CARBON-CARBON BOND FORMING REACTIONS
29
I.A.7.a.la-18 Kiyooka, S. et al., TL, 35, 4107 & 5243.
OSiR 3
Ts-NV
R^HO + ==<
\ -
-78°C,3h
* L ^
XX
+
XX
53-70 %, 85-99 % ee 6-25 %, 39-72 % ee
the use of polymer supported chiral B promoters also reported
I.A.7.a.la-19 Mikami, K. and Matsukawa, S., JACS, 116, 4077; Crotti,
P. et al., G, 123, 673 (1993).
OTMS B I N O L . T .
O
OTMS
R
2
CHO + ==<
►
X
1
\ D 1
PhMe,0°C
R V ' ^ ^ ^ R
2
SR
1
47-96%%, 60-95% ee
LA.7.a.la-20 Dubac, J. et al., JOC, 59, 2238.
K < c „ o + W
T M S
^ ^
^^.
R i
\ R l
2)TMSX
R 1 ^ S < ^ R 4
R
f
R
3
X = Cl, Br, I
6 8-75%
29
I.A.7.a.la-18 Kiyooka, S. et al., TL, 35, 4107 & 5243.
OSiR 3
Ts-NV
R^HO + ==<
\ -
-78°C,3h
* L ^
XX
+
XX
53-70 %, 85-99 % ee 6-25 %, 39-72 % ee
the use of polymer supported chiral B promoters also reported
I.A.7.a.la-19 Mikami, K. and Matsukawa, S., JACS, 116, 4077; Crotti,
P. et al., G, 123, 673 (1993).
OTMS B I N O L . T .
O
OTMS
R
2
CHO + ==<
►
X
1
\ D 1
PhMe,0°C
R V ' ^ ^ ^ R
2
SR
1
47-96%%, 60-95% ee
LA.7.a.la-20 Dubac, J. et al., JOC, 59, 2238.
K < c „ o + W
T M S
^ ^
^^.
R i
\ R l
2)TMSX
R 1 ^ S < ^ R 4
R
f
R
3
X = Cl, Br, I
6 8-75%