.3-l Rieke, R.D. et al., SC, 24, 2379.
:O 2 H
1) Li, MgBr 2
2 ) C 0 2
Br
Br
99%