SYNTHESIS OF HETEROCYCLES
267
IV.G-20 White, J.D. et al., JACS, 116, 1831; Lobo, A.M., Prabhakar, S.
et al., TL, 35, 2043.
Phl(OAc),
MeO
OMe
CF 3 CH 2 OH
N H A c
Ji^ J)
NHAc
MeO
F 3 CH 2 CO' 'OMe 72%
IV.G-21 Love, B.E. and Raje, P.S., JOC, 59, 3219.
1. LDA,-78°
2. :
AJQ
59
-
78%)
C X
3. Br 2 /MeOH (85-98%)
4. NaH/THF (85-99%)
IV.G-22 Kaufman, M.D. and Grieco, P.A., JOC, 59, 7197; Waldmann,
H. et al., T, 50, 11865; McNulty, J.and Still, I.W.J., JCS(Pl), 1329.
1. L1CIO4
Et,0
2. CSA
96% Et
IV.G-23 Yang, C-C. et al., CC, 2629.
Pd(OAc) 2
PPh 3 »
R Et 3 N, DMF
100°
N. ^Me
Me 75-88%