22
ORGANIC SYNTHESIS—1995
I.A.6. Other Alkvlation Procedures
I.A.6-1 Nakamura, T. et al., T, 50, 11821; see also: Miura, T. and
Masaki, Y., JCS(Pl), 1659.
KCN
►
C
0-\
0
H-lyase
H ^
CN
>95% ee
H-lyase = cloned halohydrin hydrogen-halide lyase
substitution reactions of acetals with TMSCN also reported
I.A.6-2 Jaynes, B.S. and Hill, CL., JACS, 116, 12212.
polyoxotungstate
►
82%
I .A. 7. Nucleophilic Addition to Electrophilic Carbon
I.A.7.a. l a . Intermolecular Aldol-Tvpe 1.2-Additions
I.A.7.a.la-l Liotta, D.C. et al., TL, 35, 6029 and 4485; see also:
Ettmayer, P. et al., TL, 35, 3901.
w
X
^
l)NaHMDS
2) RCHO
NBn 2
N Bn 2 Me
-A*55-93%, >95%dr
ORGANIC SYNTHESIS—1995
I.A.6. Other Alkvlation Procedures
I.A.6-1 Nakamura, T. et al., T, 50, 11821; see also: Miura, T. and
Masaki, Y., JCS(Pl), 1659.
KCN
►
C
0-\
0
H-lyase
H ^
CN
>95% ee
H-lyase = cloned halohydrin hydrogen-halide lyase
substitution reactions of acetals with TMSCN also reported
I.A.6-2 Jaynes, B.S. and Hill, CL., JACS, 116, 12212.
polyoxotungstate
►
82%
I .A. 7. Nucleophilic Addition to Electrophilic Carbon
I.A.7.a. l a . Intermolecular Aldol-Tvpe 1.2-Additions
I.A.7.a.la-l Liotta, D.C. et al., TL, 35, 6029 and 4485; see also:
Ettmayer, P. et al., TL, 35, 3901.
w
X
^
l)NaHMDS
2) RCHO
NBn 2
N Bn 2 Me
-A*55-93%, >95%dr