CARBON-CARBON BOND FORMING REACTIONS
31
I.A.7.a.la-24 Wong, C.-H. et al., TL, 35, 359 & JACS, 116, 558;
Fessner, W.-D. and Sinerius, G., AG(E), 33, 209.
|—OPO 3
1—OH
2N,
,CHO
1) RAMA
pH6.7
2) APase, pH 4.5
64% N,
ÖH O
18% N,
ÖH O
various other enzymatic aldols reported
I.A.7.a.la-25 Masuyama, Y. et al., BCJ, 67, 2265.
RCHO +
OAc
PdCl 2 (PhCN) 2
*SnCl 2 , MeCN
18-88%
I.A.7.a.2. Addition of N-. P-. S-. Se and Similar Stabilized
Carbanions
I.A.7.a.2-l Shibasaki, M. et al., TL, 35, 6123; see also: Ballini, R. and
Bosica, G., JOC, 59, 5466; see also: Demir, A.S. et al., S, 155.
OH
P h ^ Y
CHO
MeNO,
,NO,
NPhth
La-Li-(R)-BINOL
THF, -40°C
NPhth
92%, 96% ee